Why does a cold make myasthenia gravis worse?

Hello, colds are like this, generally just cold time clear, may stay between two or three days, his cold will be more serious, after three or four days will be fine, drink more water and rest.

The antibodies in patients with myasthenia gravis cannot be stimulated, and if they are provoked, they will be aggravated. When you catch a cold, the antibodies in the body will come out to fight the virus

Because of colds, immunity is weakened.

You can try Chinese medicine**.

It's best to hold on to a cold**.

Overwork, nervousness. If the patient sits in front of the computer for a long time to play games, or plays mahjong for a long time, it will lead to myasthenia gravis, so we must ensure the combination of work and rest, and maintain a happy mood, which can prevent the disease well.

Genetic factors. Myasthenia gravis is also a disease that has a lot to do with genetic factors, so if you have a history of this disease in your family, you must be vigilant and go to the hospital regularly for check-ups to see if you have myasthenia gravis.

Viral infections. Myasthenia gravis is also very related to thymic lentivirus infection and low immune function, so everyone should strictly prevent the occurrence of colds and often do physical exercise to enhance their own resistance.

Food poisoning and contamination. There are many patients who are infected with myasthenia gravis after eating unclean fried fritters or drinking low-quality drinks contaminated with chemicals, which is one of the most common causes of myasthenia gravis.

Nutritional factors. Most patients with myasthenia gravis have difficult family conditions, which may be related to long-term nutritional deficiencies or long-term fatigue, which may also lead to myasthenia gravis.

Autoimmune abnormalities. Clinical studies have found that many immune indicators in patients with this disease are abnormal, and the clinical symptoms disappear after menstruation, but the abnormal immune indicators do not change, which may be an important factor in the instability and ease of the disease.

Hello, according to your description, you are talking about this condition, myasthenia gravis, is an autoimmune disease caused by a dysfunction of transmission at the neuromuscular junction. Myasthenia gravis is unknown, and may be related to autoimmune diseases, infection, drug environmental factors, etc. In your case, it is recommended that you actively go to the hospital and let the doctor check you out, and after the diagnosis, the symptoms will be corrected**.

Common myasthenia gravis is a chronic disease, whether it is during the onset of the disease or ** myasthenia gravis takes a long time, the harm of myasthenia gravis disease is very serious, endangering the physical and mental health of patients, so, what is the serious impact of myasthenia gravis?

1. Induce changes at the neuromuscular junction:

Morphological changes in the neuromuscular junction are the most characteristic changes in the pathology of myasthenia gravis, often in the disappearance and flattening of the postsynaptic membrane folds, or even rupture.

2. Let the changes in muscle fibers:

In the early stage of the course of the disease, there is lymphocyte infiltration around the small blood vessels, with small lymphocytes as the main one, and this phenomenon is called lymphatic leakage; In acute severe disease, coagulative necrosis of muscle fibers, and exudation of macrophages with polymorphonuclear leukocytes is one of the hazards of myasthenia gravis.

3. Causes changes in the thymus:

Myasthenia gravis is less common in patients with thymoma, and more than half of patients have thymus hypertrophy, usually with thymic tissue hyperplasia. Adenomas are divided into lymphatic fine thoracic type, epithelial cell type, mixed cell type, and the latter two are often accompanied by myasthenia gravis.

I can't work, I can't walk, and in severe cases, I can be paralyzed.

1. In recent years, according to ultrastructural studies, myasthenia gravis is mainly caused by the lesion of acetylcholine receptor (ACHR) in the postsynaptic membrane.

2. Many clinical phenomena also suggest that the disease is related to the disorder of immune mechanism.

3. Myasthenia gravis is an autoimmune disease that affects the transmission of neuromuscular junctions, and its exact pathogenesis is still unclear, but there are still many studies on the disease, among which, the most studied is the relationship between myasthenia gravis and thymus, and the role of acetylcholine receptor antibodies in myasthenia gravis, and a large number of studies have found that the number of acetylcholine receptors (ACHR) on the postsynaptic membrane at the neuromuscular junction in patients with myasthenia gravis is reduced, and there are anti-ACHR antibodies at the receptor site. and the deposition of IgG and C3 complexes on the postsynaptic membrane.

It has also been shown that the increase in anti-ACHR antibodies in the serum and the decrease in the number of effective ACHR caused by the deposition on the postsynaptic membrane are the main causes of the disease. The thymus gland is the main site of ACHR antibody production, so the occurrence of this disease is generally closely related to the thymus. Therefore, regulating the number of ACHR in the human body, increasing its number, resolving the deposition on the postsynaptic membrane, and inhibiting the production of anti-ACHR antibodies are the key to this disease.

Pathological diagnosis of myasthenia gravis.

The pathological morphology of myasthenia gravis includes three parts: muscle fibers, neuromuscular junctions, and thymus.

1. Changes in muscle fibers: In the early stage of the disease, there are mainly lymphocyte infiltrates between muscle fibers and around small blood vessels, mainly small lymphocytes, which is called lymphatic leakage; In acute severe disease, there is coagulative necrosis of muscle fibers, accompanied by macrophage exudation of polymorphonuclear leukocytes; In advanced stages, muscle fibers may have varying degrees of optic nerve changes, and the muscle fibers are small.

2. Changes at the neuromuscular junction: The morphological changes at the neuromuscular junction are the most characteristic changes in the pathology of myasthenia gravis, which are mainly manifested in: the postsynaptic membrane fold disappears, flattens, and even breaks.

3. Changes in the thymus: about 30 patients with myasthenia gravis have thymoma, 40 to 60 patients have thymus hypertrophy, and more than 75 patients have central hyperplasia of thymus. Adenomas are classified according to their cell type:

Lymphocytic, epithelial, mixed-cell, the latter two are often associated with myasthenia gravis.

The causes of myasthenia gravis are divided into two categories: one is congenital hereditary, which is very rare and has nothing to do with autoimmunity; The second group is autoimmune diseases, which are the most common.

General weakness: Symptoms of myasthenia gravis include those who appear to be well-skinned and fleshy, and who do not appear to have muscle atrophy and do not appear to be sick; However, patients often feel severe general weakness, unable to lift shoulders, unable to lift hands, unable to stand up after squatting, and relying on others for help even for their face and hair. Myasthenia gravis at rest patients have significantly improved symptoms, and doing a little work will greatly increase and seems to resolve.

Double vision: i.e., double vision. Seeing together with two eyes, one thing becomes two; If a patient with myasthenia gravis covers one eye and then sees a very young child who does not always describe diplopia, compensating for head tilting, torticollis, so that diplopia disappears and can be seen clearly, and in severe cases it can also manifest as strabismus.

Symptoms of myasthenia gravis include the appearance of good skin and flesh, and no muscle atrophy.

Severe disease, resulting in weak muscle contraction, that is, the gradual loss of strength of the muscles attached to the bones and able to make movements. At first, patients tend to fatigue and feel more tired after activity, which is relieved by rest, which can manifest as eyelid ptosis weakness (MG), an autoimmune disease caused by dysfunction of transmission at the neuromuscular junction, dysphagia, speech weakness, and even breathlessness. Ptosis is the first to appear.

The causes of the disease are divided into two categories, one is congenital hereditary, which is very rare and has nothing to do with autoimmunity; The second group is autoimmune diseases, which are the most common. The cause of the disease is unknown.

Patients with myasthenia gravis often feel soreness and discomfort in their eyes or limbs at the beginning of the disease, or blurred vision, and are easily tired."

Myasthenia gravis hazards:

1) Dropy eyelids, blurred vision, diplopia, strabismus, and inflexible eye movement.

2) Indifferent expression, wry smile, large tongue, difficulty in arthria, often accompanied by nasal voice.

3) Weakness in chewing, choking on drinking water, and difficulty swallowing.

4) Weak neck, difficulty in raising the head, weakness in turning the neck and shrugging the shoulders.

5) Difficulty in raising arms, combing hair, going up stairs, squatting, and getting on the bus.

6) Ptosis is the first to appear, and it is unlikely that the condition will worsen and be life-threatening.

Myasthenia gravis is very serious, and many patients die of this disease every year, so the best way for this disease is to prevent it in life.

Once a person suffers from a disease, it will seriously endanger their own health, and it will also affect normal work and life, especially for the disease myasthenia gravis, the patient may appear to be thin and thin, and the mood will also be seriously hit, for the patient should know about the relevant knowledge of this disease, so why do you get myasthenia gravis?

1. Overwork and mental stress

There are many causes of myasthenia gravis, among which overwork and mental stress are one of the main reasons for the onset of this type of disease, there are many factors that cause mental tension in general life, if you can't pay attention to it, it will cause myasthenia gravis, so you must maintain a combination of work and rest in your daily life, and at the same time maintain a happy mood, and do a good job of prevention in ordinary times.

2. Genetic factors:

Myasthenia gravis has a lot to do with genetics, if someone in the family suffers from this kind of disease, they should pay enough attention to it, and regularly go to the hospital for relevant examinations, if the diagnosis is made, it should be carried out as soon as possible, and get rid of the disease as soon as possible.

3. Viral infection:

Myasthenia gravis is also closely related to infectious viruses and low immunity, so it is important to prevent colds and actively engage in physical exercise to enhance your body's resistance.

4. Food poisoning and contamination:

If you often eat some fried and fishy foods, it will also cause diseases. This can cause serious intestinal effects, and if you are regularly exposed to chemical contaminants, it can lead to increased myasthenia gravis.

The above is the main myasthenia gravis, people should understand, do a good job of prevention in life, stay away from those who cause myasthenia, and should also pay attention to maintaining a positive attitude in those suffering from myasthenia gravis, go to those specialized hospitals for myasthenia, cooperate with the doctor's advice and requirements, and strive to get rid of the disease as soon as possible.

Myasthenia gravis is an autoimmune disease that, like other autoimmune diseases, is caused by a disorder of the body's immune system that disrupts the body's normal "order". Myasthenia gravis is the attack of acetylcholine receptors in the postsynaptic membrane of the neuromuscular junction by autoantibodies, and when the function of this important receptor is abnormal, it will directly affect the normal conduction and action of neuromuscles.

Disorders of the body's immune system are generally related to environmental factors, infection factors, drug factors, etc., but the specific causes of myasthenia gravis are not clear. Patients with myasthenia gravis often have other autoimmune diseases such as hyperthyroidism, thyroiditis, systemic lupus erythematosus, rheumatoid arthritis, and pemphigus.