Is Ebola an RNA virus?

Ebola virus (EBV) belongs to the Filoviridae family and is a long, negative-stranded RNA virus with 18,959 bases and a molecular weight. There is an envelope on the outside, the diameter of the virus particles is about 80 nm, the size is 100 nm (300 1500) nm, and the virus with strong infection ability is generally about (665 805) nm long, with branched, U-shaped, 6-shaped or ring-shaped, and branched shape is more common. There is a capsule with (8 10) nm long fibrils on the surface.

Pure virions consist of a helical ribonucleucleucleoshell complex containing negative-strand linear RNA molecules and four viroid structural proteins.

Ebola virus is an RNA virus. Ebola virus belongs to the Filoviridae family, which is a long filamentous body with a length of 970 nanometers and a diameter of about 80 nanometers, and is a single-stranded negative-stranded RNA virus with 18,959 bases. There is a protein envelope on the outside of the RNA strand.

RNA viruses are first of all prokaryotes, there is no nucleus bounded by the nuclear membrane, and it is easy to mutate due to external influences, and RNA is a single-stranded structure compared with DNA (DNA is a bimolecular helix structure, relatively stable, and it is not easy to mutate genes during transcription and translation) It is easier to have gene mutations during transcription and translation, so RNA viruses are more deadly, and SARS, rabies, Black Death, and AIDS are all caused by RNA viruses.

Learn about Ebola in a minute.

The Ebola virus originated in 1976 in the Bahra Ebola region of southern Sudan and Zaire, now the Democratic Republic of the Congo. The origin of the virus is unknown. The virus is transmitted from wild animals to humans and spreads among people through human-to-human transmission.

However, based on the available evidence, it is thought that fruit bats (Flying Foxes) may be the host of the Ebola virus.

"Ebola" is the name of a river in northern Zaire, the Democratic Republic of the Congo. In 1976, an unknown virus came to the area, killing people in 55 villages along the Ebola River, causing hundreds of lives, some families to be spared, hence the name "Ebola virus".

Three years later (1979), the "Ebola" virus ravaged Sudan again, and corpses were everywhere for a while. After two "atrocities", the "Ebola" virus mysteriously disappeared for 15 years and disappeared without a trace.

Outbreaks in Zaire since January 1995 and Gabon since February 1996: 316 cases and 245 deaths in Kikwit, Zaire, with a case fatality rate of 78%; In Ogooue Ivindo, Gabon, there were 46 cases and 31 deaths, with a case fatality rate.

Scientists have done a lot of research on the Ebola virus, but they have not been able to find the source of the virus. The first outbreak of Marburg virus occurred in 1967 when the patient was exposed to a herd of African green monkeys transported from Uganda. Therefore, it is believed that the Ebola virus is likely to be found in animals in nature.

In October 1989, the Primate Quarantine Center in Leston, USA, received a batch of monkeys from the Philippines. During the quarantine process, the monkeys fell ill and died one by one. When the monkeys' blood was examined, it was found that the monkeys were infected with the Ebola virus.

Fortunately, the Reston Ebola virus is not pathogenic to humans and does not cause illness in humans. But this finding reminds us that the Ebola virus is likely to be like the Marburg virus in monkeys, orangutans and other non-human primates. But it was later discovered that non-human primates were also victims of the Ebola virus.

During the 2001-2003 Ebola haemorrhagic fever outbreak in Gabon and Congo, French scientists captured thousands of different animals, including bats, birds, squirrels, etc., in endemic areas and tested them for Ebola virus. As a result, evidence of the existence of the Ebola virus was detected in the bodies of 29 bats, and it is suspected that bats could be the culprit in the transmission of the Ebola virus. The study also found that some of the characteristics of the Ebola virus are similar to those of a variety of retroviruses that can infect birds, and it is speculated that the Ebola virus and the retroviruses circulating in birds may be the same ancestor.

In 2008, the United States was assisting the Philippines in quarantining some sick pigs and found that pigs could be infected with the Ebola virus.

This is despite growing evidence that the Ebola virus is transmitted from animals to humans. But so far, the exact ** of the Ebola virus remains unclear.

It is the polluted environment of Africa. The place is unhygienic, and all kinds of garbage are piled together, resulting in the production of a mutated bacterium, which is called a virus because it cannot be killed and can be infected. Many animal areas in Africa are very different kinds of garbage heaps, which are very unsanitary and dirty.

The virus happens to be exposed to animals and then infected when people go to catch them. Then when I returned to the village, I spread it to everyone. Think about why there are no outbreaks of this deadly virus in so many countries around the world, but there are always outbreaks of various viruses in Africa.

The Ebola virus spreads so quickly that blood, saliva, urine and other body fluids are the source of infection, and without any precautions, a large number of infected people will appear immediately.

Because the lethality rate of this virus is very high, people often die before they can wait for medicine, and there is no very good specific medicine.

Because the medical conditions in Africa are relatively poor, there are many local people, and there is a lack of scientific medical awareness.

China is talking: Professor Chen Wei talks about the origin of the Ebola virus.

Formation of the Ebola virus:

Ebola is the name of a river in the northern part of the Democratic Republic of the Congo (formerly known as Zaire). In 1976, an unknown virus came to the area, killing people in 55 villages along the Ebola River, causing hundreds of lives, some families to be spared, hence the name "Ebola virus".

Ebola is a zoonotic virus, and despite painstaking research by the World Health Organization, no animal reservoir capable of surviving an outbreak has been identified, and fruit bats are considered to be the possible original reservoir of the virus.

Ebola virus is also known as Ebola virus. It is a very rare virus, which attracted wide attention and attention from the medical community after its existence was discovered in 1976 in the Ebola River region of southern Sudan and the Democratic Republic of the Congo (formerly known as Zaire).

Hence the name "Ebola". is a general term used to refer to a group of viruses belonging to the genus Ebola in the family Fibriviridae.

Ebola virus is a virulent infectious virus that can cause Ebola hemorrhagic fever in humans and other primates, and the Ebola hemorrhagic fever (EBHF) caused by it is the deadliest viral hemorrhagic fever in the world today, and the symptoms of infected people are very similar to Marburg virus, which is also in the fibroviridae family, including nausea, vomiting, diarrhea, skin color changes, body aches, internal bleeding, external bleeding, fever, etc.

Mortality rates range from 50% to 90%, and the main causes of death are stroke, myocardial infarction, hypovolemic shock, or multiple organ failure.

Ebola virus, biosafety level 4 (AIDS level 3, SARS level 3, the higher the level, the stricter the protection). The incubation period of the virus can range from 2 to 21 days, but it is usually only 5 to 10 days.

The Ebola virus was not first discovered in humans, but in animals. Similar to the spread of the Ebola virus, many deadly viruses in human history have come from animals. Human infection is also inseparable from social development and living conditions.

"Ebola" is the name of a river in central Africa.

In 1976, an unknown virus visited the area, killing hundreds of people in 55 villages along the coast. Two months later, the virus ravaged Sudan. Over the next nearly 40 years, Ebola showed its sharp teeth several times.

In 1979, the Ebola virus ravaged Sudan. After nearly 15 years of obscurity, it has swept the Congo and Gabon again.

According to current research, fruit bats in the wild are likely to be one of the animal reservoirs for the Ebola virus. As for why humans are infected with the Ebola virus, we must find out the reason from our own living habits.

According to Zhang Xue, a medical scientist from the popular science ** "Guohu.com", told the Beijing News reporter that the Ebola virus was not first found in the human body, but in the animal body. The reason why Africans are infected with Ebola virus is related to two habits: one is that they have the habit of eating raw animals, such as monkeys or fruit bats containing Ebola virus, and the other is funeral customs - after death, the body of a person will be disemboweled, the intestines are cleaned, and the food residue is washed out, in the process, people are easily infected with the Ebola virus.

Similar to the spread of the Ebola virus, many deadly viruses in human history have come from animals. Human infection is also inseparable from social development and living conditions.

Historically, after Columbus discovered the New World, the colds and smallpox brought by Westerners killed a large number of Indians. And the disease that the aborigines transmitted to the European colonizers was only syphilis, which was not fatal.

In fact, almost all the famous large-scale and deadly infectious diseases in human history, including smallpox, influenza, malaria, plague, measles, cholera, and in recent years, AIDS, avian influenza, foot-and-mouth disease, etc., have been inherited from animals by humans.

Diamond, a physiologist at the University of California, Los Angeles, pointed out in his book "Guns, Bacteria, Steel: The Destinies of Human Society" that the viruses and germs of human infectious diseases are the products of livestock and poultry breeding in agrarian societies. The agrarian societies of the Old World were thrived by animal husbandry and dense populations, which were hotbeds of infectious diseases.

Learn about Ebola in a minute.

Ebola virus disease is an acute hemorrhagic infectious disease caused by the Ebola virus in the family Filoviridae. It is mainly transmitted through the patient's blood and excreta

The main clinical manifestations are acute onset, fever, myalgia, hemorrhage, rash and liver and kidney damage. Ebola hemorrhagic fever caused by the Ebola virus is mainly endemic in central Africa and other places, and is extremely rare in Asia, so it should not be, if you are unsure, it is recommended to see a doctor.

Introduction to the virus.

Ticks are not only found in Japan, but also in Japan, and most people know how terrible ticks are. After being bitten by a tick, the tick will pass the virus through the body's bloodstream, and eventually the patient will develop a high fever and be aware of the loss of appetite. After the examination, the number of platelets and white blood cells in the patient's body decreases.

After investigation, it was indeed found that the virus was transmitted by ticks. In addition, Japanese scientists have also proved through research that the virus exists in ticks, and the virus is also transmitted to the human body through tick bites.

The African Ebola virus is a filovirus, it is a negative-strand RNA virus, it can cause Ebola hemorrhagic fever, it has a lot of different symptoms, it has a fatality rate of 50 to 10 percent, it is a zoonotic virus. There are five different species of the Ebola virus.