Does rabies cause death in people

Rabies, also known as hydrophobia, is an acute zoonotic infectious disease caused by the rabies virus. It is more common in dogs, cats and other animals, and humans are mostly infected by bites of sick animals, and can also be infected by poisonous saliva contaminating wounds, mucous membranes and even conjunctiva. Unfortunately, humans are generally susceptible to the rabies virus, with an average incidence of 15 to 20 per cent of people bitten by a sick dog and not vaccinated against rabies, and in some places as high as 70 per cent.

Rabies is easily transmitted, the consequences are severe, and it is difficult in some ways to be even more troublesome than AIDS.

The clinical manifestations of rabies can be divided into four stages.

Incubation period (about 4-6 weeks on average, the shortest and longest range can be up to 10 days - 8 months).

Depending on the individual's constitution, the incubation period can range from a few days to several years, and the infected person does not have any symptoms during the incubation period.

Prodromal phase Infected people begin to develop symptoms such as general malaise, fever, tiredness, restlessness, pain at the bite site, and paresthesias.

Excitable period Human beings: patients have a peak of various symptoms, such as mental stress, general spasms, hallucinations, delirium, fear of light, sound, water, wind and other symptoms, so rabies is also known as hydrophobia, and patients often suffocate to death because of throat spasms.

Coma phase If the patient is able to survive the excitatory period, the patient will enter the coma phase, in which the patient is in a deep coma, but the symptoms of rabies are no longer obvious, and most patients who enter this stage eventually collapse and die.

Pathology After the rabies virus enters the human body, it first infects muscle cells, spends the incubation period in muscle cells, and then enters nerve cells through acetylcholine receptors between muscle cells and nerve cells, and then enters the spinal cord along the same pathway, and then enters the brain, and does not delay blood spread. The virus infects the hippocampus, cerebellum, brainstem and even the entire central nervous system in the brain, and replicates in large quantities in gray matter, extending the nerve down to the salivary glands, cornea, nasal mucosa, lungs, ** and other parts. The main damage of rabies virus to the host comes from endosomes, that is, eosinophilic particles formed by the accumulation of its discarded protein shell in cells, which are widely distributed in the patient's central nervous system cells and are also an indicator of laboratory diagnosis of the disease.

When a person is bitten by a rabies dog infected with the rabies virus, the virus becomes infected through the wound and multiplies in the surrounding tissues. To a certain extent, it follows the peripheral nerves to the central nervous system and the brain. The rate of introduction of the virus is about 3 nanometers per hour.

When the virus reaches the nerve roots on the dorsal side of the spinal cord, it begins to multiply in large numbers, spreading throughout the central nervous system within 24 hours. Then the symptoms appeared. Symptoms are divided into three stages; Prodromal, manic, and paralytic phases.

The prodromal phase is the initial stage of the disease, with headaches, restlessness, and fear. The manic phase is the euphoria phase, and the symptoms unique to rabies may appear, such as hydrophobia; The paralysis period is when the patient passes through the manic period and turns manic to quiet and unresponsive, and the family members will generally think that the condition is improving, but in fact, the cranial nerves and limb nerves will soon be paralyzed, and eventually die due to respiratory and circulatory failure.

After the dog is infected with the rabies virus, once the attack occurs, the dog will die 100%, so we must be vigilant at ordinary times, and during the dog's juvenile years, it must be vaccinated against rabies, and the rabies vaccine needs to be given once a year. If you notice that your dog has symptoms of a rabies attack, isolate your dog immediately to avoid transmitting the rabies virus to other animals or humans.

After a dog is infected with the rabies virus, once the disease develops, then the dog will die 100%. Be sure to give the dog a rabies vaccine in time when the dog is a puppy to avoid the dog being infected with rabies and make the dog grow up healthily.

During the puppy period, the dog's resistance is very fragile, and it is easy to be infected with various diseases and rabies virus, in addition to vaccinating the dog during the puppy period, and then it is necessary to get a rabies vaccine every year. When breeding, avoid the dog from touching things that carry the rabies virus.

Unless the person has been bitten by another mad animal, it can't be.

Only when the virus enters the central nervous system, it begins to multiply in large quantities, and the reproduced virus will enter the salivary glands from the brain, and then it is infectious, and this kind of encephalomyelitis attack animals, from the infectious point of calculation, within 3-5 days there will be a loss of appetite and other abnormalities that the owner can feel, and within 5-7 days, there will be a variety of obvious abnormalities that outsiders can see at a glance, and they will inevitably die or die within 10 days.

Therefore, if the animal is still normal after 5 days, the risk of infection can be actually ruled out, and if there is no abnormality after 7 days, the risk of infection can be ruled out, and the risk of infection can be absolutely ruled out if there is no death or dying on the 10th.

It is impossible for an animal to die and a person to die of rabies, unless it is a second exposure, that is, the person dies from the bite of another mad animal.

1. The pathogen and transmission route of rabies

Dogs will not die of rabies, first of all, we must understand its pathogen and the route of infection. Rabies is caused by a virus and is often spread through the saliva of dogs. When a dog infected with the rabies virus bites a person, the virus will enter the body through saliva, so it is important to treat the dog's wound and get vaccinated against rabies promptly.

2. Resistance of dogs to rabies

Dogs will not die of rabies, and because dogs have a certain function of immunity from the epidemic. When a dog is infected with the rabies virus, its own immune system produces antibodies to fight the virus. If the dog's immune system is strong enough to effectively screen for the virus and produce enough antibodies, then the virus will be eliminated and the dog will be able to**.

3. The best method of dog rabies

In addition to autoimmune function, dogs will not die of rabies because there are effective methods. Once a dog is diagnosed with rabies, it can receive an antiviral** or immune boost**. The rabies virus can be neutralized with drugs that target the virus** and prevent further spread of the virus.

4. The importance of rabies prevention and control

The prevention and treatment of rabies is very important, not only to protect the health of dogs, but also to ensure the health of humans. When a dog is infected with the rabies virus, it not only causes the dog to get sick, but also can spread the virus to people through bites and other means, threatening human health. Therefore, it is very important to vaccinate against rabies in time and reasonably prevent dog bites.