What does hemolysis mean, what does it mean to draw blood hemolysis

Hemolysis: Red blood cells break down and hemoglobin escapes called red blood cell lysis, referred to as hemolysis. It can be caused by a variety of physicochemical factors and toxins.

In vitro, such as hypotonic solution, mechanical strong oscillation, sudden low temperature freezing (-20 -25) or sudden thawing, excessive acid or alkali, as well as alcohol, ether, saponine, choline salts, etc. can cause hemolysis. The isotonic solution of human plasma is a solution, and the red blood cells are lower than the solution, and the red blood cells are ruptured due to water infiltration, red blood cell expansion, and hemoglobin escapes. In vivo, hemolysis can be caused by the invasion of hemolytic bacteria or some snake venom, antigen-antibody reactions (such as transfusion of incompatible blood), various mechanical injuries, intrinsic (membrane, enzyme) defects in red blood cells, and certain drugs.

Hemolytic bacteria, such as some hemolytic streptococci and Bacillus perfringens, can cause sepsis. Plasmodium destroys red blood cells and some hemolytic snake venoms contain lecithinase, which converts the lecithin of plasma or red blood cells into lysolecithin, which breaks down the red blood cell membrane. The blood types of the parents are A and B, and the woman needs to undergo a hemolysis test to observe whether the baby's development is normal during the non-chen period.

When cells are damaged, mitochondria and cell fluid in the cells are dissolved into the blood.

It is the destruction of the body's red blood cells.

Question 1: What is the risk of specimen hemolysis during blood collection Improper operation Among the 50 specimens with hemolysis, most of them are related to difficulty in blood drawing. There were 25 cases of hypovolemia and 10 cases of neonates.

1) When collecting blood samples from these patients, the operator mostly ties the tourniquet for too long and too tightly, and vigorously pats the puncture site. (2) Draw the empty needle to 510ml in one yard and wait for the blood to enter the syringe by negative pressure. (3) Due to the poor fixation of the needle, the bevel of the needle is attached to the blood vessel wall, resulting in a large amount of foam mixed in the blood.

4) The operator did not follow the operating procedures and slowly injected the blood along the blood vessel wall, but injected it too quickly. This causes foam to be injected into the test tube along with the blood, resulting in hemolysis. (5) The operator shakes the specimen bottle too hard, causing hemolysis.

The specimen container is unqualified, the quality of the empty needle is not up to standard, and the sealing is not good, resulting in hemolysis. Specimen freezing The specimen is placed on the windowsill and is not sent for inspection in time, and the temperature is too low to cause freezing.

Question 2: What does it mean to say that the appearance of the specimen is mild hemolysis when the blood is drawn "The blood draw says that the appearance of the specimen is mild hemolysis" means that the red blood cells have mild delayed leakage and lysis.