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Erythrocytes are high and can generally be divided into two conditions: relative and secondary. Relative increase is usually due to hypovolemia and is common in acute dehydration or burns; Secondary increases are common in chronic hypoxic states, lung diseases, etc.
1. Causes of relative increase in red blood cells.
For some reason, water is lost in the blood, and the blood is concentrated, resulting in a relative increase in red blood cells.
It is generally common in continuous severe vomiting, extensive burns, severe diarrhea, heavy sweating, etc.; It is also seen in chronic adrenal insufficiency, diabetes insipidus, hyperthyroidism, etc.
2. Causes of secondary increase in red blood cells.
The increase in the absolute value of red blood cells in the blood is caused by various reasons, which is mostly related to the lack of oxygen in the body's circulation and tissues. Secondary hyperplasia can be divided into physiological hyperglycosis and pathological hyperplasia.
1) Physiological increase: due to insufficient oxygen content in the environment or some special reasons, the body has tissue hypoxia and causes polycythemia. It is more common in fetuses and newborns, and in people who have been exposed to low oxygen levels for a long time, such as in highland areas.
In addition, drinking too little water, sweating too much, and excreting too much water can also lead to high red blood cells.
2) Pathological hypertrophy: generally caused by insufficient ventilation of the lungs, the body is in a state of hypoxia and causes polycythemia. It is commonly found in lung diseases such as bronchiectasis, cor pulmonale, obesity, pulmonary arteriovenous fistula, cyanotic congenital heart disease, abnormal hemoglobinopathy, etc.
In other cases, there is no tissue hypoxia due to increased bone marrow production of red blood cells, but the increase in red blood cells is not necessary and non-compensatory, and can also cause high red blood cells. It is more common in certain tumors or kidney diseases, such as renal embryonic tissue tumors, adrenal adenomas, polycystic kidneys, renal artery stenosis, hemangioblastoma, etc.
Normal range for red blood cells.
Normal range for red blood cells.
1. Male. 3.8 million to 6 million mm; Normal indicators: to the power of 12 per liter.
2. Female. 3.8 million to 5.5 million mm; Normal indicators: to the power of 12 per liter.
Most of the blood is made up of red blood cells, which carry oxygen from the lungs to tissue cells throughout the body and carry carbon dioxide out.
When the number of red blood cells decreases, the ability to transport oxygen decreases, and it becomes hypoxic, resulting in anemia. In severe cases, it can be life-threatening. However, if it is increased too much, the blood will become thicker, it will not flow easily, and the blood vessels will easily become blocked.
Red blood cells are very small, containing 5 million red blood cells in 1 cubic millimeter of blood, and the number of red blood cells in the human body can reach 25 billion.
The number of red blood cells can vary depending on external conditions and age. Plateau dwellers and newborns can reach more than 6 million mm3. People who play sports or exercise regularly also have a higher number of red blood cells.
The hemoglobin content is 12 15g 100 ml for men and 11 13 g 100 ml for women.
Since there are many causes of high red blood cells, it is best to go to the hospital for a check-up and diagnosis.
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Clinical significance. Polycythemia.
1. Suggesting congenital heart disease, cor pulmonale, emphysema, and maladaptive insufficiency in plateau areas;
2. Diarrhea, sweating and prostration and other lesions that cause dehydration and hemoconcentration;
3. Certain malignant tumors, such as cerebellar hemangioma, kidney cancer, hepatocellular carcinoma, androgen-secreting cell tumors, etc.
Decreased red blood cells.
1 Anemia caused by different causes;
2. Relative decrease in red blood cells caused by hemodilution, such as improper infusion, drinking too much hypotonic solution, etc.
Illustrate. This effect should be taken into account when a large amount of fluid is being transfused at the time of the blood test. Normal reference value for hemoglobin (Hb).
1 male: 120 160 g l (12-16 g dl);
2 Females: 110-150 g L (11-15 g DL);
3 Neonates: 170-200 g l (17 20 g dL).
Clinical significance. Similar to red blood cell count, but hemoglobin measurement is more precise. In anaemia, both decline, but not to a very similar extent.
Depending on the degree of hemoglobin reduction, anemia can be classified into four grades:
mild (hemoglobin 120 g l in males and 110 g l in females);
moderate (hemoglobin 90g l);
severe (hemoglobin 60g l);
Very severe (hemoglobin 30g l).
Illustrate. This effect should be taken into account when a large amount of fluid is being transfused at the time of the blood test. Changes in red blood cell morphology.
Normal reference value.
1 Hematocrit: male: 42 --49; Female: 37 --48 ;
2 Mean Diameter of Red Blood Cells (MCD): Soil;
3 Mean erythrocyte volume (mcv): 80 94fl80—94 m to the third power);
4 Mean hemoglobin (MCH): 26—32pg;
5 Mean hemoglobin concentration of red blood cells (MCHC): 310—350g L;
8 Circulating red blood cell volume: body weight;
9 Reticulocyte count: 24--84x
10 to the 9th power l
10,000 — 10,000 mm to the 3rd power).
Clinical significance. Changes in red blood cell morphology are more significant for anemia, various hematologic disorders, and certain serious diseases. Such as megaloblastic anemia, iron deficiency anemia, hereditary spherocytosis, autoimmune hemolytic anemia, abnormal hemoglobinopathy, thalassemia, severe liver disease, diffuse capillary hemolysis (DIC), uremia, cardiogenic hemolytic anemia, etc.
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Normally, the production and destruction of red blood cells are in a dynamic equilibrium, so the quantity and quality of red blood cells in the blood remain relatively stable. Regardless of the cause, the abnormal production and destruction of red blood cells will cause changes in the quantity or quality of red blood cells, which will lead to the occurrence of diseases. Erythrocytosis is seen in:
1) Patients with severe vomiting, diarrhea, extensive burns and advanced gastrointestinal tumors. It is mostly caused by dehydration, blood concentration and a relative increase in the formed components in the blood. (2) Cardiopulmonary diseases:
Congenital heart disease, chronic lung disease and chronic carbon monoxide poisoning. Due to hypoxia, a large number of red blood cells must be used to maintain the oxygen supply. (3) Stem cell diseases:
Polycythemia vera. Erythrocytopenia is seen in: (1) Acute or chronic blood loss.
2) Red blood cells are damaged by physical, chemical, or biological factors. (3) Lack of hematopoietic factors, hematopoietic disorders and hematopoietic tissue damage. (4) Intravascular or extravascular hemolysis of various causes.
Under physiological conditions, about 1 120 red blood cells die every day in the human body, and at the same time, another 1 120 red blood cells are produced, so that the production and death of red blood cells maintain a dynamic balance. This balance can be disrupted for a variety of reasons, resulting in a decrease or increase in the number of red blood cells and hemoglobin.
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Hello! Not much higher. There's no problem with your red blood cells going a little bit above the threshold. Sometimes, during the fasting test, the blood is relatively concentrated, and it may be high. It's not a disease, don't worry, it may return to normal after a few days.
The cause of this condition is first thought to be due to drinking too little water or sweating too much, and the elimination of too much water can lead to temporary hemoconcentration, resulting in a mild increase in red blood cells and hemoglobin. Then there are symptoms such as severe vomiting, diarrhea, hyperthyroidism, diabetic acidosis, and a significant increase in the amount of red blood cells and hemoglobin due to excessive loss of water in the plasma, which leads to hemoconcentration.
In addition, people in highland areas will also have high red blood cells. Wishing you good health!
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The main causes of high red blood cells are as follows:
1. High pathology.
1. Patients with severe vomiting, diarrhea, large-scale burns and advanced gastrointestinal tumors. It is mostly caused by dehydration, blood concentration and a relative increase in the formed components in the blood.
2. Heart and lung diseases: congenital heart disease, chronic lung disease and chronic carbon monoxide poisoning. Due to hypoxia, a large number of red blood cells must be used to maintain the oxygen supply.
3. Stem cell disease: polycyte eucalypticosis.
2. Physiological hypertremor.
Residents living in highland areas tend to have higher red blood cells and hemoglobin than those living in plains. Drinking too little water or sweating too much, and getting rid of too much water can lead to temporary hemoconcentration, resulting in a mild increase in red blood cells and hemoglobin. Neonates are physiologically elevated.
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First, pathological elevation.
1) Severe vomiting, diarrhea, profuse sweating, extensive burns, diabetes insipidus, hyperthyroidism crisis, diabetic acidosis, etc., due to excessive water loss in the plasma, resulting in hemoconcentration, there will be a significant increase in the amount of red blood cells and hemoglobin.
2) Chronic heart disease, cor pulmonale, cyanotic congenital heart disease, etc., due to tissue hypoxia and increased erythropoietin in the blood, the amount of red blood cells and hemoglobin in the blood is compensated.
3) Some tumors, such as kidney cancer, hepatocellular carcinoma, uterine fibroids, ovarian cancer, renal embryonic carcinoma, etc., can also cause an uncompensatory increase in erythropoietin, resulting in the above results.
4) Polycythemia vera is a blood disease of unknown origin with polycythemia. It is advisable to go to the hospital for examination to further confirm the diagnosis.
2. Physiological increases, such as strenuous labor, fear, cold baths, plateau dwellers, etc.
Third, others, due to some reasons, the loss of water in the plasma, hemoconcentration, so that the content of red blood cells and hemoglobin is relatively increased. Such as drinking less water, sweating profusely, etc.
Suggestions: red blood cells are the main parameters slightly higher (other auxiliary parameters of red blood cells), which may be related to hemoconcentration, it is recommended to test a full set of blood rheology and blood lipids, measure blood pressure, and do an electrocardiogram to see. Not much of a problem in terms of the above results.
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