Comparison of liquid and gaseous states of a vaporized hydrogen peroxide sterilizer

To achieve the same sterilization effect, the concentration of the liquid state is 300 times that of the gaseous state.

The spores are heat-resistant. Role on hydrophobic and hydrophilic surfaces The low-temperature sterilization process (4-80°C) is completed during the fumigation process with very little residue (no need to re-clean) and no toxic by-products after fumigation (health & safety).

For other items (fixtures, electrical appliances, cleanroom wall panels, etc.), the VHP process is easy to verify (compliance with regulatory requirements, process control) and environmental (health & safety).

Good HEPA permeability (glass fiber) for HEPA and good sterilization of most microorganisms at low gas concentrations (1-2 mg L = 1000 ppm).

The time required for sterilization is short.

Cost savings (short downtime) formaldehyde issues and concerns Controversy and concerns about formaldehyde.

The gas is formed by heating a formaldehyde solution or formalin.

The action is slow and requires a long fumigation time.

Crystalline residue.

There are no publications that prove effective before and after sterilization.

It is very difficult to verify the sterilization procedure.

Personnel must be evacuated during fumigation (long downtime).

Highly toxic and classified as 'Class A' Substances that are carcinogenic and cause cell mutations.

Flammability. <>

They work differently, but at the same time, they all achieve sterilization, but the concentration of the liquid state will be much, much larger than that of the gaseous state.

Upstairs is about plasma sterilizers, which require a vacuum environment, not for space sterilization. Vaporized hydrogen peroxide space sterilization generally refers to the surface sterilization of clean spaces under atmospheric pressure. In terms of principle and method, there are two main types:

The first is to atomize the liquid hydrogen peroxide into small droplets of less than ten microns and suspend them in the air, which will fill the entire space with hydrogen peroxide, and the surface of the liquid layer of hydrogen peroxide will also be attached. Hydrogen peroxide is continuously introduced and its concentration is maintained, and after a certain period of time, it can be discharged by ventilation and other means. The second is to vaporize hydrogen peroxide into gas through the method of low-temperature vaporization, which is passed into the space to be sterilized, so that it reaches the appropriate sterilization concentration and is maintained for a period of time, and then ventilated and discharged.

From the above introduction, the second method has obvious advantages: the distribution uniformity of the sterilant is good (small droplets - gas); Short residual removal time; Low residue; The sterilant has light corrosion to the material; The amount of sterilant used is small.

It's only 5 points, I'll answer part of it, how big is it to sterilize a large space? I don't know if the following information is copied or not, just for reference.

When the sterilization chamber is pumped into about negative pressure by the vacuum pump, open the valve between the container containing hydrogen peroxide and the sterilization chamber, and the liquid hydrogen peroxide is heated and vaporized through the heating chamber cavity and diffuses to the entire space of the sterilization chamber; Hydrogen peroxide itself has a strong bactericidal effect, and can kill some bacteria and viruses on the surface of the treated items during the diffusion process of hydrogen peroxide; When a high-frequency voltage is added between the sterilization chamber and the mesh stainless steel electrode, the hydrogen peroxide gas in the sterilization chamber is dissociated into charged particles under the action of a high-frequency electric field, forming a plasma, and a large amount of ultraviolet rays generated during the plasma formation process directly destroy the genetic material of microorganisms; The intrinsic photolysis of ultraviolet photons breaks the chemical bonds of microbial molecules, and finally generates volatile compounds such as CO and CHX. Through the etching of plasma, that is, the active substances in the plasma react with the proteins and nucleic acids in the microorganisms, which can destroy the microorganisms and disrupt the survival function of the microorganisms, so as to achieve the purpose of sterilization. In this type of plasma, the electron temperature is high, while the ion temperature is close to room temperature, about 35 38 . This achieves the purpose of efficient sterilization without changing the structural properties of the sterilized items due to high temperature.

For large spaces, such as rooms larger than 100 cubic meters, a dry mist hydrogen peroxide sterilizer is usually used, which is fast, efficient and flexible. At present, the droplet diameter is less than 1 micron, and the disinfection and sterilization effect of 1000 cubic meters can be achieved at a time.

Can be contacted:

Hydrogen peroxide has a bactericidal effect due to its redox effect, especially for anaerobic bacillus.

The principle of action of hydrogen peroxide is the dissociation of highly active hydroxyl groups through complex chemical reactions, destroying cell membranes.

At the end of the 1980s, Steril Co of the United States first discovered that gas hydrogen peroxide can achieve the same sterilization effect at a lower concentration than liquid cracked bridge hydrogen peroxide.

In 1990, the vigorous gasification of hydrogen peroxide was officially approved by the EPA of the United States as a sterilant, and soon used in various banquet bird industrial fields.