Can simvastatin tablets replace atorvastatin calcium tablets

OK. The following is a comparison of the indications of the two.

Simvastatin tablets.

Indications】 Hyperlipidemia.

For patients with primary hypercholesterolemia, including heterozygous familial hypercholesterolemia hyperlipidemia or mixed hyperlipidemia, when dietary control and other non-drug ** are not ideal, combined with dietary control, this product can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides, and can increase high-density lipoprotein cholesterol, thereby reducing the ratio of low-density lipoprotein cholesterol to high-density lipoprotein cholesterol and total cholesterol to high-density lipoprotein cholesterol.

For patients with homozygous familial hypercholesterolemia, combined with dietary control and non-dietary**, this product can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B.

Coronary heart disease. For patients with coronary heart disease and hypercholesterolemia, this product is suitable for:

Reduces the risk of death.

Reduces the risk of death from coronary heart disease and non-fatal myocardial infarction.

Reduces the risk of stroke and transient cerebral ischemia.

Reduces the risk of cardiac revascularization surgery (coronary artery bypass grafting and percutaneous transluminal coronary angioplasty).

Slowing the progression of coronary atherosclerosis involves reducing the formation of new lesions and total blockages.

atorvastatin calcium tablets.

Indications] Patients with primary hypercholesterolemia, including familial hypercholesterolemia (heterozygous type) or mixed hyperlipidemia (equivalent to IIA and IIB types of Fredrickson classification), if the diet and other non-drug ** effects are not satisfactory, the application of this product can increase their total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides.

In patients with homozygous familial hypercholesterolemia, atorvastatin calcium may be used in combination with other lipid-lowering drugs or alone (when no other means are available**) to lower total cholesterol and LDL cholesterol.

Atorvastatin's *** is relatively smaller.

Simvastatin is comparatively cheaper.

It doesn't matter, it's all statins.

How about atorvastatin calcium tablets

Atorvastatin calcium tablets are mainly used to help alleviate symptoms such as high cholesterol and sepsis, and he is still used more in our medicines, which is a Western prescription drug, so let's take a look at atorvastatin calcium tablets.

How about atorvastatin calcium tablets

Atorvastatin is a kind of Western medicine, prescription drug that has a relatively good lowering effect on cholesterol and blood lipids, and some of the ingredients contained in it have a certain inhibitory effect on reducing the cholesterol content in the body and the high fat of the body, so it still has a good effect, but when we use it, we must control the daily standard diet, and try to carry out a relatively low cholesterol diet. Moreover, during the use of this calcium tablet, it is also necessary to pay attention to maintaining a reasonable diet.

Some drugs may need to be taken before or half an hour after meals when used, and this calcium tablet does not need to be limited by this time, as long as it is used according to the number of times, it can help control the content and level of blood esters in the human body, and the effect is relatively fast, but it needs to adhere to the course of treatment for a long time, because in this way it can maintain its effect.

Atorvastatin calcium tablets are likely to have adverse reactions when used, mainly due to symptoms such as stomach flatulence or stool blockage, and may also cause loss of appetite or indigestion, which may lead to gastrointestinal discomfort.

Summary. Hello Atorvastatin calcium tablets include dizziness, nausea, myalgia, stomach upset, general reactions such as rashes, liver damage, rhabdomyolysis, etc. In the process of taking atorvastatin, there will be mild adverse reactions, mainly including headache, dizziness, nausea, stomach upset, rash and other reactions, most of which do not need to be stopped, and the symptoms may be gradually relieved.

Atorvastatin is harmful to the liver, can lead to increased aminotransferase levels, and even severe liver failure, which may be related to the patient's sensitivity to the drug. Atorvastatin causes muscle damage, and in severe cases, rhabdomyolysis can occur, which can manifest as a severe illness with elevated levels of creatine kinase, and myoglobin blockage of the renal tubules can lead to renal failure. In the process of taking atorvastatin, it is necessary to pay attention to the adverse reactions of the drug, and if there are uncomfortable symptoms, it is necessary to go to the hospital in time for treatment, and standardize the diagnosis and treatment under the guidance of the physician.

Hello Atorvastatin calcium tablets include dizziness, nausea, myalgia, stomach upset, general reactions such as rashes, liver damage, rhabdomyolysis, etc. In the process of taking atorvastatin, there will be mild adverse reactions, mainly including headache, dizziness, nausea, stomach upset, rash and other reactions, most of which do not need to be stopped, and the symptoms may be gradually relieved. Atorvastatin is harmful to the liver, can lead to increased aminotransferase levels, and even severe liver failure, which may be related to the patient's sensitivity to the drug.

Atorvastatin causes muscle damage, and in severe cases, rhabdomyolysis can occur, which can manifest as a severe illness with elevated levels of creatine kinase, and myoglobin blockage of the renal tubules can lead to renal failure. In the process of taking atorvastatin, it is necessary to pay attention to the adverse reactions of the drug, and if there are uncomfortable symptoms, it is necessary to go to the hospital in time for treatment, and standardize the diagnosis and treatment under the guidance of the physician.

Hello Avastatin, commonly known as atorvastatin calcium, is a commonly used hypolipidemic drug. Atorvastatin calcium adverse reactions include: The most common adverse reactions of taking atorvastatin calcium are:

gastrointestinal upset, others include headaches, rashes, dizziness, blurred vision, and dysgeusia; Occasionally, it can cause reversible elevation of blood aminotransferases, so liver function should be monitored; Rare adverse reactions include impotence and insomnia; Rare adverse reactions include myositis, myalgia, rhabdomyolysis, which is manifested as muscle pain, fatigue, fever, and accompanied by elevated blood creatine phosphokinase, myoglobinuria, etc., rhabdomyolysis can lead to renal failure, but rare. The combination of atorvastatin calcium with immunosuppressants, folic acid derivatives, niacin, gemfibrozil, erythromycin, etc., can increase the risk of myopathy;

1. Statin maintenance after interventional surgery is a must, and long-term or even lifelong medication can greatly reduce the probability of recurrence of cardiovascular events.

Patients who are approved to take statin drugs for a long time do not need to have their liver function tested, and the effects of atorvastatin on the liver only need to be paid attention to for the first 1-3 months of taking the drug, after which it is relatively safe.

3.Atorvastatin can improve kidney function, which other statins cannot4Statins have an effect on muscle, but atorvastatin is mild.

Is the doubt solved?

At a dose of 10mg, the incidence of rhabdomyolysis is very low under normal circumstances, but it does not include poor liver function or the combination of multiple drugs, if it is indeed muscle pain, you can go to the hospital to check whether the muscle enzymes are normal, rhabdomyolysis is generally accompanied by abnormal urine test or kidney function. It should also be ruled out whether there is a problem of joints. Because the ** of statins after stent surgery is still quite critical.

Answer: atorvastatin calcium tablets can be eaten for a long time, long-term use is as a secondary prevention of patients with myocardial infarction or cerebral infarction, it needs to be taken for a long time, long-term use can reduce blood lipids and stabilize plaques in blood vessels, stabilize the formation of plaques, atorvastatin calcium is mainly used for high cholesterol and high triglycerides, and can also reduce the level of blood lipids for low-density lipoprotein and high-density lipoprotein.

In the process of use, it is generally taken 10mg before bedtime, if the cholesterol and triglycerides are high, the dose can be increased to 20 mg, the maintenance amount is generally between 10 mg and 20 mg, and the liver function should be rechecked for three to six months during the long-term taking period.

Statins have a serious *** can cause rhabdomyolysis, manifested as muscle pain, to determine whether your mother has joint pain, it is recommended to go to the hospital for a check-up.

Atorvastatin calcium tablets is a drug that inhibits lipid cholesterol synthesis and regulates blood lipids, and achieves the effect of lowering low-density lipoprotein cholesterol and increasing high-density lipoprotein cholesterol by inhibiting cholesterol synthesis in the liver. The reduction of cholesterol levels can reduce the occurrence and development of atherosclerosis for ischemic diseases including coronary heart disease, cerebrovascular disease, and peripheral atherosclerotic diseases. For pre-existing atherosclerotic plaques, atorvastatin** can stabilize plaques from unstable to long-term use.

I just suffer from coronary heart disease, and the effect of Lipitor atorvastatin calcium tablets is still good, and the time of taking it makes me very satisfied, as long as I take it at any time of the day, I don't have to worry about when I should eat it, or when I shouldn't eat it.

Atorvastatin and pitavastatin are both members of the statin family, and both belong to the third generation of statins, what does it mean?

Statins are divided into the first generation, such as simvastatin and lovastatin; second-generation, such as fluvastatin; The third generation, such as atorvastatin, rosuvastatin, pitavastatin. Third-generation statins have a poor duration of action, unlike the first and second generations, which must be taken at night, and third-generation statins can be taken during the day and at night. Moreover, the third-generation statin has a stronger lipid-lowering effect and is a strong lipid-lowering drug.

These atorvastatins and pitavastatins both belong to the third generation of statins, and for the vast majority of patients, the two statins are not much different. It can be used to reduce scorbability, reduce low-density lipoprotein, lower cholesterol, and lower triglycerides; It can increase blood lipids and high-density lipoprotein. Both statins can stabilize plaques with anti-inflammatory, prevent plaque rupture, prevent blood clots, prevent myocardial infarction, and prevent cerebral infarction.

But after all, it is a different drug, and there are subtle differences:

The most common adverse reactions of statins are muscle damage, abnormal liver function, and increased blood glucose.

Pitavastatin has a lower risk of diabetes.

Atorvastatin has a lower effect on liver function than pitavastatin.

Atorvastatin has a relatively low effect on muscles than pitavastatin.

All statins cannot 100% avoid this kind of occurrence, so whether you are taking atorvastatin or pitavastatin, you need to monitor*** and have regular checks.

In addition to the difference in ***, there is also a slight difference between the two statins in terms of being affected by other drugs.

Atorvastatin is metabolized by P4503A4, which will conflict with some anti-inflammatory drugs and increase the drug***, so try to avoid simultaneous use. For example, ritonavir, clarithromycin, grapefruit juice, etc., for atorvastatin, are drugs that will increase blood concentration, and should be avoided as much as possible. Pitavastatin is almost not metabolized by CYP450, and drug interactions are small and the incidence is low when combined.

So pitavastatin is not affected by these drugs or foods and is safer than drugs.

But for the vast majority of patients, there is not much difference between the two drugs, because there is no absolutely safe drug. During the period of taking, it is necessary to monitor the drug for a long time, and adjust the regimen in time, reduce, change or stop the drug.