What is anti mutant citrulline vimentin antibody

Anti-mutant citrulline.

Vimentin antibody is a biochemical agent for the diagnosis of rheumatoid.

Anti-mutant citrulline vimentin antibody in rheumatoid arthritis.

Significance in diagnosis:

To understand the significance of anti-mutant citrulline vimentin (MCV) antibodies in the diagnosis of rheumatoid arthritis (RA) and to compare anti-MCV antibodies to rheumatoid factor.

RF), anti-nuclear perikine (APF), anti-keratin antibody (AKA), anti-cyclic citrullinated polypeptide (CCP) antibody, and correlations with certain clinical indicators.

Methods ELISA was applied to 166 subjects, including 74 RA patients (including 18 in the early stage and 56 in the middle and late stages), 50 patients with non-RA rheumatic diseases, and 42 healthy controls.

ELISA) was used to detect anti-MCV antibodies in serum, and other relevant autoantibodies were detected at the same time, and analyzed in combination with clinical data. Results Among the 74 cases of RA, 58 were positive for anti-MCV antibody, and the sensitivity and specificity for the diagnosis of RA were 78.

is 95, and the positive and negative values are 97 and 71, respectively. The mean antibody concentrations of anti-MCV antibody positive were (552 380) U ml (Ra group), (162 63) U ml (non-RA group), and (63 46) U ml (healthy control group). The average antibody level was higher in the RA group.

Anti-MCV antibody and anti-CCP antibody were the most correlated (R=-0 502 P=0 000), followed by APF and AKA (R=O 408, P 0 01). There was no significant difference between anti-MCV antibody and various clinical and laboratory indexes (P 0 05). Conclusion Anti-MCV antibody has high sensitivity and specificity in RA, and has a strong correlation with anti-CCP antibody compared with APE and AKA, which can be used as an auxiliary index for the diagnosis of RA.

Anti-MCV antibodies may be independent of disease activity and functional status.

How to understand it out of context.

This indicator is a specific antibody to diagnose rheumatoid, if it is positive, consider early rheumatism, whether other tests are positive or not, it is recommended that you get up early in the morning.

It should be rheumatoid arthritis. Going to the rheumatology and immunology department of a major hospital can control the progression of the disease.

Hello! This is an antibody to cytomegalovirus, which is generally divided into IgG and IgM, and if the former is the former, it means that it has been infected. If the latter is the case, it means a recent infection.

It is recommended to check your test report in detail, whether the antibody is IgG or IgM, and you can judge whether you need to take another one**. You can also upload your inspection report to help you make a comprehensive analysis.

Anti-mutant citrullinated vimentin (anti-MCV) is a surveillance indicator for rheumatic diseases discovered this year.