Is thoracic mesothelioma benign? 80

New developments in pleural mesothelioma**.

Asbestos exposure is the most important cause of malignant pleural mesothelioma. The widespread use of asbestos materials in the 50s and 70s of the last century has increased the incidence of mesothelioma year by year, and it is expected that 2015 to 2030 will be the peak period of mesothelioma incidence in most Western countries.

At present, the efficacy of ** mesothelioma is poor, and most patients have no chance of surgery, and the prognosis is extremely poor. In the past, many phase clinical studies have failed to find specific drugs. Recent randomized trials have looked at the value of pemetrexed and raltitrexed in malignant mesothelioma**.

Preliminary results suggest that pemetrexed combined with cisplatin can prolong survival (median survival is month-to-month) compared with cisplatin alone**, and significantly improve lung function, symptoms and quality of life. Pemetrexed has become the first-line drug for malignant mesothelioma.

The randomized study design of raltitrexed was similar to pemetrexed, and the results were similar. However, it has been suggested that cisplatin as a control is not appropriate because there are no studies that best support the efficacy of ** with chemotherapy. A study comparing the best support**, vinorelbine monotherapy with mitomycin + cisplatin + vindesine plus chemotherapy is ongoing.

Previous studies have suggested that immediate chemotherapy is associated with longer survival and higher symptom control than delayed chemotherapy.

Chemotherapy is associated with a survival benefit in patients with mesothelioma, and preliminary results suggest that chemotherapy followed by surgery or radiation therapy in the early stages of the disease is well tolerated and does not increase surgical complications.

Recently, targeted drugs** mesothelioma have attracted attention, with initial studies focusing on epidermal growth factor receptors and platelet-derived growth factor receptors, but studies of imatinib and gefitinib suggest that they are not effective against mesothelioma. More trials are now turning to the study of vascular endothelial growth factor and its receptors.

Tracheoscopy is still relatively accurate :)

Direct puncture, or surgery and biopsy.

1 Pinyin 2 Clinical manifestations.

3 Basis for diagnosis.

4 ** Principle.

5 Principles of medication.

6 INVESTIGATIONS.

7 Evaluation of efficacy.

xiōng mó jiān pí liú

Pleural mesothelioma is a primary tumor of the pleura, which is a tumor in the four parts of the pleura of the visceral layer, parietal layer, mediastinum or diaphragm. The incidence rate abroad is higher than that in China, and 0 04 respectively. Mortality accounts for less than 1 of all tumors worldwide.

In recent years, there has been a clear upward trend. Over the age of 50, the ratio of men to women is 2:1.

Associated with asbestos exposure. At present, there is a lack of effective methods for malignant type.

1.Localized patients may have no significant discomfort or chest pain and shortness of breath after exertion.

2.Diffuse patients have severe chest pain, shortness of breath, and weight loss.

3.Restricted thoracic movement on the affected side, full and auspicious, dullness to percussion, decreased or absent breath sounds.

4.There may be supraclavicular fossa and underarm lymphadenopathy.

1.Symptoms such as chest pain, shortness of breath, weight loss, etc.

2.Pleural effusion and signs of pleural thickening.

3.Chest x-ray or chest CT shows pleural nodules.

4.Nodules can be seen on thoracoscopy and motile tissue can be forceps to confirm the diagnosis.

Surgery should be preferred in patients with localized form**, and surgery can be combined with chemotherapy in patients with diffuse form.

1.Patients with chest pain should be relieved with cranial tongding, indomethacin, and demerol.

2.Doxorubicin is an effective drug for this disease, and is mostly used in combination with cisplatin, mitomycin, cyclophosphamide, methotrexate, etc.

3.Interferon and interleukin are used as adjunct measures.

4.Patients with pleural effusion can use talcum powder, tetracycline, etc. for pleural adhesions.

Chest x-ray and pleural effusion are the initial screening tests for the disease. Chest CT or MRI if possible; Biopsy with thoracoscopy confirms the diagnosis.

1.**: Symptoms and signs are basically gone, mesothelioma disappears or is surgically removed.

2.Symptoms and signs improved, pleural effusion decreased significantly, and mesothelioma shrank.

Pleural mesothelioma (respiratory medicine) is a primary tumor of the pleura, which is a tumor in the four parts of the pleura in the visceral layer, parietal layer, mediastinum or diaphragm, with an incidence.

Malignant pleural mesothelioma is a high-grade malignant tumor with a poor prognosis, and patients can survive for more than two years if most of the tumor can be surgically removed and combined with radiotherapy and chemotherapy.

Closely related to asbestos contact.

Surgery can be combined with chemotherapy.

Analysis:

Suggestions: It is recommended to have surgery, postoperative with traditional Chinese medicine, prevention, and the dynamics of traditional Chinese medicine is the best method at present, which can effectively reduce or eliminate tumors, improve immunity, and achieve the purpose of treating both symptoms and root causes.

Hello My mother is also a malignant pleural mesothelioma, can you please talk about 281612364

Analysis:

Suggestions: Pleural mesothelioma can originate from the visceral layer, parietal layer, mediastinum and diaphragmatic pleura, and is a rare tumor. Generally, there are two types: localized mesothelioma is mostly benign and diffuse mesothelioma is mostly malignant.

Judging from your patient's CT report, there is a high probability of malignancy.

The cause and mechanism of the disease are still not very clear, and may be related to the following factors: 1Long-term exposure to asbestos is considered to be the main cause of the tumorAll kinds of asbestos fibers, almost all of which are related to the pathogenesis of mesothelioma, but the risk of each fiber is not the same, the most dangerous is exposure to crocidotile asbestos, and the least risk is exposure to yellow asbestos.

The incubation period from the first exposure to asbestos to the onset of the disease.

Doctor: Liu Feng's condition analysis: If you have chest pain, it is recommended to first check whether there is a lung infection, pleurisy, tuberculosis, pneumothorax, and whether there is a possibility of intercostal neuritis and costochondritis.

Sometimes it is also important to note that peptic ulcers and pancreatic diseases can also cause this phenomenon. Suggestions: Also pay attention to check whether there is a problem with liver and gallbladder ultrasound and liver function.

Also do an electrocardiogram is.

The cause and mechanism of the disease are still not well understood, but may be related to the following factors:

1.Long-term exposure to asbestos.

All kinds of asbestos fibers are almost all related to the pathogenesis of mesothelioma, but the danger of each fiber is not the same, the most dangerous is exposure to crocidotile asbestos, and the least dangerous is exposure to xanthemia. The incubation period from the first exposure to asbestos to onset is generally 20 to 40 years, and the incidence of mesothelioma is proportional to the time and severity of exposure to asbestos. Evidence of asbestos-induced pleural mesothelioma:

1) Animal experiment: Asbestos liquid can induce pleural mesothelioma;

2) asbestos fibers found in malignant mesothelioma;

3) Asbestos workers, especially those who have worked for 20 to 40 years, have found that the incidence of mesothelioma is as high as high at autopsy.

2.Other non-asbestos causes.

Exposure to natural mineral fibers, chronic collapse of the pleural space (tuberculous pleurisy), and recurrent lung infections. Cases of pleural mesothelioma after exposure to radiation have also been reported, and the time from exposure to radiation to detection of pleural mesothelioma is 7 36 years, with an average of 16 years.

3.Simian disease 40sv40 (infected).

In patients without a history of asbestos exposure, 30% to 50% may be associated with SV40 infection. During the polio epidemic, millions of Americans could have contracted SV40 as a result of the SALK vaccine. Recently, he and his colleagues isolated SV40 fragments in 60% of patients with mesothelioma and successfully induced mesothelioma after injecting SV40 into the intrathoracic mold of rats.