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Brain atrophy refers to the phenomenon of atrophy caused by organic lesions in the brain tissue itself due to various reasons. Physiologically, the volume of brain tissue is reduced, the number of cells is reduced, and the ventricles and subarachnoid space are enlarged. The disease mostly occurs in people over 50 years old, the course of the disease can reach several years to decades, more men than women, can be divided into diffuse brain atrophy (including cortical atrophy, cerebellar atrophy and cortex, cerebellum, brainstem atrophy) and localized brain atrophy (more common after localized brain organic lesions such as trauma, vascular disease, intracranial localized ** infection, etc.).
Brain atrophy is a neuroimaging manifestation of many diseases, as it was originally named after the reduction in the size of brain tissue and the enlargement of the ventricles during CT or MRI examinations.
The clinical manifestations of cerebral atrophy can be divided into two categories: cerebral function decline and cognitive decline, which are mainly related to the location and degree of cerebral atrophy. Diffuse cerebral cortex atrophy is mainly characterized by dementia, mental retardation, memory impairment, personality changes, and behavioral disorders. Some are accompanied by hemiplegia and seizures.
Focal brain atrophy is dominated by personality and behavioral changes; Cerebellar atrophy is dominated by speech impairment, limb ataxia, and intention tremor.
1.Systemic symptoms.
In the early stage of the lesion, patients often have dizziness and headache, insomnia and dreams, soreness in the waist and knees, numbness in the hands and feet, tinnitus and deafness, and gradually become unresponsive, slow in movement, muttering, and answering questions that are not answered. In the physical aspect, it is often manifested as senile state of dragon clock, white tooth loss, dryness, pigmentation, or hemiplegia, epilepsy, ataxia, tremor, etc., and neurological symptoms may or may not be present.
2.Memory impairment.
Memory loss of recent events occurs earlier, such as frequent loss of objects and forgetting promised things. As the disease progresses, it gradually leads to complete loss of memory.
3.Changes in personality behavior.
Personality changes are often an early symptom of the disease, with people becoming depressed and disliking people; or manifested as a lack of ideals, desires, and feelings for their children and relatives; or have rigid and bizarre living habits, impatient personality, increased speech or verbosity, suspicious and selfish; or have a special concern for their own health and safety, and are often entangled by some minor discomforts; or manifested by amnesia or mania, with delusions, visual hallucinations, auditory hallucinations, aphasia, and agnosia. All high-level emotional activities, shame, responsibility, honor and morality are reduced to varying degrees, and sleep rhythm changes can also occur.
4.Mental retardation, dementia.
It is manifested as an overall decline in intellectual activities such as comprehension, judgment, and calculation ability, unable to adapt to social life, and difficult to be competent for work and household chores; Gradually, they can't correct their names, ages, eat, don't know how to eat, don't know how to go home, and collect waste paper and sundries as treasures. In the later stage of the disease, he was bedridden all day long, unable to take care of himself, did not care for himself, was incontinent, slurred speech, slurred speech, and finally became completely demented.
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The earliest manifestations of brain atrophy are mainly mild cognitive impairment: forgetfulness. The response to accidents is not as sensitive as before.
Go to the hospital for a check-up. No disease has been identified that explains the cause of these changes. If early symptoms go unnoticed.
When mild to moderate brain atrophy develops. Symptoms will gradually worsen. Such as doing things in a disgraceful way; Forget when you're done; Getting dressed is slower than before; I can't remember all the steps of cooking; When talking to people, I often can't remember some simple words.
Or replace it with words that are not commonly used. making it difficult to understand what is said and what is written; I can't remember where my home is when I go out. how to return; It turns out that diligent people slowly get tired of housework and social activities; Sometimes emotions fluctuate for no apparent reason.
Extremely unstable. They may even become suspicious, depressed, apathetic, anxious, or rude.
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What are the symptoms of brain atrophy
Cerebral atrophy refers to the atrophy of vocal organic lesions of brain tissue due to various reasons. It is mainly the elderly and those with arteriosclerosis who have a higher incidence rate. Brain atrophy not only affects intellectual development, but is also likely to cause patients to lose their autonomous instinct to live, affect their quality of life, and even endanger their lives.
What are the symptoms of brain atrophy
First, systemic symptoms. Patients with pre-lesions often present with a wide variety of symptoms throughout the body. For example, dizziness and headache, insomnia, dreaminess, numbness in the hands and feet, tinnitus, deafness, unresponsiveness, answering questions and so on. There may be some loss of function in both the body and the nervous system.
Second, memory impairment. At the beginning of the illness, it may just be that you often lose your belongings and forget about recent events. As the disease gets worse and worse, the memory will also be completely lost.
3. Change personality and behavior. The early symptom of cerebral atrophy is that the patient begins to be depressed and reluctant to socialize with others. It may also show indifference to children and loved ones, lack of affection, and lack of desire.
Or the habits of life have become rigid, the nuclear is weird, the personality is becoming more and more impatient, the words increase or the brother's deeds repeat a sentence, selfishness and suspicion, etc. Many. Higher emotional activities such as shame, responsibility, honor, and morality will diminish somewhat.
Fourth, intelligence declines. That is, Lao Wei said, patients may have an overall decline in intellectual activities such as comprehension, judgment and calculation skills. They may gradually find it difficult to socialize and work.
In the later stages, the patient may not even be able to correct his name, age, be bedridden all day long, and finally become completely demented.
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Cerebral atrophy has a slow onset and progressively worsens, and the date of onset is difficult to determine in most patients. The clinical manifestations are related to the location and degree of cerebral atrophy. Among them, diffuse cerebral cortex atrophy is mainly dementia, mental retardation, memory impairment, personality changes, and behavioral disorders.
Some are accompanied by hemiplegia and seizures. Focal cerebral atrophy is dominated by personality changes; Cerebellar atrophy is characterized by speech impairment and astaxia and tremor of the body. From the analysis of the clinical manifestations of cerebral atrophy, it can be roughly divided into two categories, one is the decline of brain function, and the other is the decline of intelligence such as dementia.
The decline of brain function is manifested as dizziness, headache, insomnia, poor memory, numbness in the hands and feet, depression, etc.; Mental retardation manifests as impairment of cognitive and social adaptability, such as memory, comprehension, judgment, numeracy, and even dementia.
1) Changes in personality and behavior Personality changes are often an early symptom of the disease, patients become withdrawn, do not like to interact with others, or show no ideals, desires, and lack of affection for their children and relatives; Rigid and bizarre habits, impatient personality, increased speech, or verbosity; Or suspicious and selfish, with a special concern for their own health and safety, often entangled by some minor discomfort. All patients had varying degrees of decline in higher emotional activity--- shame, responsibility, honor, and morality, and may also have changes in sleep rhythms.
2) Memory impairment Memory impairment occurs earlier, such as frequent loss of objects, forgetting promised things, etc. As the disease progresses, it gradually leads to complete loss of memory.
3) Mental retardation and dementia are manifested as a general decline in intellectual activities such as comprehension, judgment, and calculation ability, unable to adapt to social life, and difficult to be competent for work and housework; Gradually, I can't answer my name correctly, my age, I don't know how to eat and I don't know how to get home, and I don't know how to return after going out, and I collect waste paper and miscellaneous items as treasures. In the later stage of the disease, he was bedridden all day long, unable to take care of himself, incontinent, incontinent, slurred, slurred, and disorganized, and finally completely demented.
4) Systemic symptoms In the early stage of the lesion, patients often have dizziness and headache, insomnia and dreams, soreness in the waist and knees, numbness in the hands and feet, tinnitus and deafness; Gradually, he became unresponsive, slow-moving, muttering, and answering questions that were not answered. In the physical aspect, it is often manifested as senile state of the dragon clock, whitish teeth, dryness, hyperpigmentation, or even hemiplegia, epilepsy, or ataxia, tremor, etc., and neurological symptoms may or may not be present.
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The early manifestations of cerebral atrophy are:
Dizziness, headache, memory loss, gradual loss of time, place, and orientation (e.g., unable to find a home when you leave the house), fragmented thinking, neglect of major events, entanglement of trivial matters, frequent occurrence of various meaningless repetitive activities, decreased intelligence, and slow response;
Personality and personality changes are often manifested as: selfishness, strong subjectivity, impatience and irritability, anxiety, irrationality, suspiciousness, incoherent speech, indifference to others, etc., and finally the patient gradually appears emaciation, unsteady gait, slow movements, and even hemiplegia, total paralysis and bedridden, incontinence, bedsores, fantasies, hallucinations, aphasia, agnosia, etc.
The above symptoms are not very obvious in some patients, and they are often thought to be common phenomena in the elderly, and they are often easy to be ignored, so those who have the above phenomena should pay attention to and check in time to diagnose ** to avoid getting worse.
Brain diseases such as cerebral atrophy, dementia, and sequelae of stroke, in the final analysis, all coexist in the following ways: 1physiological factors; 2.psychological factors; 3.pathological factors; 4.Congenital factors.
Cerebral atrophy and stroke are serious diseases that damage the health of middle-aged and elderly people, so that patients lose their independent instinct in life and work, develop to the ability to live, and the body's ability to control is completely reduced, until they are bedridden.
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Brain atrophy is a chronic mental degenerative disease. Clinically, memory impairment, affective disorders, changes in personality and behavior, and mental retardation are the main characteristics. The disease mostly occurs in patients over 50 years old, and the course of the disease can last for several years or even more than 10 years, and women are more likely than men.
It can be divided into cerebral arteriosclerotic cerebral atrophy, senile dementia cerebral atrophy, cerebral atrophy after stroke, cerebral cerebral atrophy caused by cerebral arterial insufficiency after cervical spondylosis and traumatic brain injury, and hypoxic cerebral atrophy after asphyxia in children. So; If you are a young person; If there is no special illness; It doesn't have to be that there is really brain atrophy. Instead, it is advisable to look for cervical spine or other non-cerebral organic lesions.
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Near memory loss and long-term memory are not impaired.
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The main symptoms of brain atrophy are as follows:
1. Memory loss or even gradual loss. It is manifested in the fact that I often forget what I have done before, I can't find the items I have put away, I can't remember the things that I have planned without being reminded by others, and in serious cases, I can't remember that I have made a plan even if I am reminded by others.
2. Mental retardation. It is manifested as an overall decline in intellectual abilities such as comprehension, judgment, and calculation ability, and then symptoms such as getting lost when going out, wrong mouth, slurred speech, and slurred speech.
3. Changes in personality and behavior. It is manifested as depression, often sitting, not talking, and even dull eyes.
4. Accompanied by other diseases, such as hypertension, coronary heart disease, stroke hemiplegia, epilepsy and diabetes, ataxia tremor paralysis, etc.
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The main manifestations of the patient are restlessness, depression and paranoia, and there will be headache, dizziness, insomnia or drowsiness, obvious forgetfulness, insufficient blood supply to the cerebral arteries, memory loss and other signs. However, at this stage, the patient has not yet developed cognitive dysfunction, and CT and MRI cannot detect brain atrophy, so it belongs to the early stage of the lesion and is the best prevention period. Patients may experience long-term headache, dizziness, forgetfulness (such as forgetting what to eat just after eating), insomnia, waist and knee soreness, numbness of hands and feet, frequent urination, and urgency.
Obvious abnormalities in emotional behavior, suspicious, selfish, unresponsive, slow in action, etc.
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The main causes are memory loss (often unable to find their own home**), decreased intelligence, unresponsiveness, apathy, emotional instability, and changes in temperament. It is more common in older people. Generally, senile dementia has a certain amount of brain atrophy and demyelination of the white matter of the brain.
Of course, brain atrophy can also be seen in traumatic brain injury.
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1. Loss of autonomy:
Sometimes people get bored with housework, work, or social interactions, but people with Alzheimer's become very passive about everything. You need the prompting and promotion of others to participate in normal social activities.
2. The ability to think and induct is extremely reduced
People who can deal with digital problems normally sometimes have a clue because things are more complicated, but they will always find a solution that works. People with Alzheimer's disease not only forget numbers, but also how they are used.
3. Significant impairment of judgment:
When people are so engrossed in an activity that they may forget about other things for a while, such as taking care of their children in a timely manner, but remember it later. However, people with Alzheimer's disease will completely forget the child they are caring for and go out alone for a long time, unable to remember that the child needs to be cared for.
4. Language barrier:
Everyone may have a time when they can't find the right words. But it is often replaced by other appropriate words. People with Alzheimer's often forget words or combine incoherent words in an incomprehensible way.
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