Mutagenicity of kerosene? Is the oil smoke produced by kerosene heating harmful?

Its mutagenicity refers to its ability to alter the chromosomal base sequence of biological (especially human) cells. Most are nitrosodeamination.

Kerosene, did you try it in your car? You are responsible for the articles you publish.

The pure product is a colorless and transparent liquid, and it is light yellow when it contains impurities. Slightly foul-smelling. Boiling range 180 310 (not absolute, often varies according to the specific situation in production), freezing point:

47℃(-40℃for jet a) 。The average molecular weight is between 200 250. Density.

Melting point -40 or more. The kinematic viscosity is 40. Insoluble in water, soluble in alcohols and other organic solvents.

Volatile. Flammability. After volatilization, it is mixed with air to form the most advanced mixture.

**Limit 2-3%. The combustion is complete, the brightness is sufficient, the flame is stable, no black smoke, no lights, no obvious peculiar smell, and little pollution to the environment.

Kerosene has different chemical compositions for different purposes. The physical and chemical properties of the same kerosene are also different due to different production methods and origins. Various.

The quality of kerosene decreases in order: thermal kerosene, solvent kerosene, kerosene for lamps, fuel kerosene, and washing kerosene.

Kerosene contains 28-48% alkanes, 20-50% or 8% 15% aromatics, 1-6% unsaturated hydrocarbons, and 17-44% cyclic hydrocarbons. The number of carbon atoms is 11-16. In addition, there are small amounts of impurities such as sulfides (mercaptans), gums, etc.

where the sulfur content. Free of benzene, diolefins and cracking fractions.

I don't understand it, the question is too vague.

The main components of oil smoke are: a large number of short-chain aldehydes, ketones and polycyclic aromatic hydrocarbons are produced, these substances are mixed together to constitute oil smoke, the composition of oil smoke components, aldehyde content is the highest, although the content of polycyclic aromatic hydrocarbons is low, but because of its reproductive toxicity, carcinogenicity and mutagenicity, it has become the most dangerous component of oil smoke.

The latter is one of the effects of the former. The specific relationship can only be clarified in a little wordy.

First of all, genotoxicity refers to the ability of a compound to act on the genetic material of a cell, affecting its integrity. For example, radioactive chemicals can act on DNA.

So basically any substance that can act on DNA is genotoxic. Chemicals such as aromatic amines can form strong covalent bonds with DNA through their nucleophilicity, which can impede replication, and in some cases, the absence of a stable covalent bond can prevent the replication of genetic information.

The three major effects of genotoxicity by affecting the genetic information of organisms are carcinogenicity, mutagenicity and teratogenicity. Among them, mutagenicity refers to abnormal protein synthesis caused by abnormal DNA, carcinogenic effect refers to uncontrolled cell proliferation, and teratogenic effect refers to malformation of maternal embryos during pregnancy.

Genetic toxicology tests are also known as genetic endpoint tests. Biological tests that detect changes in mutations and abnormalities in chromosome structure or number, or biological tests that directly measure mutations or chromosomal damage. The U.S. Environmental Protection Agency's Genetic Toxicology Program (1985) proposed the following 10 genetic toxicology tests as routine tests, based on the degree of standardization of the method and the scope of its use (number of compounds tested and number of laboratories used):

Salmonella typhimurium revert mutation test, Escherichia coli revert mutation test, Escherichia coli POLA test, Drosophila companion recessive lethality test, cytogenetic test, sister chromatid swap test, V79 cell HGPRT mutation test, bone marrow cytogenetic test, micronucleus test, dominant lethality test.

The mutagenicity test is the detection test of chemical mutagens, which refers to the primary screening of carcinogens, which is an important means for human cancer prevention, among which the bacterial mutagenicity test is the most widely used.

The difference lies in the purpose, the purpose of mutagenicity experiments is to verify the changes of substances to biological heritability, and genetic toxicology experiments are to verify the damage of substances to biological genetic material and the resulting toxic effects on organisms. To put it simply, mutagenicity experiments study cause and effect, what substances cause which results, and genetic toxicology experiments study processes, and what substances cause those results (genetic mutations in organisms are often toxic to organisms themselves, so the two experiments are often close or identical in terms of experimental process, results, and recorded data).