Early symptoms of ankylosing spondylitis and how are they treated?

Ankylosing spondylitis is the same as rheumatoid arthritis, it is a systemic immune disease, in fact, this disease should be good in the early stage, just found ankylosing spondylitis, timely use of internal medicine **, the first class of drugs is immunosuppressants, with immunosuppressants to suppress the abnormal immune response of the whole body, so that the course of the disease does not progress, the course of the disease does not progress Sacroiliac joint does not fuse, the spine does not reach bony fusion can be moved, this disease has no impact on the patient, so it should be early. Non-steroidal anti-inflammatory drugs can be used to subside the inflammation, and then topical ointments, plasters, and in severe cases, a little hormone drugs can be taken to suppress the immune response. There is also a better drug is a biological agent, called tumor necrosis factor receptor antagonist, which is injected subcutaneously, which can neutralize the abnormal inflammatory factors in the body, so that the body's abnormal immune response will no longer occur, so some people say that biological agents are a kind of drug-based surgical scalpel, which can completely treat the disease.

Early** can prevent future spinal rigidity and comorbidities.

Ankylosing cervical sylitis is a systemic disease of unknown cause, mainly chronic inflammation of axial joints, mainly related to the sacroiliac joints, mostly occurring in adolescent males, usually with slow and insidious onset, and low-grade fever, night sweats, and fatigue in the early stage. Symptoms such as anorexia, emaciation, etc. There is currently no specific drug for ankylosing spondylitis, which can be performed**, mainly to relieve symptoms, maintain good posture and slow down the progression of the disease.

In the early stage, it is necessary to focus on patient education, let them strengthen their long-term determination, encourage patients to adhere to medical physical exercises such as intramuscular injection, thoracic and hip joint activities, and appropriately give non-steroidal anti-inflammatory drugs. or disease-modifying antirheumatic drugs**, or biologic agents can be used to control the condition.

In the early stages of ankylosing spondylitis, it can manifest as pain or discomfort in the lower back, sacroiliac region, buttocks, groin, etc., as well as stiffness in the lower back, which is most pronounced in the morning or when sitting up for a long time, and can be relieved by activity.

Nowadays, people's physical fitness is getting worse and worse, but there are also those who have stronger physical fitness, and the two types are simply very different. This era has been divided into two extreme kinds of people, on the one hand, otaku and otaku. On the other hand, it is a person who often goes to the gym to exercise and likes to do sports.

The lifestyles are different, which also leads to differences in their physical fitness. To be sure, the former is definitely more susceptible to disease than the latter, and the former has a stronger inert mentality. This kind of inertia cannot be manifested in the adult world, there are such things in children, and it is also common.

Early symptoms of ankylosing spondylitisEveryone knows that it is easy to hunch over when using a mobile phone, and it can also lead to cervical spondylosis over time. Today, I'm going to talk about ankylosing spondylitis. In fact, patients with ankylosing spondylitis do not have obvious symptoms in the early stage, and adverse reactions do not appear until the later stage.

Therefore, even if you have ankylosing spondylitis, it is difficult to detect. So what are the early symptoms of ankylosing spondylitis? Some people will have mild anemia, which should be a very insignificant symptom, and some people will have low-grade fever, these slight phenomena will generally not be found in time, and the best opportunity will be missed.

Can it be cured? Ankylosing spondylitis is a disease that involves the immune system. It's the same principle as an allergic reaction, attacking the self as if it were not the self.

But the pain can be alleviated by **. The disease can be hereditary, usually painful in the joints. For the current state of medicine, only immunosuppressants** can be used.

** Maintain a good attitude to make the effect better.

Don't panic Even if ankylosing spondylitis can't be cured, the patient should not panic, after all, the pain can be alleviated by **, and if you take care of it, this disease is not very serious. Therefore, patients must keep their mood comfortable when they are in the first place, and a good mood is the most important thing. And actively cooperate** and listen to the advice given by doctors.

In the early stage, you will feel obvious pain in your waist and back, and some people will also have loss of appetite and weight loss, if it is self-healing, there is no way to do it, so it must be completely cured by medication or surgery.

The early symptoms are very painful and the spine is difficult to stand upright and the degree of curvature is severe. It is very difficult to cure.

It's a little painful, a little stiff, and it's inconvenient to move, but drinking some medicine will have a relieving effect. No, you can't.

The early symptoms are spinal pain, unbalanced walking, and coughing can also be painful, which is a clinical symptom of waking up early, and it is generally difficult to heal and requires long-term **.

925% of patients with ankylosing spondylitis have conjunctivitis, iritis, ocular pigmentitis, or uveitis, which is occasionally complicated by spontaneous anterior chamber hemorrhage. Iritis is easy to **, the longer the disease, the higher the incidence, but it has nothing to do with the severity of spondylitis, it is common in people with peripheral joint disease, and a few can precede spondylitis. Eye disorders are often self-limited, sometimes requiring corticophyllin**, and some can cause glaucoma or blindness if not appropriate**.

10. Ankylosing spondylitis The lesions of the nervous system are mostly due to spinal rigidity and severe osteoporosis, even if the slight trauma is easy to incur spinal fracture and cervical dislocation and spinal cord compression, resulting in different degrees of paraplegia, radicular pain or loss of consciousness, and movement disorders, especially cervical spine fracture, which is the complication with the highest mortality; Occurs in the lumbar spine, it can compress the cauda equina nerve, can become chronic progressive cauda equina syndrome, due to the ossification of the spinal intervertebral disc fibrous annulus, ligamentum flavum, and posterior longitudinal ligament ossification can cause spinal stenosis, but some literature records that myelography does not see spinal stenosis or compressive operation, but can see lumbosacral arachnoid diverticulum, the cause is unclear, may be caused by chronic arachnoiditis, and the initial symptoms of some patients are manifested as lower limb pain and misdiagnosed as sciatica and intervertebral disc herniation.

11 The main manifestations are renal amyloidosis and LGA nephropathy, the incidence of which is similar to that of rheumatoid arthritis, proteinuria can occur, a small number of patients can die due to uremia, and the incidence of prostatitis is higher than that of the general population.

12. The systemic symptoms are generally mild, a small number of people have low-grade fever, fatigue and weight loss, individual patients can have anemia, a small number of acute patients can also have high fever, and those with severe involvement of the joints of the limbs can soon be bedridden, at this time ESR and C-reactive protein can be elevated.

The symptoms of early ankylosing spondylitis are mostly low back pain, which is often simply thought to be lumbar muscle strain, lumbar disc herniation, rheumatoid arthritis and other diseases. Because the symptoms of ankylosing spondylitis are similar to those of other common diseases, the current misdiagnosis rate can reach 80%.

At the beginning of the disease, there are many general weakness, low-grade fever, loss of appetite, anemia, sweating, palpitations, etc. Lesions often initially involve the sacroiliac joints, and patients have low back pain, stiffness in the lower back in the morning, and limited bending. With the development of the disease, the pain gradually intensifies, and the lesion gradually develops from the lumbosacral region upwards to the thoracic and cervical spine, and the spine movement becomes more and more difficult, and finally develops into hunchback deformity, accompanied by scoliosis, and in severe cases, the neck also presents flexion rigidity, the patient can not look up and look forward, cannot walk on the ground, and even daily life such as sitting up, lying down, wearing shoes and socks is also very difficult.

The diagnosis of the disease generally includes laboratory tests, clinical physical examination and imaging tests. Based on the patient's history, combined with clinical symptoms (pain and limited joint motion, rigidity), erythrocyte sedimentation rate, negative rheumatoid factor, and positive HLA-B27.

Symptoms of ankylosing spondylitisObligatory spondylitis is a disease in which inflammation of the sacroiliac joints and spinal entheses is the main symptom. Ankylosing spondylitis is a chronic disease that focuses on the spine. The manifestations of ankylosing spondylitis are generally the initial symptoms, the manifestations of joint lesions, and the extra-articular manifestations.

Symptoms of ankylosing spondylitis1.If the patient has ankylosing spondylitis, young men between the ages of 16 and 25. The performance is more insidious.

In the early stages of long-term spondylitis, almost nothing is detected. Some will show mild legal sales and long-term low-grade fever, anorexia, anemia and other conditions. Because the early stage of ankylosing spondylitis is relatively mild, many patients cannot be detected in time, which will aggravate the condition and lose the best time.

2.Most patients with obligatory spondylitis will develop joint lesions. It may even spread to the cervical spine and spread to other joints.

As the condition of ankylosing spondylitis becomes more and more severe, there will be a certain deformity of the vertebral segments and joints, which occurs in the late stage, remembering that the lower limbs may become arched and flexed forward. As the condition of ankylosing premature nuclear inflammation is further aggravated, the lumbar spine, thoracic spine, cervical spine, and surrounding joints will continue to develop lesions. In addition, other conditions such as pelvis, ischia, femur, etc., can cause osteitis.