What kind of medicine is parkecillin and what exactly is a parkaxillin

Perhexiline

Dicyclohexylpiperidine, Pericarda, Xinshuning, Pexid).

Properties] Commonly used its maleate, white crystalline powder, odorless, tasteless, melting point 192 195. Insoluble in water, ethanol, acetone, slightly soluble in benzene, soluble in chloroform.

Pharmacology and application] is a calcium antagonist, which has the effect of inhibiting Ca2+ influx, dilating vascular smooth muscle, significantly dilating coronary arteries, increasing coronary blood flow, and has a good effect on angina. However, due to its high number of drugs (peripheral neuritis, increased intracranial pressure, liver dysfunction), it is limited as the preferred antianginal agent. At the same time, this product can slow down the heart rate and reduce the load on the left ventricle, thereby reducing myocardial oxygen consumption.

It has a good effect on clinical use for angina. It is also effective for ventricular arrhythmias, but has poor efficacy for supraventricular arrhythmias; For patients who are ineffective with other antiarrhythmic drugs, this product can often be effective.

Uses: 100 mg once a day, 2 times a day, then gradually increase to 300 400 mg a day, the maximum amount is 600 mg a day.

Note] Common *** are dizziness, headache, nausea, vomiting, loss of appetite, etc. A few have weakness, gait instability, confusion, drowsiness or insomnia, liver dysfunction, peripheral neuritis, and increased intracranial pressure.

Preparations] tablets (capsules) dosage: 50mg per tablet (capsule).

This year? Well,,, is there one? Does it matter? It probably doesn't matter.

One is a noble nib, two is a brand, three is a design, and four is not a necessity. A good fountain pen already belongs to the category of luxury, and Parker's best century series counter is more than 6,000, and it is only 2,400 to find **. It's not that expensive.

Parker in the same kind of world famous pen, ** is moderate, fountain pen is now a niche commodity, high added value, single profit is relatively large, especially the famous pen, it is normal to feel a little expensive.

That's because many parts of Parker's fountain pens are 18k**.

**Shop "Jingdong High Quality"**It's quite cheap,**Pike,Picasso heroes have,

Bifurcate. The nature of the gold tip is very soft, and pressing hard will cause it to deform. In everyday use, it's normal for writing to split slightly, and it's not a disadvantage.

Drow is a basic style, not a high-end style. If you give it away, it doesn't have to be Chief and Century, but I personally think that Chief is not easy to use, because it is too heavy and has a very slippery feel. If you are really willing to spend money, a century is definitely the best choice.

Personally recommend the Elite series. This series is moderately priced, around 2000-3000, but the shape is novel and the writing is very smooth. By the way, XF tips are not recommended.

The F tip is smoother, and the XF hanging paper. (If you want to buy the Chief series, it's better to go black, not the bells and whistles.) ）

Writing homework Pike really doesn't fit very well, it's on the rough side.

If you really want to say it, the cheaper one is Wycombe Abbey, and the ****** of the glue rod is more than 50 yuan and then a little higher-grade, IM or urban, about 300, which is very easy to write, but it feels a little heavier, and the homework is tired.

Further up, it's Zhuoer, and the students use it for a little luxury......If you write homework, we recommend two brands: Baile and Lamy, the former is Japanese, the tip is relatively thin, suitable for writing Chinese, ***, the latter German goods, good feel and good design, the most famous series safari** is more affordable.

Don't count it, I feel that Zhuoer is an entry-level level, if you buy Zhuoer, you can't get into it.

Parker Drow steel rod with a black brushed finish.

Parker fountain pen nib has excellent elasticity, a little hard press, the nib will be forked, this is normal, the fork is restored as soon as you let go, completely within the elastic deformation. In this way, you can write words with obvious changes in the thickness of the strokes. This should be an advantage.

JD.com's self-operated Parker pen can generally be guaranteed**, but the third-party merchant sales cannot be determined.

George Parkerpen, the founder, was born in 1863 in Scholsburg, Wisconsin, USA. From 1880 George. Pike works at the Valentine School.

To compensate for his pitiful salary, George. Pike became a middleman, mainly helping John. Holland's pen company sells pens to his students.

Like many fountain pens of the time, these pens always had technical problems, including ink leakage and ink supply failures. After receiving many complaints from his classmates, George. Parker began volunteering to revise pens for his students.

He took each pen apart and repaired it before returning it to the student. George. Parker designed and manufactured his own fountain pen, the Parker Pen, with his experience in mechanics.

That's where the Parker pen comes in.

This**If you buy a fake, the character is too low, and the pen should be analyzed from**, but !! If you buy this pen for about 400, you can get it**.

To judge the authenticity, you can go to the Parker counter for comparison, or contact the Parker company to mail the counterfeit inspection, and you can check the nib, cover and tongue of the pen yourself.

It's true, I think he can provide anti-counterfeiting barcodes, which can be directly verified by the official.

1. The elasticity of the pen clip.

Authentic Parker pen nibs have a certain curvature, elasticity and bending space, so you can try it with a gentle break.

2. The flatness of the thread at the interface.

Counterfeit products in the market do not pay much attention to the thread of the interface, so the thread of counterfeit products is very messy, and there is a very smooth and orderly thread.

3. The number of feather strokes of the pen clip.

The Parker pen clip is in the shape of a feather arrow, and the 03 model of Zhuoer is 7 strokes on the left and right, the 08 model is 5 strokes on the left and right, and the urban IM is 7 strokes on the left and right.

4. Send it directly to Parker for verification.

Parker pen products can be sent to Parker company for direct identification, the genuine goods will be returned, and inform whether it is genuine, fake goods will be directly confiscated and show the inspection report, Parker's company address is in Shanghai, and the instructions and warranty cards in the gift box have an address.

Hello, I am lucky to be able to answer your questions, each of the Parker pens is different, Parker pens are currently divided into the following series, century, chief, elite, Zall, urban, im, which** compared im, the city in 100-800 range, Zall is divided into gold pens and pens, gold pens **thousands, and chief, century belongs to the high-end series, **also from thousands to tens of thousands (commemorative pens), if it is for viewing alone, and sufficient funds, it is recommended to choose a commemorative pen, and if it is for writing, I think it is more appropriate to be drow, elite, century.

Look at the specific model, style and channel. The cheap one hundred and ten yuan, the expensive one hundred thousand.

Let's say, I'm still familiar with Parker, first of all, let me tell you, ** on more than 100 on a lot of real pens, this is undoubted, excellence is also real pen, ** there are true and false, excellence must be true, just a little more expensive, the price of your department store is too crazy, actually higher than the official guide price, I think, the public price should be Liya 600, frosted 500

Parker fountain pens are real and fake, and insiders can see it, but laymen can't. At the very least, one or two thousand.

However, there is a fountain pen that is very unique, and it is not expensive to sell here in Hebei (calligraphy pen).