What is Henoch Schonlein purpura nephritis in children and its prevention and treatment

Henoch-Schonlein purpura is a vasculitic syndrome with systemic small vasculitis as the main lesion. 30 to 60% of children can have manifestations of kidney damage. Henoch-Schonlein purpura nephritis is also the most common secondary glomerular disease in pediatrics.

Most children may have hematuria, proteinuria, and casts, accompanied by increased blood pressure or edema, called purpuric nephritis. It is caused by Henoch-Schonlein purpura, and the pathological changes are systemic leukocytofragmented small vasculitis. After diagnosis, it is necessary to stay in bed, control the infection, and be active**, which can be done through adrenocorticosteroids or anticoagulation**.

Heparin is an option for Henoch-Schonlein purpura nephritis**.

(1) **Purpura: One of the main bases for the clinical diagnosis of this disease is that the vast majority of patients have **purpura as the first symptom of allergic purpura nephritis.

Shape. (2) Joint symptoms: 1 2 2 3 patients have joint symptoms, which mostly occur in larger joints, such as knee and ankle joints, followed by wrist and finger joints, which often manifest as tenderness and swelling around the joints, but no redness and heat, and no deformity.

3) Digestive system symptoms: about 2 3 patients have gastrointestinal symptoms, and abdominal cramps are more common. Physical examination shows tenderness in the abdomen.

4) Other manifestations: patients with a history of upper respiratory tract infection may have headache, low-grade fever, and general malaise. Occasionally, nosebleeds or hemoptysis occur, and neurological involvement manifests as headache, behavioral abnormalities, and convulsions. A small number of patients have manifestations of myocarditis.

Henoch-Schonlein purpura nephritis can occur:

1.Rash: It is the first and main clinical manifestation of the disease, which occurs in the distal extremities, buttocks and lower abdomen, with a multisymmetrical distribution, slightly higher than the ** surface, and may have an itchy sensation, which gradually subsides after 1 2 weeks, and often appears in batches.

The interval from purpura to renal damage is less than 2 weeks.

2.Joint symptoms: It is a common symptom of the disease, characterized by multiple, non-migratory, and arthralgia that occurs mostly in the ankle joint.

3 Gastrointestinal symptoms: often seen, mainly manifested as abdominal pain, abdominal discomfort and diarrhea. Common sites are the umbilicus and lower abdomen. Abdominal pain can sometimes manifest as paroxysmal colic.

4 Others: lymphadenopathy, hepatosplenomegaly and neurological involvement such as headache, convulsions and abnormal behavior.

In daily life, pay attention to whether there is any suspicious food or foreign body contact that causes allergies before the rash appears, and avoid re-contact. Avoid eating foreign proteins such as seafood to prevent re-allergies and aggravation of the condition. Pay attention to cold and warmth, prevent colds, pay attention to exercise, enhance physical fitness, and improve the body's ability to resist diseases.

**Rash, there is a phenomenon of patches. The mucous membrane of the gastrointestinal tract is prone to appearance (this is not visible to the naked eye). The rest are kidney disease-related symptoms.

The symptoms are changes in the urine, and the symptoms of protein occult blood in the urine routine are not only the symptoms of purpura, but also swelling and blood pressure.

There is a typical **purpura, with arthralgia, abdominal pain and melena, a rash appears, and hematuria or proteinuria appears 1 to 4 weeks after the rash appears.

Purpura is a disease that fundamentally repairs the kidneys, and how long has the patient been ill, protein in the urine is a few pluses. I'm a nephrologist and I need to know about the patient's condition.

Henoch-Schonlein purpura nephritis, the main clinical manifestations are hematuria and proteinuria in the kidneys, and hypertension, edema, azotemia, and even acute or chronic renal failure can occur. These symptoms can run through the entire course of purpuric nephritis, but most of them occur within half a month to a month after purpura, and very few cases can appear up to a year after purpura, so some cases can only be detected by urinalysis. Except for the kidneys.

In addition to manifestations, gastrointestinal symptoms and joint symptoms may occur. Gastrointestinal symptoms are mainly manifested as abdominal pain, blood in the stool, nausea, vomiting and other discomforts.