Drug, what is camiacin?

Amika sulfate is an aminoglycoside antibiotic. This product has a good effect on most Enterobacteriaceae bacteria, such as Escherichia coli, Klebsiella, Enterobacteriaceae, Proteus, Shigella, Salmonella, Citrobacterium, Serratia, etc., and also has a good effect on Pseudomonas aeruginosa and other Pseudomonas, Acinetobacter, Alcaligenes, etc.; It also has good antibacterial effect on Neisseria meningitidis, Neisseria gonorrhoeae, Haemophilus influenzae, Yersinia spp., Campylobacter fetus, Mycobacterium tuberculosis and some non-tuberculous mycobacterial species, and its antibacterial activity is slightly lower than that of gentamicin. The most prominent advantage of this product is that it is stable with aminoglycoside passivation enzymes produced by many intestinal gram-negative bacilli, and will not lose antibacterial activity due to the passivation of such enzymes.

Among the 12 passivation enzymes that have been isolated so far, this product can only be passivated by AAC (6'), and AAD (4') and APH (3') can occasionally lead to moderate resistance of bacteria to this product. About 60% of clinically isolated Enterobacteriaceae bacteria are resistant to aminoglycosides such as gentamicin, tobramycin and netemicin 70% are still sensitive to this product. In recent years, there has also been an increase in amikacin-resistant strains in gram-negative bacilli.

In addition to the good antibacterial effect on methicillin-susceptible strains in Staphylococcus spp., this product is mostly resistant to Streptococcus pneumoniae, streptococci and enterococci in various groups. This product is ineffective against anaerobic bacteria. The mechanism of action of this product is to act on the 30S subunit of bacterial ribosomes and inhibit the synthesis of proteins by bacteria.

Amikacin often obtains synergistic antimicrobial effects when combined with semisynthetic penicillins or cephalosporins. Star Bar —-—

It is amikacin, an aminoglycoside antibiotic, which inhibits a variety of bacilli and is mainly used for gentamicin-resistant and kanamycin infections.

In addition: this product is suitable for bacteremia, bacterial endocarditis, sepsis (including neonatal sepsis), respiratory tract infection, bone and joint infection, central nervous system infection (including meningitis), **soft tissue infection, biliary tract infection, intraperitoneal infection (including peritonitis), burns, Post-operative infections (including post-vascular surgical infections) and ** urinary tract infections, etc.

It should be noted that amikacin should not be used in treatment-naïve cases of isolated urinary tract infection.

Hope it helps. Wishing you or your family a speedy day**.

It is mainly used for various infections caused by gram-negative bacilli such as Escherichia coli, Proteus and Pseudomonas aeruginosa resistant to gentamicin and kanamycin.

Synonyms of amikacin: amikamycin, amikacin sulfate, ankacin, lixin, amikamycin, amikacin, amikacin, amamkamycin monosulfate, amikamycin disulfate, amikamycin sulfate.

Common name: amikaci ulfateforinjection Chinese pinyin:

zhusheyongliusuana'The main ingredient of this product is amikacin sulfate, and its structural formula is: molecular formula: C22H43N5O13·NH2SO4 (N=

Common name: amikacin sulfate for injection Trade name: English name:

amikaci ulfateforinjection Chinese pinyin: zhusheyongliusuana'The main ingredient of this product is amikacin sulfate, whose chemical name is O-3-amino-3-deoxy--D-glucopyranosyl-(1 6)-O-[(6-amino-6-deoxy--D-glucopyranosyl-(1 4)]-N-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptomyamine sulfate, and its structural formula is: molecular formula:

c22h43n5o13·nh2so4(n=

Amikacin sulfate is also called Dinan Kana.

The main effects of amikacin: infections of the lower respiratory tract, urinary tract, abdominal cavity, ** and soft tissues, bones and joints, etc., burns, meningitis caused by sensitive bacteria. Empiric in suspected Pseudomonas aeruginosa infection, cystic fibrosis, and immunocompromised patients**.

Topical lotions are used for severe traumatic infections caused by susceptible bacteria. Eye drops are used for conjunctivitis, keratitis, etc. caused by sensitive bacteria.

For the antibacterial effect of antibiotics on some Gram-positive and negative bacteria, it can also be used as antituberculosis drugs.

It is commonly known as amikamycin and amikamycin. The product is a sulfate of a semi-synthetic derivative of kanapenicillin A, white or acacia-like crystalline powder, almost odorless and tasteless. Amikacin is soluble in water and almost insoluble in ethanol.

The specific rotation of the product is taken and weighed accurately, dissolved and diluted into a solution containing 20 mg per 1 ml, and determined according to the lead weighing shed method, and the specific rotation is 97 degrees to 105 degrees. After medication, tinnitus, fullness in the ears, high-frequency hearing loss, and severe cases can progress to deafness.

Clinically, it is mainly used for various infections caused by gram-negative bacilli resistant to gentamicin and kanamycin, such as Escherichia coli, Proteus and Pseudomonas aeruginosa.

This product is suitable for bacteremia, bacterial endocarditis, sepsis (including neonatal sepsis), respiratory tract infection, bone and joint infection, central nervous system infection (including meningitis), **soft tissue infection, biliary tract infection, intraceliac infection (including peritonitis), burns, postoperative infection ( including post-vascular surgical infection) and ** urinary tract infection.

Amikacin should not be used in treatment-naïve cases of uncomplicated urinary tract infections unless the causative organism is not susceptible to other, less toxic antimicrobials.

Amikacin is stable to most aminoglycoside purifying enzymes, so it is suitable for kanamycin, gentamicin, or tobramycin-resistant strains in **Gram-negative bacilli, especially infections caused by Provuedton spp., Serratia marcescens and Pseudomonas aeruginosa.