How much glimepiride tablets need to be taken and how to take them

Glimepiride tablets are oral drugs, as for the dosage of the drug, it also depends on the severity of the disease, the age of the patient's friends, the sensitivity to the drug, etc. After all, the doctor is a professional, and when it comes to the dosage of drugs, especially for children, it should be left to the doctor to decide.

Please strictly follow the instructions and the doctor's prescription, and it is recommended that you consult professionals in the relevant field in detail and follow the doctor's instructions! Due to seasonal, regional and other reasons, glimepiride tablets** may fluctuate to a certain extent, but the fluctuation is not large. Glimepiride tablets should therefore actually be takenCardinal Health's PharmacyThe actual selling price of each store shall prevail.

DosageIn principle, the dose of glimepiride tablets should be adjusted according to the target blood glucose level. The dose of glimepiride tablets must be the lowest dose sufficient to achieve target metabolic control. During the application of glimepiride tablets**, blood glucose and urine glucose levels must be measured regularly.

In addition, regular measurement of glycosylated hemoglobin is recommended. If an error such as a missed dose occurs, it should not be corrected by taking a higher dose of the drug later. Measures to deal with the inability to take medication at the prescribed time (especially if you forget to take your medication or skip a meal) or if you are unable to take your medication on time for various reasons must be discussed and agreed upon by both the doctor and the patient.

The starting dose and dose adjustment are starting with 1 mg of glimepiride tablets per day. If necessary, the daily dose can be increased. It is recommended to monitor blood glucose regularly and adjust the dose, and the recommended dose should be gradually increased, such as 2 mg, 3 mg, 4 mg, and 6 mg per day every 1-2 weeks.

Dosage range for patients with well-controlled diabetes mellitus, the usual daily dose is 1 mg to 4 mg glimepiride tablets. Doses greater than 6 mg per day are more effective only in a small number of patients. The dosing distribution is up to the doctor to decide the timing and distribution of the dosing based on the patient's current lifestyle.

It is generally recommended to take it once a day immediately before breakfast, and if you skip breakfast, take it immediately before the first meal. It is very important not to skip meals after taking the medication. Due to improved diabetes control and increased insulin sensitivity, the need for metallemetin may decrease.

Therefore, to avoid hypoglycemia, it is important to consider reducing the dose or discontinuing glimepiride tablets in a timely manner. Dose adjustment should also be considered if the patient has a change in weight, lifestyle, or other factors that increase sensitivity to hypoglycemia or hyperglycemia. **Duration: Normal use of glimepiride tablets is a long-term**.

Switching from other oral hypoglycemic drugs to glimepiride tablets There is no clear dose relationship between glimepiride tablets and other oral diabetes** drugs. When replacing other oral hypoglycemic drugs with glimepiride tablets, it is recommended to use the same method as the initial dose starting with 1 mg per day. This also applies to patients who have previously taken the maximum dose of another oral diabetes** medication.

The efficacy and duration of action of previous diabetes medications must be considered. Temporary discontinuation of medication may be required to avoid the risk of hypoglycemia due to the additive effects of the medication. Switching from insulin to glimepiride tablets Except in a few cases, patients with type 2 diabetes who are on insulin** may be switched to glimepiride tablets**.

Replacement of insulin with glimepiride tablets should be done under close supervision by a doctor. The use of faglimepiride tablets should be swallowed with a sufficient amount of liquid (about 1 2 cups) and should not be chewed. Renal insufficiency in special populationsThere is limited information about the use of glimepiride tablets in patients with renal insufficiency.

Patients with impaired renal function may be more sensitive to the glucose-lowering effects of glimepiride tablets (see [Pharmacokinetics]).

Glimepiride tablets are indicated for non-insulin-dependent diabetes where blood sugar control is not satisfactory for food, exercise** and weight loss. When taking glimepiride tablets, it should be taken immediately before or during a meal. Irregular or absent meals with glimepiride tablets** can cause hypoglycemia.

Possible symptoms of hypoglycemia include headache, extreme hunger, nausea, vomiting, weakness, and drowsiness. Sleep disturbances, irritability, aggressive behavior, inattention, slowed reactions, depression, confusion, visual impairment, incoherent speech, aphasia, tremor, paresis, sensory disturbances, dizziness, feelings of helplessness, loss of self-control, delirium, cerebral convulsions, drowsiness and loss of consciousness, and even coma, shallow breathing and bradycardia.

In addition, signs of adrenergic reverse regulation, such as diaphoresis, clammy cold, anxiety, tachycardia, hypertension, palpitations, angina, and arrhythmias, may also be present. Symptoms of a severe hypoglycemic episode can be similar to that of a stroke.

Immediately after taking carbohydrates (sugars) orally, the symptoms of hypoglycemia described above almost completely disappear. Artificial sweeteners are ineffective in hypoglycemia. It has been learned from other sulfonylureas that hypoglycemia may persist despite initial successful control of hypoglycemia**.

In patients with severe or long-term hypoglycemia, regular amounts of sugar can only temporarily control symptoms, requiring urgency** and, in some cases, hospitalization**.

In the initial ** phase, the starting dose of glimepiride is 1 2 mg once a day, administered at breakfast or at the second main meal. For diabetic patients, there is no fixed dose of glimepiride or any other glucose-lowering drug, and fasting glucose and glycosylated hemoglobin must be measured periodically to determine the small effective dose of the patient's medication; Glycosylated hemoglobin levels are measured to monitor the patient's ** effect.

The initial dose is 1 mg once a day, preferably with breakfast, and is increased by 1, 2, 3, 4, and 6 mg every 1 to 2 weeks according to the results of blood glucose monitoring, with a maximum dose of 8 mg for individual patients.

Dosage should generally be based on blood glucose levels, and the smallest dose should be used to achieve satisfactory glycemic control. The initial dose and maintenance dose are determined based on the results of regular blood glucose and urine glucose monitoring, and monitoring blood glucose and urine glucose can also help determine whether the drug has primary or secondary failure.

Initial dose and dose adjustment: The initial dose is 1 mg once a day. The daily dose can be increased if needed.

It is recommended to increase the dose gradually according to the results of blood glucose monitoring, such as 1 mg 2 mg 3 mg 4 mg 6 mg every 1 2 weeks, up to 8 mg in individual patients.

Patients with well-controlled diabetes mellitus generally have a dose of 1 4 mg per day, and only a few patients have a dose greater than 6 mg per day.

Duration of medication: The duration of the medication is determined according to the patient's lifestyle. Generally, it can be taken once a day, and it is recommended to take it before breakfast, or before the first main meal if you skip breakfast. In particular, don't forget to eat after taking the medicine.

Follow-up dose adjustment: With the improvement of diabetes symptoms and the increase of insulin sensitivity, the need for this drug should also be gradually reduced, and the dose should be reduced or even stopped in time to avoid hypoglycemia. The ** of this drug generally needs to be carried out for a long time.

Change from other oral hypoglycemic drugs to this drug: This drug has no exact dose relationship with other oral hypoglycemic drugs. When using this drug instead of other oral hypoglycemic drugs, the recommended starting dose is 1 mg per day, even when the maximum dose of other oral hypoglycemic drugs is being used.

The dose increase of this drug should be done in accordance with the requirements of the above "initial dose and dose adjustment method". Considering the efficacy and duration of previous hypoglycemic drugs, it is necessary to interrupt** to avoid hypoglycemia caused by the cumulative effect of drugs.

oral, start tablets), once before breakfast or once before breakfast and lunch, half a tablet for mild patients), three times a day, before three meals, and increase daily tablets after 7 days). The general dosage is 5 10 mg per day (2 4 tablets per day), and the maximum dosage does not exceed 15 mg (6 tablets) per day.