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1. Overview. Canine distemper – also known as canine distemper – is a pathogenic virus. It mainly infringes on dogs and ferrets.
It belongs to paramyxovirus. The incubation period after infection is short, and the mortality rate is about 50%. The attenuated virus can be used as a live vaccine for the reproduction of chicken embryo fibroblasts and dog kidney cells in cultured cells.
To study the viability and environment of canine plague virus, and to strengthen the management and prevention of canine virus transmission routes.
2. Pathogenesis.
The natural route of infection is mainly through the upper respiratory tract. After CDV invades the body through the nasal, pharyngeal and upper respiratory tract, it first proliferates in the nearby lymph nodes and tonsils, proliferates in tissue macrophages within 24 hours, and spreads to the whole cell, from the regional lymphatic vessels to the tonsils and bronchial lymph nodes. After infection2 4d, the virus multiplies in the tonsils and retropharyngeal lymph nodes and bronchial lymph nodes.
4 After 6 days, CDV proliferates in spleen lymph follicles, lamina propria propria of the stomach and small intestine, mesenteric lymph nodes, and liver astrocytes, and the animals show initial elevated body temperature and leukopenia. Viremia appears in the first week after infection, and with the help of blood circulation, CDV spreads to the lymphoid organs, bone marrow, and the membranes of the epithelial structures of the whole body, and all secretions of the body begin to excrete outward. Antibodies develop rapidly in 50% of dogs after infection, which can be detected at 8 to 9 days.
After 8 9 days of infection, the virus further spread to epithelial tissues and CNS tissues, and all secretions of the body began to excrete outward, even dogs in the subclinical infection stage began to shed toxins. Dogs with good immune levels had sufficient CDV antibodies 14 days after infection, cell-mediated cytotoxicity cleaned up the virus from most tissues, animals did not show clinical symptoms of canine distemper, and dogs with poor immune levels spread the virus to their tissues in 9 14 days after infection, including **, endocrine glands, gastrointestinal epithelium, respiratory epithelium, genitourinary epithelium, etc., showing clinical symptoms of virus invasion of multiple systems. In brain tissue, CDV is characterized by the activation of blood vessel wall cells, which in turn causes glial cell reactions, demyelinating encephalitis, and death by neurological symptoms 3 to 4 weeks after infection.
3. Environmental survival.
1. The environmental viability of canine plague virus is not strong, it can only survive for a few hours in a dry environment at room temperature, it can survive for several weeks in a low temperature (a few degrees above zero) and dark environment, and it can survive for several years in a frozen and dark environment.
2. It can be inactivated by conventional disinfection and cleaning.
3. The main way of infection is to inhale the suspended particles coughed up by the sick dog and contact with fresh secretions (within 30 minutes), so basically the infection will occur only if it is in close contact with the sick dog.
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Why do you get canine plague?
Canine plague, also known as canine parvovirus, is a viral disease caused by canine parvovirus. So why do you get canine plague? The following will elaborate on the aspects of virus transmission and host susceptibility.
1. Virus transmission
Canine plague is a disease caused by the transmission of canine stampanovirus, which can be present in the air for several hours or can be transmitted through body fluids, vomit, feces, etc. In areas with high virus content, such as pet group Kaiwu hospitals, foster care centers, etc., canine plague spreads faster. However, it is only in the somatic cells of dogs that the virus can replicate and further infect the dog.
2. Host susceptibility
All dog breeds can be infected with canine parvovirus, which can cause canine plague, although puppies are more susceptible. The age of initial infection with canine plague is generally between 6 weeks and 6 months, which is because their natural immunity has not yet been fully established. In addition, they are susceptible to infection due to their more exposure to environments and companions.
Adult dogs can also be infected with canine plague, but the disease is generally not as severe as that of puppies.
3. Ways to resist canine plague
In order to avoid the occurrence of canine plague, dog owners can take some precautions, such as vaccinating their dogs against canine plague normally. The vaccine is usually given for the first time at 6 weeks of age and at least every 4 weeks thereafter until it is 1 year old. In addition, regular physical examinations, disinfection, and isolation of new dogs are all effective ways to prevent canine plague.
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1.Canine plague is caused by the canine plague virus and is a highly contagious infectious disease.
2.After the dog is infected with canine plague virus, it will have depression, decreased appetite, abnormal body temperature, purulent nasal discharge, vomiting, diarrhea, blood in the stool, and convulsions and salivation in the later stage.
3.The mortality rate of canine plague is very high, once the dog is found to have the above symptoms, immediately take the dog to the hospital for examination**, use antiviral drugs such as interferon and inhibitory protein**, and use amoxicillin, penicillin and other drugs to prevent secondary bacterial infection.
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1.Dog plague is a highly contagious viral infection caused by canine distemper virus infection, which is widely present in the eye and nose secretions of sick dogs, and also contaminates the air around them.
2.If the dog is normal or lacks the relevant immunity, it is possible to be infected with the canine distemper virus after being exposed to the relevant infectious agent, which can lead to the disease.
3.After a dog is infected with canine distemper virus, it usually shows related symptoms within the fourth day, mainly including sneezing, runny nose, cough, fever, etc.
4.At the same time, after 1-2 days, the eyes secrete purulent discharge, purulent nasal discharge.
5.In the later stage, there will be nasal blockage, nasal scratching, and exhalation of foul-smelling gas, which is recommended to be taken to the pet hospital for further examination and**.
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Canine plague is a highly contagious infectious disease caused by canine distemper virus, which is highly contagious and can have a mortality rate of more than 80%. At the beginning of the symptoms of canine distemper, the dog's body temperature is as high as 39 5 41 degrees Celsius, loss of appetite, depression, watery discharge from the eyes and nose, sneezing, and diarrhea. In the next 2 to 14 days, the body temperature rises again, cough, purulent nasal discharge, purulent eye feces, and it is already the middle stage of canine plague.
At the same time, secondary gastrointestinal diseases, vomiting, diarrhea, and loss of appetite. Highly depressed and lethargic. In the later stage of the onset of canine distemper, there will be typical neurological symptoms, foaming at the mouth, convulsions, at this time it is generally difficult to **, but there are some successful cases**.
The disease can occur all year round, but it is more common in winter and spring. The disease has a certain cyclical nature, with a pandemic every three years. Dogs of all ages, sexes, and breeds can be infected, but minor puppies are most susceptible.
Purebred dogs and police dogs are more susceptible than native dogs, and they have a severe response and a high mortality rate. The most important sources of infection are nasal and eye secretions and urine. It has been reported that dogs infected with canine plague virus still have virus excretion in urine after 60-90 days, so urine is a very dangerous source of infection, and the main transmission route is direct contact between sick dogs and healthy dogs, and it can also be infected through respiratory tract through airborne droplets.
Once a dog in the same room is found to have canine plague, no matter how strict protective measures are taken, it cannot avoid the infection of dogs living in the same room.
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Canine distemper is one of the deadliest viral infectious diseases in dogs, usually due to close contact with sick dogs, or contact with sick dogs or carrying dog secretions, or it may also be shared with sick dogs, which may cause the occurrence of canine distemper, the main characteristics of canine distemper are fever, vomiting, high fever, runny nose, lung infections and so on.
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There are so many ways of infection. It is usually in contact with a sick dog.
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Canine distemper mainly infects canids, and the transmission channel is mainly through direct contact with sick animals, but also through air or food, and is not a zoonotic disease. You can try Dora Xiaomeng disinfectant is a physical sterilization, does not contain any chemical ingredients, safe and healthy to drink, has a 100% killing effect on bacteria, fungi and viruses, and has an authoritative test report as evidence, or a national invention patent product! There are no bacteria and viruses on the pet's body, and when it is clean, there will be no parasitic environment for parasites!
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Canine distemper, commonly known as canine distemper, is a serious canine disease that mainly affects puppies. The causative agent is canine distemper virus. Sick dogs are characterized by biphasic fever, rhinitis, severe digestive tract disorders, and respiratory tract inflammation.
Encephalitis can occur in a few cases. Dog breeds such as sled dogs, which are adapted to live in cold areas, have a high mortality rate from this disease.
All kinds of secretions, excretions (nasal juice, saliva, tears, pericardial fluid, pleural fluid, ascites and urine) and blood, cerebrospinal fluid, lymph nodes, liver, spleen, spinal cord and other organs of the virus source dogs contain a large number of viruses, and can be excreted to the outside world with respiratory secretions and urine. Healthy dogs are infected through the respiratory or digestive tract through direct contact with sick dogs or through contaminated air or food. In addition to puppies being the most susceptible to infection, foxes and minks among fur-bearing animals are also very susceptible to canine distemper.
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Canine plague infection, mainly sick dogs and poisonous dogs, special attention should be paid to the fact that some dogs that have had canine plague, **, can be detoxified to the outside world for a long time, become a source of infection that is not noticed by people, canine plague transmission routes mainly include water, food, air, etc., canine plague is highly contagious, animals raised in the same environment, as long as one is infected, the other no matter what kind of isolation measures are taken, it is inevitable to infect each other, which is why sometimes dogs do not leave home, the reason why canine plague is infected.
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