Why is epilepsy inherited from one generation to the next? Is epilepsy inherited from one generation

Epilepsy can be inherited, so primary epilepsy may be inherited from one generation to another, but the chance of inheritance from one generation to another generation will be lower. In general, the chance of developing epilepsy in the third generation may be about 20% higher than that of normal people. However, intergenerational inheritance is recessive and does not necessarily mean absolute inheritance.

Therefore, patients with primary epilepsy should pay close attention to the presence of seizures in their offspring, and should be diagnosed as soon as possible**.

Epilepsy is a common disease, the probability of his inheritance is not very large, the probability of intergenerational inheritance is even smaller, many people are afraid of heredity, dare not marry a patient with epilepsy in the family, in fact, there is no need to worry about this, not close relatives or both are epilepsy is fine.

Epilepsy is not necessarily caused by intergenerational inheritance, there are many types of epilepsy, usually primary epilepsy and secondary epilepsy, most epilepsy is not caused by heredity, it is caused by acquired factors, such as birth trauma, encephalitis, brain trauma, etc., will cause epilepsy, epilepsy symptoms are often atypical, sometimes there are body convulsions, which have a great impact on the body, and anti-epileptic drugs need to be used as soon as possible**. If it is a secondary epilepsy, it is necessary to use a positive ** for the primary disease, and the physical symptoms can disappear after the primary disease is controlled.

Epilepsy can be inherited from one generation to the next. The heredity of epilepsy is mainly related to chromosomes, mainly related to genes. There are still symptoms of epilepsy, primary epilepsy is genetically predisposed, but the probability of intergenerational inheritance is relatively lower than that of the second generation, and the probability of the third generation is about 20% of that of normal people.

The incidence is less than 1% in relatives of secondary patients, and heredity is almost nil. Among the relatives of people with epilepsy, the closer the blood relationship, the greater the chance of inheritance.

Epilepsy does have a hereditary chance, but it's not a given. Epidemiological surveys have confirmed that the familial incidence of primary epilepsy is higher than that of the general population, and that the familial incidence of secondary epilepsy is also higher than that of the general population. The familial incidence of primary epilepsy is higher than that of secondary epilepsy.

Epilepsy can be inherited from one generation to another, but not all epilepsy is inherited from one generation to another, and secondary epilepsy is not inherited.

1 Epilepsy is genetic.

Epilepsy is hereditary silver-carrying hailstone, but not all epilepsy is caused by genetics, epilepsy due to heredity is only one aspect of epilepsy**, in addition, epileptic seizures are also related to birth trauma, brain hypoplasia, poisoning, metabolic diseases, trauma and other factors.

2 The so-called intergenerational inheritance means that the first generation and the third generation have similar symptoms, and the second generation does not have the disease, and for epilepsy, even if the second generation does not have the disease, there may be recessive genes for epilepsy in the body, and if you marry a partner who also has a family history of epilepsy, it is entirely possible to pass it on to the next generation.

3. Monogenic inheritance: the phenomenon caused by a specific gene abnormality or defect on the chromosome, including chromosomal dominant inheritance, autosomal inheritance and X-sex linkage inheritance.

Polygenic inheritance: Polygenic inheritance refers to epilepsy caused by mutations in multiple genes on chromosomes.

41.Prohibition of consanguineous marriage: For people with a family history of epilepsy, even if they do not have epilepsy, they should avoid consanguineous marriage, which can prevent the phenomenon of intergenerational inheritance.

2.For patients with frequent seizures, marriage and childbearing should not be considered, because epilepsy will lead to systemic hypoxia, resulting in fetal hypoxia, affecting the normal development of the fetus. If you take anti-epileptic medications, it can also cause poor fetal growth.

3.For patients with a family history of epilepsy on both partners, consider avoiding marriage even if they are not close relatives.

Hello, there is a genetic factor in epilepsy and it can be passed on from generation to generation, according to research, the number of children of epilepsy patients is about three to four times higher than the normal population, but it is known that the more distant the blood relationship, the less chance of inheritance. In addition, the congenital epilepsy factors caused by heredity must work together with the acquired environmental factors to develop the disease, so to avoid the onset of the offspring of epilepsy patients, it is necessary to actively control the acquired environmental factors and create a healthy and comfortable environment for the offspring of the patients.

Hello. The hereditary nature of epilepsy is not very certain, as the condition and genes of each person with epilepsy will be different. Remind epilepsy patients who want to have children that it is best to have epilepsy after it is well controlled, so that the chance of losing the tradition will be very low.

Epilepsy has a serious impact on the life and work of patients, and many people think that epilepsy patients only have epilepsy if they are genetic, which is only a one-sided understandingEpilepsy is divided into primary and secondary, and the secondary is usually caused by trauma. So don't just take it a one-sided way.

Many times in the outpatient clinic, some patients will ask, will epilepsy be inherited from one generation to the other? In the outpatient clinic, I see many patients whose parents do not have epilepsy, but whose children have epilepsy. Most of the detailed inquiries are about the children's grandfathers, grandmothers, or grandfathers and grandmothers who have different degrees of epilepsy.

So,Epilepsy is inherited from generation to generation.

Specific introduction and manifestations of intergenerational inheritance:

Epilepsy has just mentioned whether it will be inherited, for primary epilepsy, there is still a genetic tendency, but the intergenerational inheritance, relatively speaking, is lower than the second generation, the incidence is lower, but for some patients with primary epilepsy, the probability of the third generation may be about 20% higher than that of normal people, of course, for some secondary patients, epilepsy is generally not inherited, epilepsy in a few cases, there are irregular genetic factors, the impact on most of them is not great.

Then the size of the impact is related to **, among the relatives of the primary patient, the incidence rate of the patient is 3% to 4%, then the secondary, the patient incidence rate is 0 to 1%, indicating that the primary impact is relatively large, but for secondary epilepsy, relatively speaking, the probability of intergenerational inheritance is very small, generally speaking, the third generation of the onset of the disease, the incidence of the third generation of primary epilepsy increases, which is about 20% higher than that of normal people, so although the primary patient can get married.

But try to limit fertility, epilepsy patients in the choice of mate, try not to choose, have suffered from epilepsy, or electroencephalogram, patients with abnormal epileptic waves, blood relations are generally the farther away the better, in addition to the fetus The impact is mainly on the mother, relatively speaking, the heredity of epilepsy, the impact on the father, is affected by the father, relatively small, so generally speaking, the father with epilepsy, generally do not need to be too anxious, because relatively speaking, The chromosomes of the fetus include cellular components, mainly those of the mother.

I believe we all know that epilepsy is a chronic disease of transient brain dysfunction, and epilepsy poses a certain threat to the life and health of patients, and is a very headache disease, and epilepsy is hereditary, so? In response to this problem, let's listen to the analysis of experts.

Epileptic seizure is a clinical phenomenon caused by abnormal and excessive hypersynchronous firing of brain neurons. It is characterized by sudden and transient symptoms that manifest themselves in a variety of ways depending on where the abnormally firing neurons are located in the brain, and can be motor-sensory, psychological, or autonomic with or without changes in the degree of consciousness or alertness.

Epilepsy is a common neurological disorder, with a prevalence of epilepsy according to the World Health Organization. There are a total of 50 million epilepsy patients in the world, and there are about 6 million patients in China, with two peaks, children and the elderly, with an incidence of 35.1 million in China, and about 300,000 new patients every year. So?

2.Cryptogenic epilepsy (undetected by current testing**). 3.

Symptomatic epilepsy, which can detect definite epilepsy.

Experts suggest that people with a family history have a greater chance of developing epilepsy in the next generation than the next generation without a family history, but the chance of epilepsy inheritance is very small, and the chance of intergenerational inheritance is even smaller, so there is no need to worry too much. Don't worry about this problem, if you want to have children after getting married, and your lover has no epilepsy and no family history, the chance of inheritance is very small.

Hello, epilepsy is a suspicious genetic predisposition without other obvious **, often onset at a special age, so if there are epilepsy patients in the family, it is possible to have a genetic risk of intergenerational or intergenerational, but now that medicine is promising, there are already some drugs that can be **.

Epilepsy heredity is mostly related to the patient's epilepsy condition and type, and the genetic probability of congenital epilepsy is higher than that of secondary epilepsy.

Epileptogenic areas of the brain are surgically removed to prevent seizures. However, there are certain risks in surgery**, and it must be decided by experts in combination with the patient's condition, after careful analysis and discussion, and it is recommended not to take surgery if it is not particularly stubborn epilepsy**.

Many scholars at home and abroad have conducted studies from many aspects, such as the prevalence of epilepsy family members with different morbidities, the prevalence of epilepsy relatives with different types of epilepsy, the concordance rate of seizure types and premonitory seizure types of epilepsy family members, family electroencephalography, the consistency rate of twin epilepsy incidence and chromosomal research of epilepsy families. Therefore, we have come to the consensus that epilepsy runs in families, that is, there is a genetic predisposition to epilepsy, not only for primary epilepsy, but also for secondary epilepsy.

Through the investigation of epilepsy families in China, it is found that the prevalence of first-degree relatives of epilepsy patients is about 1% to 5%. The prevalence in relatives of patients is 5 to 10 times higher than in the normal population.

The prevalence of first-degree relatives in patients with primary epilepsy is higher than that of secondary epilepsy. The prevalence is higher in primary patients than in parents and siblings, and in patients with secondary epilepsy, the incidence is also significantly higher than in the general population.

According to experts, epilepsy is indeed a hereditary disease, including primary and secondary epilepsy, heredity is the main internal cause of epilepsy, from the embryo to the onset of the disease, the damage caused by various factors to the brain is the main external cause of epilepsy.

Epilepsy is genetically predisposed, but not absolute. In real life, seizures caused by genetic factors account for only a small percentage of all epilepsy. As in women during pregnancy, about 1 in 3 patients may have seizures that may worsen.

However, the disease is not passed on to children from generation to generation, so there is no need to worry too much.

The chance of intergenerational inheritance of epilepsy is small, but that doesn't mean it won't happen. There is a certain genetic predisposition to epilepsy. Epilepsy genetics is not absolute, and acquired factors are also crucial.

The decision of whether or not to develop the disease is determined by both internal and external factors. In real life, seizures caused by genetic factors account for only a small percentage of all epilepsy.

1. Acquired factors: The occurrence of epilepsy brings serious harm to the patient's health, and acquired factors are more common causes of the disease. Structural or metabolic abnormalities in the brain caused by acquired factors can produce epileptogenic foci or lower the seizure threshold.

Lesions can be localized or diffuse, quiescent or progressive. This type of epilepsy, called symptomatic (or secondary) epilepsy, is the cause of epilepsy.

2. Genetic factors: genetic predisposition. Numerous studies have proven that epilepsy is related to genetic factors.

Heredity can affect the function of ion channels in cell membranes, reduce the convulsive threshold, and cause neuronal firing. The coincidence rate of twin epilepsy and the study of family EEG showed that epileptic predisposition was inherited in an autosomal dominant manner, and the highest penetrance rate between the ages of 5 and 15 years was the cause of epilepsy.

3. Predisposing factors: There are many seizure factors for epilepsy, but patients must take care of the disease in the process of the disease to avoid the predisposing factors of the disease. Seizures usually occur suddenly and without apparent cause.

Epilepsy**, but there are also some seizures that do have precipitating factors. These triggers may occur periodically, such as seizures related to endocrine factors or menstruation, and other triggers may occur irregularly, which are the causes of epilepsy.

Epilepsy can be hereditary, but there are so many triggers for epilepsy, so many people with epilepsy do not think that epilepsy is a genetic disease. But now people around the world generally believe that epilepsy is inherited.

But not every type of epilepsy is inherited. There are many different types of epilepsy, and most epilepsy is acquired. Some epilepsy does have a genetic predisposition, but hereditary is not always certain.

Studies on twin twins with epilepsy have shown that children with epilepsy have a genetic predisposition, and family analysis and epidemiological surveys of epilepsy patients have shown that the prevalence of epilepsy in relatives with idiopathic epilepsy is as high as 1% in individuals, and the latter is higher than the prevalence of the general population, and the closer the blood relationship with the patient, the higher the prevalence.

The above data show that epilepsy has a genetic predisposition, but this only indicates that people with genetic predisposition have a low seizure threshold, high susceptibility, and are prone to seizures when encountering certain environmental factors, and whether the onset is determined by both internal and external factors.