Why is total bilirubin high Why is total bilirubin high?

or other metabolites in reticuloendothelial cells and hepatocytes. Bilirubin is a metabolite of heme in hemoglobin and other heme proteins in macrophages or other reticuloendothelial cells and hepatocytes. Brownish-yellow, mammal.

It is mainly excreted with bile. Elevated blood can cause jaundice. In liver function, total bilirubin is the sum of indirect bilirubin and direct bilirubin, and when either indirect bilirubin and direct bilirubin is elevated, it will cause total bilirubin to rise.

According to professionals from Shanxi CDC Liver Disease Diagnosis and Treatment Center, the best liver disease hospital in Shanxi, human red blood cells.

After death, indirect bilirubin is produced, which is converted by the liver into direct bilirubin, which then forms bile into the intestine and is finally excreted through urine and urine. If there is a problem in some of these links, the metabolic pathway of bilirubin will be interrupted, resulting in an increase in direct or indirect bilirubin, resulting in a high total bilirubin. What are the dangers of high bilirubin?

Bilirubin is the red blood cell in the blood.

Heme metabolized waste products. If the serum bilirubin is too high, it indicates abnormal information such as liver lesions or bile duct obstruction, and the level of serum bilirubin indicates the severity of the abnormality. If too many red blood cells are destroyed, too much indirect bilirubin is produced, which prevents the liver from fully converting it to direct bilirubin, and hemolytic jaundice occurs.

Elevated levels of total bilirubin can cause harm to the human body. So, what are the dangers of high total bilirubin? Clause.

1. When human hepatocytes are necrosis, the content of indirect bilirubin increases rapidly, and the liver cannot completely convert it into direct bilirubin, resulting in an increase in indirect bilirubin and total bilirubin, which will cause hemolytic jaundice. Clause.

2. When the liver is damaged, bilirubin cannot be converted into bile normally, which will cause hepatocyte swelling, resulting in bile duct compression, bile can not be discharged smoothly, so that the total bilirubin in the blood increases, resulting in hepatocellular jaundice. Clause.

3. If the biliary system does not operate smoothly, such as tumors and stones blocking the biliary tract, bile cannot be discharged smoothly, and the total bilirubin will also increase, and obstructive jaundice will occur in the human body. What should I do if my total bilirubin is elevated? High total bilirubin is recommended here.

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The lifespan of a person's red blood cells is generally 120 days. When red blood cells die, they become indirect bilirubin (SIB), which is converted to direct bilirubin (SDB) by the liver, which forms bile, is excreted into the biliary tract, and finally excreted in the stool. The sum of indirect bilirubin and direct bilirubin is total bilirubin (STB).

Disorders in any of these links can cause jaundice. If the red blood cells are destroyed too much and too much indirect bilirubin is produced, the liver cannot completely convert it into direct bilirubin, and hemolytic jaundice can occur; Hepatocellular jaundice occurs when hepatocytes are diseased, or because bilirubin cannot be converted into bile normally, or because hepatocytes are swollen, which compresses the bile ducts in the liver, obstructs the excretion of bile, and increases bilirubin in the blood. Once tumors or stones appear in the biliary system outside the liver, the bile duct will be blocked, and bile cannot be excreted smoothly, resulting in obstructive jaundice. Jaundice in patients with hepatitis is generally hepatocellular jaundice, which means that both direct and indirect bilirubin are elevated, while in patients with cholestatic hepatitis, direct bilirubin is predominantly elevated.

1) The normal value of total bilirubin is; The normal value of direct bilirubin is 0--6 mol l; Normal indirect bilirubin values are:

2) Elevated bilirubin is common for the following two reasons:

1.Liver disease.

Acute jaundice hepatitis, acute yellow liver necrosis, chronic active hepatitis, liver cirrhosis, etc.

2.Extrahepatic disease.

Hemolytic jaundice, transfusion reaction of blood group incompatibility, neonatal jaundice, cholelithiasis, liver cancer, pancreatic head cancer, etc.

There are many reasons for high total bilirubin in the body, first of all, it is excluded that the liver itself is a problem, such as severe liver disease, and it may also be a gallbladder disease, such as the most common cholecystitis, gallstones or inflammation of the common bile duct, etc., which may cause an increase in bilirubin, and a mild increase in bilirubin may also be related to their own anemia and blood drawing error, red blood cell rupture and other factors, pay attention to active examination.

Extended information: Total bilirubin, which includes indirect bilirubin and direct bilirubin, is primarily used to diagnose liver disease or biliary abnormalities. When this normal range is exceeded, total bilirubin is elevated.

Normal values are. Causes of elevation.

Since total bilirubin is the sum of indirect bilirubin and direct bilirubin, an increase in indirect bilirubin or an increase in direct bilirubin can cause an increase in total bilirubin.

1. Elevated total bilirubin and increased indirect bilirubin: When suffering from hemolytic jaundice, a large number of red blood cells are destroyed, and indirect bilirubin increases, which exceeds the conversion ability of the liver, so that indirect bilirubin is retained in the blood, thereby causing an increase in total bilirubin. It is generally common in hemolytic jaundice, blood transfusion reactions with blood group incompatibility, neonatal jaundice and other diseases.

2. Elevated total bilirubin and increased direct bilirubin: If there is a problem with the biliary tract, direct bilirubin cannot be fully discharged into the intestine, but reverses into the blood, resulting in an increase in direct bilirubin in the serum, and a high total bilirubin will increase, thus causing obstructive jaundice. Elevated total bilirubin due to these causes is common in biliary tract diseases such as cholecystitis and cholelithiasis.

3. Total bilirubin is elevated, both direct and indirect bilirubin are elevated: if there is a problem with the liver, that is, the liver cells are damaged, the liver's ability to convert indirect bilirubin into direct bilirubin decreases, which will cause the phenomenon that direct bilirubin and indirect bilirubin are high at the same time, and the total bilirubin is also high, that is, hepatocellular jaundice. When there are liver diseases such as acute jaundice hepatitis, acute yellow liver necrosis, chronic active hepatitis, and cirrhosis, it will cause an increase in total bilirubin.

Some people ask what is the cause of high total bilirubin direct bilirubin? What exactly causes it? Nowadays, there will always be high total bilirubin in our lives, when we have this situation, we should find out the cause, so as to gradually improve it in a reasonable way, if you want to know more, then read the following article.

Elevated total bilirubin is a cause that should be understood to see if it is related to certain diseases, such as elevated total bilirubin, which may be a sign of liver cell damage. When the liver is damaged, the liver's ability to convert indirect bilirubin into direct bilirubin decreases, which may lead to high levels of both direct bilirubin and indirect bilirubin. If there are these manifestations, we should pay attention to it, beware of liver diseases such as liver cirrhosis, chronic hepatitis, active hepatitis, etc., and timely target the lesions of the liver to prevent the continuous increase of total bilirubin and affect the health of the body.

In general, elevated total bilirubin is more common in biliary diseases such as cholelithiasis and cholecystitis, so finding that total bilirubin is elevated is the next step of examination to see if there are biliary-related diseases. If it is caused by biliary tract lesions, it is necessary to prevent cholelithiasis and cholecystitis from continuing to aggravate and endanger health.

Causes hepatocellular jaundice. Due to the high total bilirubin, bilirubin cannot be converted into bile normally, which will lead to liver cell lesions, or swelling, and the bile ducts in the liver are suppressed, which has a great impact on the cells, so it may develop hepatocellular jaundice.

Everyone will definitely not think that an ordinary high total bilirubin will bring such a big threat to physical health, so if you must pay attention to it when examining cadres, if the total bilirubin is high, ask the doctor in advance if you need drug intervention**, I hope the above content will help you.

The low protein value in normal people is mainly due to malnutrition. In general, paying attention to dietary improvement can increase the pre-protein value. In addition, nephritis may also cause low proprotein values.

Various liver diseases such as viral hepatitis, alcoholic liver, etc. It is clear that since the proprotein is synthesized by hepatocytes. If hepatocytes are damaged, natural proprotein synthesis decreases, and prealbumin decreases in 30% of patients with normal liver disease.

The value of albumin before cirrhosis after necrosis is almost zero. In cirrhosis, cell necrosis is mild and the proprotein does not change much.

In 30% of patients with eualbumin-normal liver disease, prealbumin is reduced, and prealbumin values are almost zero after necrosis. In cirrhosis, hepatocyte necrosis is mild, prealbumin does not change much, the prognosis is good, and when the disease improves, prealbumin also rises rapidly. Therefore, low prealbumin can indicate the degree of inflammation in the patient, and the patient must pay attention to it.

Soybeans and soy products are rich in protein, calcium, iron, phosphorus, B vitamins, moderate fat and a small amount of carbohydrates, which are very beneficial to protect the liver and supplement nutrition.

Most of the bilirubin in the body comes from the hemoglobin released by the lysis of senescent red blood cells, including direct bilirubin and indirect bilirubin, and there are many reasons for high bilirubin, mainly hepatocellular jaundice, hemolytic jaundice and obstructive jaundice.

Total bilirubin is made up of direct bilirubin and indirect bilirubin.

The total height, which is directly normal, is the indirect high.

The cause of indirect bilirubin elevation is mainly prehepatic, which is the excessive breakdown of hemoglobin or myoglobin.

Excessive activity, high fever, allergies to certain substances, etc. can occur.

The focus should be on checking the blood for hemolysis.

Hello! Bilirubin, a metabolite of red blood cells in the blood. A normal person produces 250 350mg of bilirubin per day, most of which comes from senescent red blood cells in the blood, and the rest comes from the bone marrow and liver.

Elevated bilirubin is seen in various types of jaundice.

The total bilirubin and indirect bilirubin are elevated, which belongs to the category of hemolytic jaundice. It is not known if you have taken certain hemolytic medications or foods while trying to get pregnant.

Due to the increase in metabilirubin, hepatocytes convert it into syncholirubin and excrete it into the intestinal lumen with bile, so the fecal bililogen and urobilinogen formed in the intestinal lumen and excreted by urine and urine also increase.

Judging from the information provided, the total bilirubin and indirect bilirubin are both high, which does not necessarily mean that there is any problem, and it is recommended to recheck it after a while.

If you have jaundice or fever or cardiac insufficiency or fatigue, if you are planning to get pregnant, it is recommended to check the hepatitis index, electrocardiogram or Holter electrocardiogram to rule out whether there is infection or fever, and recheck the indicators in a state of non-fatigue! Good luck soon**!

When I was younger, I also had high levels of bilirubin and couldn't donate blood, but I was healthy. I consulted a doctor and said that it was caused by too much fatigue and that I should rest more. Especially if you are planning to get pregnant, you should pay more attention to rest. Of course, it is best to go to the hospital for consultation.

Bile can secrete a pigment called bilirubin, which is an indicator of the body's health, and can also check whether an organ in the body is functioning properly. In the general medical report, you will see data on bilirubin. Some doctors look at the health index of the human body, mainly to see whether the bilirubin on the physical examination report is normal.

At present, people suffer from the condition of colds, which can also cause the occurrence of various diseases. In real life, people also pay more attention to their health. Over a period of time, a physical examination will be performed.

During the physical examination, people will do some liver tests, and at this time, bilirubin will be shown on the medical examination report. Some doctors look at the medical checklist and prescribe medication to the patient.

An increase in bilirubin will lead to an increase in other indicators, and as a result, our body will not be able to maintain health. For example, sometimes there is a problem with the liver, which can cause a rise in bilirubin. Some other cellular indices in the body also rise, such as the rise in alanine aminotransferase and aspartate aminotransferase.

After our physical examination, when we get the physical examination form, we should also pay attention to the bilirubin data and ask the doctor carefully.

If there is a problem with the biliary tract, it will cause an increase in bilirubin, and it will be worse. It is also possible to observe the person's appearance to indicate the rise in bilirubin, for example, the face is yellow, and it is necessary to consider whether there are some problems with the biliary tract and pancreas.

Direct bilirubin elevated.

An increase in indirect bilirubin, after a series of changes, produces direct bilirubin. One of the factors that increase direct bilirubin is when the biliary tract is blocked and the excretion is not good. In terms of diet, there are also certain factors.

Reduce alcohol consumption and avoid a rise in bilirubin. When choosing food, don't choose some greasy foods, eat some light foods.

There are also certain requirements for people's lives. It is not recommended for people to exercise vigorously and drink a lot of alcohol, etc., otherwise, it will cause the bilirubin in the body to rise. When we are exercising, we must master the rhythm and exercise appropriately.

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