What are the symptoms of aplastic anemia? How is it treated?

The Department of Hematology of Ping'an Hospital Affiliated to Hebei Medical University is a national key clinical specialty of the Ministry of Health, with strong expert skills and rich clinical experience. If you need help from a hematologist or want to know more, you can consult with a hematologist for free** or call us at 400-0387-130.

This is because of anemia caused by bone marrow damage, and the general causes may be caused by chemicals, radiation, drugs, viral infections, etc., which can be cured by immunosuppression** clear immune cells inside, and then regenerative hematopoiesis.

It is mainly caused by problems with bone marrow hematopoiesis. It can be performed surgically**, the corresponding part is removed first, and then the other part is assisted, or the root cause can be found through blood routine, and then the right medicine can be prescribed, and the spleen can also be removed.

It may be because of irregular diet and rest, it may also be because of psychological infection, it may also be because the immunity of cells has decreased, it may be because of the decrease in blood cells, at this time, you should be hospitalized in time**, or you can insist on taking medication.

Generally speaking, people with chronic aplastic anemia are very sad because the disease is difficult, but we still have to figure out, what is chronic aplastic anemia?

Aplastic anemia, abbreviated as aplasia, is a group of bone marrow hematopoietic failure syndromes caused by a variety of **, characterized by decreased bone marrow hematopoietic cell proliferation and peripheral blood pancytopenia. There are many causes of aplastic anemia, and it is completely possible to find out the symptoms. Aplastic anemia is best achieved by using traditional Chinese medicine, and it is recommended that patients go to see traditional Chinese medicine.

If the patient is severely anemic, the application of Chinese medicine to nourish qi and nourish blood can help improve the tolerance of various tissues and organs to ischemia and hypoxia, so as to help the patient get through the dangerous period. In short, at present, in the absence of ideal conditions for severe aplastic disease, the integration of traditional Chinese and Western medicine is expected to further improve the efficacy.

Aplastic anemia is an acquired stem cell disease. Most patients are in a state in which hematopoietic stem cells in the bone marrow are abnormally attacked by their own T cells due to certain triggers (such as viral infections, special drugs, etc.), and cannot produce hematopoietic cells normally.

**The drug is mainly immunosuppressant, that is, by inhibiting the abnormal immune attack to release and restore the hematopoietic ability of stem cells, about half of the patients with aplastic anemia will take effect after 3-6 months of using immunosuppressants, and some monotherapy with poor effect also need to be combined with a second immunosuppressant**. Young patients with aplastic disease (under 30 years of age) who have a suitable donor will advocate for allogeneic hematopoietic stem cell transplantation, which will have a higher success rate and long-term effect than blood malignancies, and the risk of transplantation is low.

After the age of 30 (especially after the age of 40), the choice of immunosuppressants, aplastic anemia should take into account all aspects, not only to actively cooperate, but also to pay attention to regulate their emotions, to have confidence, positive and optimistic face, if you put too much pressure on yourself every day, in a sad state, it will affect the recovery of the body.

In addition, we should also pay attention to eating more blood-nourishing foods, not picky eaters in terms of diet, meat and vegetables should be reasonably matched, and various nutrients should be supplemented in place, so as to be conducive to the recovery of the body.

After aplastic anemia is diagnosed by a hematology doctor, there are the following ways:

1. Basic**: such as blood transfusion, red blood cell transfusion, platelet transfusion, etc.**;

2. For patients under the age of 50, the first choice is allogeneic hematopoietic stem cell transplantation, because transplantation can completely aplastic aplasia, if the age is not in line or the degree of the disease is mild, immunosuppressants can also be used, and the effect of some patients is also very good. Therefore, aplastic aplastic aplastic should be individualized according to the patient's condition, including age, type and other factors.

Immunosuppressants** are mainly anti-thymoglobulin**, for some patients with good response rates, ** the effect is relatively good, if the patient is not effective, the antithymoglobulin type can be changed**, or directly hematopoietic stem cell transplantation. Hematopoietic stem cell transplantation is a very good measure in aplastic anemia, and in the past, patients would be recommended to use HLA matching homozygous bone marrow transplantation, but in fact, it is difficult to find matching homogeneous transplantation, so now China's haploidentical hematopoietic stem cell transplantation technology is very mature, the effect is also very good, and it has been widely used in aplastic anemia**.

Aplastic anemia is a blood disease, hanging hematology, ** should be based on the blood index, supplemented by bone marrow image, diagnosis and treatment of traditional Chinese and Western medicine, and treatment of both symptoms and symptoms.

In today's society, we can also do a good job of disease prevention through the early symptoms of various diseases. For the disease of aplastic anemia, if we have a certain understanding of its early symptoms, then we can ** the disease early. Let's take a look at its early symptoms.

1. Systemic symptoms.

Often yellow**, pale mucous membranes, fatigue, dizziness, tinnitus, memory loss, loss of appetite, palpitations, shortness of breath.

2. Respiratory tract infection.

Found in the respiratory tract, such as oral mucosa, tonsils, throat, gums, and often causes fever. Infection of the whole body, which can lead to sepsis in severe cases.

3. Oral bleeding.

The bleeding site is extensive and can occur in any organ, common nosebleeds, bleeding gums, menorrhagia, ** and mucosal ecchymosis. Severe hemoptysis, hematemesis, hematuria, melena. A small number of patients have intracranial hemorrhage due to death.

4. Severe cardiomegaly.

Symptoms of severe aplastic anemia include an enlarged heart and a murmur may be heard at the apex. Liver, spleen, lymphadenopathy in general.

The other part is secondary, due to exposure to chemicals (arsenic, bismuth, gold, mercury), radiation (isotopes, such as severe infections, typhoid, hepatitis, kala-azar, sepsis), certain diseases (cancer, uremia, diseases caused by cirrhosis, etc.). )。Some of the above factors have not yet been determined, causing bone marrow damage, resulting in a series of functional changes, leading to hematopoietic dysfunction, pancytopenia, and related symptoms.

Aplastic anemia is a syndrome that causes a decrease in the number or abnormal function of hematopoietic stem cells due to a variety of reasons, causing erythrocytes, neutrophils, and thrombocytopenia, and the symptoms are fatigue and weakness, malaise, pale mucous membranes, palpitations, shortness of breath, headache, tinnitus, fatigue, weakness, and lack of concentration. Aplastic anemia should be removed, supported, and hematopoietic function restored. Acute aplastic aplastic is treated with bone marrow transplantation or immunosuppression such as anti-lymphocyte globulin**, while chronic aplastic aplastic is predominantly androgens**.

Major aplastic anemia is characterized by acute onset, rapid progression, and severe disease. Non-severe aplastic anemia is characterized by slow onset, slow progression, and mild disease.

The symptoms of aplastic anemia are:1There is a possibility of anemia in the body.

2.It may also make the body susceptible to infections. Aplastic anemia is usually caused by a viral infection, but it can also be caused by exposure to radiation, and pancytopenia may occur, which can be performed with hematopoietic stem cell transplantation**.

Prone to yellowish or pale complexion, fatigue, loss of appetite, nausea, belching, bloating, diarrhea, and difficulty swallowing.

It can be improved by:

1. Boil red dates in water, put the red pond after the water is boiled, boil it, and finally put the eggs, 2. Black fungus rock sugar, steamed and eaten, very nourishing It is recommended that you have balanced nutrition, and picky eaters are also prone to anemia.

In addition to the above methods, I know that there is also a simple way to have a cup of Jiuwei Xueying tea every morning and evening to recuperate, double iron and blood supplementation, and have a good improvement effect on anemia symptoms such as yellowing or paleness, dizziness and fatigue.

The clinical manifestations of aplastic disorder are roughly shown in the figure below:

What is aplastic anemia? How to do it**?

Anemia ** first find the cause for the cause **, in addition, it is recommended to eat more lean meat and pork liver, egg yolk, milk, fish and shrimp, shellfish, soybeans, tofu and blood to supplement iron and protein and eat more vegetables and fruits to supplement vitamin C to promote iron absorption. Severe anemia requires blood transfusion**.

Aplastic anemia is not leukemia (commonly known as blood cancer), it is caused by low bone marrow hematopoietic function, and the current medical methods can only use bone marrow transplantation to carry out the first rate, and the first rate is still relatively high.

My friend's child is 6 years old, half a month ago, sudden thrombocytopenia, diagnosed with aplastic anemia, now the ** rate of this disease is not very high, the condition is good to transplant after the effect is better, usually to visit your friend and his baby, you can help where you may be love and support.

1. With immunosuppressants.

2. Promote bone marrow hematopoiesis: androgens, hematopoietic cytokines.

3. Hematopoietic stem cell transplantation.

**The most effective method for aplastic anemia is bone marrow transplantation. At present, bone marrow transplantation is the only way to aplastic anemia, of course, if there is no condition for bone marrow transplantation, that is to say, the economy does not allow or a suitable match is not found, then conservative ** can be considered at this time, if there is anemia, blood transfusion can be given**, if there is thrombocytopenia, platelets can be supplemented, etc., androgens can be used in addition.

Aplastic anemia is a group of bone marrow hematopoietic failure syndromes caused by a variety of **. Symptoms are bleeding, anemia, and infection. **Medications** can also be used, and hematopoietic stem cell transplantation can also be performed.

Aplastic anemia, referred to as aplasia, to put it bluntly, is bone marrow hematopoietic failure, can not make normal blood cells, you can understand the bone marrow as a hematopoietic factory, the factory has hematopoietic workers, and the workers are sick, 10 workers on the day of the index is to create 10 blood cells, for peripheral blood circulation, but these 10 workers, half of the workers are sick and take leave, so only 5 workers are working that day (hematopoiesis), then the day needs 10 blood cells, There are only 5 real circulating in the peripheral blood, so we take conventional **, hormone medication, which can promote bone marrow hematopoiesis, you can imagine that hormone is a leather whip, has been whipping only 5 workers, in order to speed up production, the work index is completed, and then after whipping, 5 workers may exceed the work index of the day, at this time the hemoglobin value of peripheral blood is normal.

However, once the hormone is reduced or stopped, the 5 workers do not want to make blood because they are tired, and it is always the 5 workers who are working, so the hormone medication treats the symptoms but not the root cause, if you want to treat the root cause, we Chinese medicine said that we should cure the 5 sick workers, that is, to improve the function of bone marrow hematopoiesis, so that they can work normally.

Aplastic anemia is a condition in which the bone marrow has hematopoietic failure. **Variety, such as drugs, exposure to harmful substances such as radiation, benzene, hepatitis, etc. The pathogenesis is the body's immune dysfunction, particularly the reduction of bone marrow hematopoietic tissue due to T lymphocyte-mediated immunity enhancement, which is characterized by pancytopenia.

Anemia is the main manifestation of chronic aplastic refraction, and hemorrhage is the main manifestation of acute aplastic refraction. Diagnosis requires a bone marrow smear and bone marrow biopsy, and in some cases, some immunological tests. The bone marrow is hypoproliferative, and biopsy shows a marked decrease in hematopoietic tissue and an increase in adipose tissue.

**Mainly immunization**.

Aplastic anemia is a blood disorder that is caused by a disorder of bone marrow hematopoiesis. The bone marrow is our hematopoietic factory, and the blood includes red blood cells, white blood cells, and platelets, as well as blood cells. It is a hematopoietic disorder, and these cells cannot be made, which causes aplastic anemia.

Aplastic anemia includes general support, as well as the disease itself. Support**, if anemia is a very important ingredient blood transfusion, transfusion of red blood cells, platelets, white blood cells are very low, you can use some leukocyte needles to raise white blood cells, improve anemia and thrombocytopenia, and prevent infection. , mainly aplastic aplasia**, is divided into acute severe aplastic and chronic aplastic aplasia.

At present, patients with severe aplastic disease are more severe, first of all, blood transfusion, platelet transfusion, red blood cell transfusion, after stabilization, consider hematopoietic stem cell transplantation or immunization**, if possible, transplantation, if not available, consider intensive immunosuppression, such as ATG and ALG**. Non-severe aplasia, ** use androgens, cyclosporine these immunization**.