Ankylosing spondylitis, is it genetic? How is hereditary ankylosing spondylitis cured? What do you k

Ankylosing spondylitis is hereditary, and if someone in an immediate family member, such as a parent, grandparents, or sibling, is diagnosed with ankylosing spondylitis, it can be passed on to a child.

This inheritance is probable, not absolute. It is thought that ankylosing spondylitis is more easily passed on to boys and less often to girls.

And even if it is passed on to girls, ankylosing spondylitis in girls generally does not receive special attention because the onset is slow and the progression is not rapid. And if it is inherited to boys, many of them start to develop the disease when they are teenagers or even young adults, and the disease progresses rapidly, if it is not properly treated, sacroiliitis will soon appear, and it will accumulate upwards of the spine, resulting in stiffness of the spine and even fusion.

Therefore, ankylosing spondylitis should be prevented and standardized.

There are several factors that cause ankylosing spondylitis:

1) Genetic factors: The onset of this disease is closely related to genetic factors, such as HLA B27 for ankylosing spondylitis

The positivity rate is as high as 90% to 96%, and the familial genetic positivity rate is as high. The incidence of rheumatoid disease in its family is 2 1 in normal people

0 times, while the incidence of ankylosing spondylitis in families is 30 times higher than normal.

2) Infectious factors: Genitourinary infection is one of the important factors causing this disease, pelvic infection spreads to the sacroiliac joint and then to the spine through the lymphatic route, and can also spread to the general circulation and produce systemic symptoms and lesions of the surrounding joints, tendons and ocular pigment membranes.

3) Endocrine disorders or metabolic disorders: Since rheumatoid is more common in women, and ankylosing spondylitis is more common in men, it is believed that endocrine disorders are related to this disease. However, the use of hormones ** rheumatoid has not achieved significant results, and the relationship between hormone imbalance and this disease has not been confirmed.

There is no significant increase or decrease in the incidence of rheumatoid or ankylosing spondylitis in patients with hyperadrenal cortex.

4) Other factors: age, physical fitness, malnutrition, climate, soil and water, humidity and cold. Others, including trauma, parathyroid disease, upper respiratory tract infection, and local purulent infection, may be related to this disease, but the evidence is insufficient.

Ankylosing spondylitis is a chronic inflammatory disease that mainly affects the axial bones, the hallmark of this disease is sacroiliitis, it's **: the first is genetic factors, genetic factors play an important role in the onset of ankylosing spondylitis, the positive rate of HLA-B27 in ankylosing spondylitis is as high as 96%, and the positive rate of its immediate relatives is 58%, while the general population is only about 6%. The second is infection, which is often associated with prostatitis, ulcerative colitis, and pelvic infection, which spreads to the sacroiliac joints via the lymphatic route.

Third, autoimmunity, 60% of patients with ankylosing spondylitis have increased complement in the blood, and there are immune complexes in the blood.

In fact, for ankylosing spondylitis, in addition to some drugs and physical **, the most ideal way to assist is to do some correct posture movements. In the use of some pure Chinese medicine patches, such as:

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**The best and most effective way to treat ankylosing spondylitis is to use it.

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When encountering such a situation of love bridge spikes, I think it can be done by shouting in the way of chemotherapy, or it can be done by surgery. Try to choose the way of surgery, the effect is better than the sensitive excitation, and the probability of success is greater.

Taking a comprehensive approach**, the doctor will give a conservative plan, first to control the condition with medication, then to correct the spine column through surgery, then to eliminate the inflammation of the cleft, and then to restore the wax through physiotherapy.

It is necessary to find a professional doctor to carry out**, and it should also be carried out with relevant drugs**. It is necessary to be blind and reasonable with your own diet, and you should pay attention to rest and accept it when you are usually empty, and you should be conservative**.

At present, there is no complete way to ankylosing spondylitis, it is a self-immune disease, but early detection as soon as possible can effectively control the condition and will not affect normal life. In severe cases, it may cause deformity of the spine, resulting in paralysis. If it has been diagnosed, it needs to be timely**, in addition to drugs**, you can also relieve the condition through physical therapy, such as acupuncture, massage, massage, infrared irradiation, intermediate frequency pulses, etc.

Patients also need to exercise regularly to ensure the proper functioning of the limb.

Heredity is only a concurrent cause of ankylosing spondylitis, there are many reasons for the onset of ankylosing spondylitis, and it is best to be timely for such a disease.

Prevention of infection: avoidance of infectious diseases, epidemic invasion, prevention of colds and diarrhoea and reproductive hygiene. Pay attention to your diet.

Tobacco and alcohol should be self-controlled, and should be avoided as much as possible. Pay attention to keeping warm: pay special attention to the warmth of the lower back, choose a sunny house to live in winter, and avoid being in the wind when sweating, because the pores are open when sweating and the wind is easy to invade.

The special sticker of Zhongsheng ankylosis o has a good effect.

There is a possibility of heredity, but it does not mean that everyone will get sick! The following is the specific information on the genetic possibility of ankylosing spondylitis, I hope it can help you! The jury is still out on whether ankylosing spondylitis is genetic, but 90% of people with ankylosing spondylitis have a genetic component.

So ankylosing spondylitis is a disease that is closely related to genetics. Studies have shown that ankylosing spondylitis is closely related to HLA-B27, and the onset of ankylosing spondylitis is directly related to HLA-B27, that is, ankylosing spondylitis is strongly associated with human leukocyte antigens, 80 of HLA-B27 positive patients do not develop ankylosing spondylitis, and 10 of patients with ankylosing spondylitis are HLA-B27 negative. Therefore, HLA-B27 positive does not necessarily cause ankylosing spondylitis, HLA-B27 negative does not necessarily do not cause ankylosing spondylitis, and HLA-B27 positive cannot be considered ankylosing spondylitis.

It is safe to say that only a few people in the family of ankylosing spondylitis will become ankylosing spondylitis, and most people will never develop the disease. In 1964, Kell-Gren found that the average prevalence of the disease in the family of patients was 4, while the average prevalence of the national population was only, and the incidence difference between the two was 40 times, indicating that the familial hereditary nature is indeed related to the onset of ankylosing spondylitis. Brewerton et al. (1973) obtained evidence of obvious genetic factors in the tissue classification of patients with ankylosing spondylitis, and they found that 72 cases of HLA-B27 were positive in 75 typical patients, accounting for 96 cases, and in 31 of their 60 first-degree relatives (51 percent), HLA-B27 was positive in 3 cases, accounting for 4 cases, and in 75 control groups, only 3 cases of HLA-B27 were positive, accounting for 4, indicating that HLA-B27 positive patients were closely related to the onset of ankylosing spondylitis.

Because the HLA system, like blood group antigens, is genetically determined, heredity is one of the important causes of ankylosing spondylitis. In the HLA-B27-positive population, the incidence of the disease accounts for about 20, and the remaining 80 do not suffer from the disease, indicating that there are other pathogens in addition to genetic factors. Clinical studies have found that the onset of ankylosing spondylitis is closely related to the body's own immune disorders, and patients with ankylosing spondylitis have found that immunoglobulin, CF-reactive protein, C, and C have changed to varying degrees in immunological examination, which indicates that ankylosing spondylitis is related to autoimmune function, and ankylosing spondylitis is also related to systemic inflammation, ankylosing spondylitis is closely related to various organs of the body, and ankylosing spondylitis is related to internal medicine.

Ankylosing spondylitis eventually affects the bones and joints of the whole body, and ankylosing spondylitis is related to orthopedics. Therefore, ankylosing spondylitis, a multidisciplinary disease, is a hereditary immune orthopedic disease, in the first place, we should start from autoimmune regulation, combined with anti-inflammatory and pain-relieving, absorb dead bone, early control of the disease, and reduce the disability rate of ankylosing spondylitis.

Hello, the incidence of ankylosing spondylitis in the general population, and in families that are already ill, the prevalence is up to 4, which is 40 times higher than in the general population. This finding shows that ankylosing spondylitis will be inherited, and there is an obvious familial genetic tendency, it is recommended that patients choose a regular professional hospital for diagnosis, and develop a plan suitable for the patient's condition, accept a comprehensive and scientific, and protect the joint spine.