Tuberous sclerosis complex How is it treated? Urgent !! Kneel and beg for !!

I've seen a case before that was accompanied by psychiatric symptoms.

This is an incurable disease.

At the moment it can only be symptomatic ** ** very difficult.

As for the kidneys, you don't provide information about kidney function, so it's hard to give an opinion.

Personally, I think there is an option for intervention** or surgery**.

However, it is prone to kidney failure and lesions**, and ordinary doctors do not dare to deal with it rashly.

Tuberous sclerosis** methods are as follows:

1. Selection method according to the involved site: in the case of epilepsy, anti-epileptic drugs are the mainstay, infantile spasms, and the first choice is amohexenic acid;

2. Choose drugs according to the type of seizure: carbamazepine can be selected for partial seizures;

3. For **Conduct**: Everolimus and sirolimus are M-TOR inhibitors, which can inhibit tumor growth in vivo, including intracranial SEGA, renal renal vessels;

4. **Change: If the face is more serious, M-Tor inhibitors can be used, and if the drug effect is not obvious, local laser can be performed**. The specific medication should be combined with clinical practice, and the doctor's face-to-face guidance shall prevail.

Tuberous sclerosis, there is no specific method, mainly symptomatic. Including seizure control, cranial pressure reduction, etc., patients with infantile spasms can be given ACTH, patients with obstruction of cerebrospinal fluid circulation can undergo surgery**, and facial sebaceous adenoma can be given facelift**. Tuberous sclerosis complex is a genetic disorder of the nervous system.

Its clinical features are facial vascular nevi, seizures and mental retardation, which is autosomal dominant and sporadic cases are common. The main pathological changes are glial proliferative sclerosis nodules, which occur widely in the cerebral cortex, white matter, basal ganglia, and submembrane of the esophagus. It is often accompanied by calcium deposition and may be characterized by ectopia and vascular hyperplasia.

For tuberous sclerosis, it is necessary to understand the condition first, and for mild cases, it can be controlled with drugs, such as the commonly used target of rapamycin. If you have tuberous sclerosis complex seizures, you also need to use some anti-epileptic drugs to control them, but if the drugs are not well controlled and there are symptoms of increased estrogen, surgery is needed as soon as possible**.

At present, there is no effective treatment for tuberous sclerosis, and the means can only be symptomatic to support and alleviate the progression of the disease. After tuberous sclerosis, it is necessary to go to a regular hospital for further medication in a timely manner, pay attention to nursing, the disease itself is a genetic factor caused by ** and nervous system and other diseases involved, with strip hypopigmented spots, facial angiofibromas, epilepsy, intellectual disability as the main manifestations.

Adrenocorticotropic hormone** can be used for infantile spasms, intracranial pressure can be reduced with dehydrating agents, cerebrospinal fluid circulation can be surged**, and facial angiofibromas can be cosmetic. Symptomatic** improves quality of life.

Tuberous sclerosis is a relatively common disease in our lives, and many people in our lives will find that there are various nodules in our lives. There are more and more people suffering from tuberous sclerosis in our lives, and we must strengthen prevention in our lives. At the same time, when tuberous sclerosis is discovered, it is important to go to the hospital as soon as possible**.

Generally speaking, the best time for tuberous sclerosis is at the beginning of the disease. Of course, if the patient suffers from cerebral nodules, then epilepsy must be considered. Cerebral nodular sclerosis is first taken with anti-epileptic **, so that the patient can avoid trauma at the onset of the disease.

Because tuberous sclerosis is a chromosomally dominant disease, it usually causes lesions in the brain,** and kidneys. Therefore, the first time we have tuberous sclerosis should be epilepsy. If the patient has intellectual disability and behavioral disorder, the patient's quality of life must be ensured as much as possible, and other ** can be taken on the premise of ensuring the patient's quality of life.

In any case, tuberous sclerosis is best done at an early stage, so that the patient does not suffer a lot. Because the early stage is the best period for tuberous sclerosis, we must remember this to the patient's friends and family members, the sooner the better. At present, there are many ways of tuberous sclerosis, and surgery is mainly for nodular disease.

The best stage of tuberous sclerosis is the early stage, and we must grasp this best period of disease, so that we can achieve twice the result with half the effort.

Tuberous sclerosis complex is an autosomal dominant neuro** syndrome, most of which are caused by abnormalities in the organs of ectoderm fluid tissue, including multiple organs such as the brain, **, peripheral nerves, and kidneys.

The main clinical features are sebaceous adenoma of the face, seizures, and mental retardation. The cause of the disease is mainly due to genetic inheritance, familial cases account for about one-third of cases, depending on the affected area, patients can have different clinical manifestations, generally more local than childhood, more men than women.

Patients may present with the following manifestations: ** lesions, especially sebaceous adenoma in the triangular region of the mouth and nose, symmetrical butterfly-shaped distribution, pale red or reddish-brown, pinpoint to the size of broad bean, hard, waxy papules, pressed until slightly faded.

Neurological damage, epilepsy is the main neurological symptom, accounting for 70% to 90% of the cases. Seizures begin in infancy and early childhood, and patients are often accompanied by mental symptoms such as mental decline, emotional instability, naïve behavior, impulsivity, and disordered thinking, and a few patients also have positive signs of the nervous system.

Abnormalities may be seen in the brain, eyes, kidneys, bones, heart, and lungs. The brain typically presents with cortical nodules, subependymal nodules, and myelin lesions. Cortical nodules are hard, grayish-colored nodules with a raised gyrus of about 1-2 cm in diameter, ranging in number, and microscopic nodules are glia composed of some large multinucleated monomorphic cells.

Nodules thin the normal cerebral cortex. Most commonly found in the frontal lobe, but rarely in the brainstem, cerebellum, or spinal cord, subependymal nodules are often in the anterior corner of the lateral ventricles, microscopically a number of overproliferated large astrocytes, and the nodules tend to calcify in varying numbers.

Tuberous sclerosis complex can also sometimes see partial absence of the cerebral cortex, which may be related to the blockage of neuronal migration during neocortical formation, and insular gray matter ectopic or demyelination zones are often seen deep in the absent area. In some children with mental retardation, more areas of anticutaneous defects or multiple nodules may be seen.

Nodules can also occur in other organs, and in the heart appear as rhabdomyomas, which occur in children with tuberous sclerosis complex, and about 1 in 4 children with rhabdomyomas die of heart failure within a few days of life.

There are about 50 to 80 cases of multiple renal swelling and pain, often.

Tuberous sclerosis complex is a common chromosomal dominant disorder. Penetrance is variable, with a positive family history accounting for 20% to 30% of patientsThe typical appearance of the brain is subependymal nodules, often in the anterior angle of the lateral ventricles, and proliferative astrocytes can be seen under the microscope, and the nodules have a tendency to calcify in varying numbers.

The cortex also has hardened nodules that can cause different neurological symptoms. There can also be different changes, the essential characteristics of retinal hamartoma, can also cause changes in vision, cause seizures, intellectual development, can accumulate other parts except skeletal muscle, according to the type of different types of seizures, use different methods, different epilepsy drugs. For seizure types based on local styling, carbamazepine can be used.

Valproic acid is mainly used for generalized seizures, ACTH is mainly used for spasmodic seizures in infants, because the brain lesions are multiple, the surgical effect is not good, if the tumor is located in an important site causing spasmodic seizures, callose body dissection** can be performed. Because it is a hereditary disease, there is no satisfactory ** plan, but some methods and means can be used to improve some symptoms. If the effect of the drug is not good, local EEG seizure, extracerebral surgery can be considered, and good results can be obtained.

Common regimens include drugs and surgery. Drugs** Sirolimus is generally used, antiepileptic drugs. Surgery** is generally used when the condition is more severe. Choose the best plan for yourself according to your own condition.

**Principle: Specificity**, Synthesis**.

Specificity**.

Specific targeting** method: The use of specific inhibitors can be effective** subependymal giant cell astrocytoma, cardiac rhabdomyomas, etc.

Synthesis**. Cardiac rhabdomyomas: Surgery should be done if the tumor is large**.

Antiepileptic**: Vigabatrin is the antiepileptic agent of choice for TSC in addition to specific inhibitors, and adrenocorticotropic hormone may also be used.

Cosmetic Surgery**: For patients with facial sebaceous adenoma.

Surgery**: Mainly for subependymal giant cell astrocytoma and renal angiomyolipoma.

This disease is characterized by facial sebaceous adenoma, seizures and mental retardation. In addition, abnormalities may occur in the brain, heart, eyes, lungs, kidneys, **, etc., which are autosomal dominant inheritance. Tuberous sclerosis is mainly based on epilepsy control, supplemented by some traditional Chinese medicine.

It is important to control the symptoms in a timely manner, which can be controlled by medication or surgery. You can consult a doctor.

Latest (4 entries).

Anonymous usersIt is difficult to cure, and symptomatic treatment can improve the quality of life of patients.

Measure. Maintain a calm mind and actively cooperate**; Proper shipping.

Exercise, intensify exercise; Follow the doctor's advice, use drugs rationally, and return regularly.

Examine. <>

Anonymous usersDietary advice.

Ketogenic diet. **Principle.

Rapamycin** or surgery** may be used.

**Sexual inability**, can rely on drugs to relieve symptoms.

Important Reminder. If one of the parents is a TSC patient, there is a 50% chance that the child will inherit the TSC, so genetic counseling or genetic testing and prenatal diagnosis will be performed before pregnancy.

Flying pigs. Tuberous sclerosis, a hereditary disease, is caused by a number of chromosomal or genetic disorders. Therefore, it is very difficult for this disease to achieve complete **, and there is a lack of some very effective ** means. Tuberous sclerosis complex mainly manifests some ** nodules, some seizures, and some cognitive dysfunction.

Anonymous usersTuberous sclerosis complex, a dermatologic syndrome with dominant chromosomal inheritance. Generally, it is inherited by one of the parents. Currently, remission with surgery or medication is recommended.

If the condition is not very severe, medication** is usually administered and, if necessary, surgery.

Tuberous sclerosis has many manifestations, one of which is damage to the human nervous system, resulting in seizures. If this is the case, it can be combined with some seizure suppression medications**. However, most of the patients are children, and they should not only pursue the best effect, but should take the drug according to the characteristics of the child's own development.

Take it on time according to the doctor's instructions, and do not increase or decrease the medication according to the development of the disease. If the drug has little effect at an advanced stage, surgery** should be taken as soon as possible, such as surgery such as local cerebral cortextomy.

Another manifestation of tuberous sclerosis is the destruction of the patient's **, sebaceous adenoma will grow in the triangular area of the mouth and nose, affecting the appearance of the person, if you want to restore the appearance, you can take medical aesthetic measures to reduce the impact of sebaceous adenoma as much as possible. In addition, in daily life, we should pay attention to personal hygiene, change clothes frequently, and keep them dry and clean. Actively engage in physical exercise, increase the speed of metabolism, expel some toxins from the body, and at the same time ensure your inner comfort, do not have too much psychological pressure of arubina, and a positive and optimistic attitude is more conducive to the recovery of the disease.

Tuberous sclerosis can be relieved by drugs and surgery, but the pain caused by tuberous sclerosis cannot be eliminated at present, and there is no best way to do it. Tuberous sclerosis is a kind of genetic disease, and the most effective way to reduce the incidence of disease is to prohibit the marriage of close relatives, and to promote eugenics and dry mountain education for the sake of the happy life of future generations.