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Methylprednisolone [English name] sou-medrol
Category] Adrenocorticotropic hormone and adrenocorticotropic hormone drugs.
Synonyms] sodium succinate-6 methylprednisolone; Amber damposaurus; methylprednisolone; Methylprednisone sodium succinate , methylprednisolone needle.
Foreign name] sou-medrol
Indications] Agree with the upstairs.
Dosage and usage] intravenous injection: once a day, each kilogram of body weight for severe patients can be used Organ transplant rejection (especially kidney transplantation) can be administered intravenously within hours and continued** until the condition is stable, generally not more than an hour. Immune syndrome is usually given separately, or every other day, or every other day.
The initial use of this product should be completed within minutes, and the speed can cause arrhythmia.
Precautions] 1Less water and sodium retention than prednisone. Occasionally, it can induce infection, peptic ulcer, elevated blood sugar, mental abnormalities, moon face, hirsutism, azolus, etc.
2.Contraindications are the same as corticosteroids. Large doses ( and rapid injections or intravenous infusions (eg, within minutes) can cause arrhythmias and even circulatory collapse.
Osteoporosis can occur in older users.
Specifications】 Powder injection
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It is mainly used for organ transplantation, rejection immune syndrome, immune syndrome, suppression of immunity, acute adrenal insufficiency, surgical shock, etc.
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Hello! Methylprednisolone is the trade name of methylprednisolone sodium succinate for injection manufactured by Pfizer Pharmaceutical, which is its unique trade name. A glucocorticoid drug. The domestic one is Tianjin Pharmaceutical Co., Ltd., and the trade name produced by Jiaozuo Pharmaceutical Co., Ltd. is the same kind of drug
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Methylprednisolone sodium succinate.
Methylprednisolone (methylprednisolone sodium succinate for injection) is indicated for a treatment of the drug unless it is used as an alternative for certain endocrine disorders**.
Ingredients: The main ingredient of this product is: methylprednisolone sodium succinate.
Chemical name: 11,17,21-trihydroxy-6-methylpregninosteroid 1,4-diene, 3,20dione, sodium 21-succinate.
Composition: b].
The 40mg specification of this product, each 1ml double-chamber bottle contains diluent solution (9mg of benzyl alcohol and water for injection), and the lower chamber is methylprednisolone sodium succinate and auxiliary materials: sodium dihydrogen phosphate monohydrate, disodium hydrogen phosphate (anhydrous), lactose, 10% sodium hydroxide solution and water for injection.
This product is 125mg specification, each 2ml double-chamber bottle shirt contains diluent solution (benzyl alcohol 18mg and water for injection), and the lower chamber is methylprednisolone sodium succinate and excipients: sodium dihydrogen phosphate monohydrate, sodium dibasic phosphate (anhydrous % sodium hydroxide solution and water for injection.
This product is 500mg specification, including a bottle of sterile powder, and 1 bottle of diluent (containing benzyl alcohol and water for injection). Among them, the sterile powder contains methylprednisolone sodium succinate and excipients: sodium dihydrogen phosphate monohydrate, sodium dibasic phosphate (anhydrous % sodium hydroxide solution and water for injection.
The above content reference: Encyclopedia - Methylprednid.
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The maximum pharmacological effect occurs after the peak blood concentration, suggesting that most of its action is by altering the enzyme.
This product is methylprednisolone for intravenous and intramuscular injection, which is a synthetic glucocorticoid. This highly concentrated aqueous solution is particularly suitable for disease states that require a strong, fast-acting hormone**. Methylprednisolone has strong anti-inflammatory, immunosuppressive and anti-allergic activities.
Glucocorticoids diffuse through cell membranes and bind to specific receptors in the cytoplasm. This conjugate then travels into the nucleus to bind to DNA (chromosomes), initiating transcription of mRNA and the synthesis of enzyme proteins that are thought to ultimately enable glucocorticoids to exert their many systemic effects. Glucocorticoids play an important role not only in inflammatory and immune processes, but also in carbohydrate, protein, and fat metabolism, and also on the cardiovascular, musculoskeletal and central nervous systems.
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Methylprednisolone is a glucocorticoid, *** there are many.
As follows:
Hypercortical syndrome. Full moon face, buffalo back, high blood pressure, hirsutism, diabetes, **thinning, etc. It is caused by GCS and metabolic disorders.
Induces or exacerbates infection. The main reason is that hormones reduce the body's resistance to pathogenic microorganisms.
Induces or worsens ulcer disease.
Induces high blood pressure and arteriosclerosis.
Inhibits children's growth and development.
Other: Negative nitrogen balance, increased appetite, hypocalcemia, hyperglycemic tendency, peptic ulcer, euphoria.
Necrosis of the femoral head.
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