Can atorvastatin be taken for a long time?

Statins, drugs to control LDL cholesterol, prevent and control stable atherosclerotic plaques, can be taken for a long time, but regular blood lipids, cardiac enzyme spectrum and liver function tests are required.

Avastatin is a hypolipidemic drug, long-term use has an impact on the liver, should be taken for a period of time, check whether the liver function is normal, if the blood lipids are normal, you can stop taking it.

Who needs to take tortavastatin and other statins for a long time, listen to what the doctor says.

Atorvastatin and pitavastatin are both members of the statin family, and both belong to the third generation of statins, what does it mean?

Statins are divided into the first generation, such as simvastatin and lovastatin; second-generation, such as fluvastatin; The third generation, such as atorvastatin, rosuvastatin, pitavastatin. Third-generation statins have a poor duration of action, unlike the first and second generations, which must be taken at night, and third-generation statins can be taken during the day and at night. Moreover, the third-generation statin has a stronger lipid-lowering effect and is a strong lipid-lowering drug.

These atorvastatins and pitavastatins both belong to the third generation of statins, and for the vast majority of patients, the two statins are not much different. It can be used to reduce scorbability, reduce low-density lipoprotein, lower cholesterol, and lower triglycerides; It can increase blood lipids and high-density lipoprotein. Both statins can stabilize plaques with anti-inflammatory, prevent plaque rupture, prevent blood clots, prevent myocardial infarction, and prevent cerebral infarction.

But after all, it is a different drug, and there are subtle differences:

The most common adverse reactions of statins are muscle damage, abnormal liver function, and increased blood glucose.

Pitavastatin has a lower risk of diabetes.

Atorvastatin has a lower effect on liver function than pitavastatin.

Atorvastatin has a relatively low effect on muscles than pitavastatin.

All statins cannot 100% avoid this kind of occurrence, so whether you are taking atorvastatin or pitavastatin, you need to monitor*** and have regular checks.

In addition to the difference in ***, there is also a slight difference between the two statins in terms of being affected by other drugs.

Atorvastatin is metabolized by P4503A4, which will conflict with some anti-inflammatory drugs and increase the drug***, so try to avoid simultaneous use. For example, ritonavir, clarithromycin, grapefruit juice, etc., for atorvastatin, are drugs that will increase blood concentration, and should be avoided as much as possible. Pitavastatin is almost not metabolized by CYP450, and drug interactions are small and the incidence is low when combined.

So pitavastatin is not affected by these drugs or foods and is safer than drugs.

But for the vast majority of patients, there is not much difference between the two drugs, because there is no absolutely safe drug. During the period of taking, it is necessary to monitor the drug for a long time, and adjust the regimen in time, reduce, change or stop the drug.