What are the main manifestations of acral scleroderma?

Expert introduction: scleroderma is a systemic connective tissue disease with sclerosis of various systems, which is clinically characterized by swelling, hardening, posterior muscle atrophy, and bone damage. So, in response to this problem, the following experts will give you a detailed introduction.

There are two types of scleroderma, localized scleroderma and systemic scleroderma, and localized scleroderma is mainly confined to **, internal organs are generally not affected, and the prognosis is better. Systemic scleroderma is a widely distributed ** sclerosis, which can affect all organs of the body and has a poor prognosis. Whereas, acral scleroderma is a type of systemic scleroderma.

Acral scleroderma is mainly manifested as symmetrically starting from the ** of the hands and feet. The initial symptom is Raynaud's phenomenon of the hands, which is often paroxysmal pallor, chills and numbness of the hands and fingers when the spirit is agitated, and it is heavy in winter and light in summer. Patients may have a low-grade fever and joint aches.

At the beginning of the lesion, the fingers are non-pitting and swollen, the skin lines gradually disappear, ** gradually become hard and tight, and the surface has a waxy luster, which cannot be pinched by hand. The fingers gradually become thinner, the phalanges are shortened, and the skin lesions gradually develop on the forearms, elbows, neck, and upper trunk, and the lower trunk and lower extremities are milder. The back of the face is taut and thin, the face is emaciated, the expression is lacking, the nose is sharpened, the mouth opening is limited, and the frenulum is shortened.

Finger tips** may be calcified, necrosis and ulceration may occur, and healing is not readily available. In the late stage, the sclerosis is reduced, but the subcutaneous tissue is significantly atrophied, like a layer of **clinging to the bone, the pigment diffusely increases, accompanied by depigmented plaques, and the telangiectasia is significant. The above experts have given you a detailed introduction, I hope the above content can help you, the symptoms of acral scleroderma are not only manifested in **, but also harm internal organs, including the digestive system, cardiovascular system, respiratory system, urinary system and neuropsychiatric system.

The early symptoms of scleroderma are mainly manifested as whitening, redness, purple, muscle tenderness, joint pain, numbness, swelling, erythema, muscle weakness, edema, itching, stereotyped face, inability to clench fists with both hands, morning stiffness of finger joints, cyanosis, finger movement disorders, unable to be lifted normally, hardening, texture fading and other symptoms, and if the situation is serious, it will also cause lesions of the kidneys, heart and lungs, and even life-threatening if it is not timely.

Scleroderma is generally caused by factors such as abnormal humoral immunity, congenital heredity, abnormal hormone secretion levels, environmental influences, etc., early scleroderma can be treated with some drugs that dilate blood vessels and improve microcirculation, such as aspirin, dipyridamole, etc., and can also be improved with some drugs such as glucocorticoids or immunosuppressants, such as methotrexate, cyclohorin, etc., and you can also eat some drugs that can increase nutrition and elasticity, such as penicillamine, Usually pay attention to keep the best clean and hygienic, but also do a good job of keeping yourself warm, which is helpful for diseases.

The main manifestation of patients is symmetrical ** sclerosis, the common first symptom is Raynaud, and the phenomenon is after cold or nervousness. Fingers** first grow white and then turn red and purple, accompanied by pain and stiffness, etc., which may injure the gastrointestinal tract, waste heart, kidneys and other multi-system lesions. According to the cumulative regurgitation, it can be divided into focal scleroderma and systemic.

The main symptom of focal scleroderma is ** lesions, which generally do not harm internal organs, and are mainly divided into guttate plaques and bands. Initially, there is one or more reddish or purplish-red edematous patchy lesions. It is often oval or irregularly shaped, and the size of the coin is also larger, and after weeks or months, it develops into ivory white or yellowish-white with a concave lesion in the middle, and the surrounding lesions are large or lilac, and the surface is as hard as leather, and as the disease progresses, the degree of hardening decreases, and white or light brown may appear.

It is more common on the trunk, more common in adults, and more common in children with partial depression when the face occurs. Systemic scleroderma is more common in women, and the internal organs are damaged, and the condition is relatively reduced. Patients with scleroderma can present with a variety of pulmonary pathologies such as pulmonary interstitial fibrosis, pulmonary hypertension, alveolitis, and pleural effusion.

In most patients, early symptoms are not obvious. Dyspnea after labor, shortness of breath and dry cough after activity also have a small number of patients with rapid onset and poor prognosis, lung lesions are one of the main causes of death, asymptomatic lesions in the early stage, and a variety of cardiac lesions can be found after systematic examination, often manifested as shortness of breath, chest tightness, palpitations, precordial pain, arrhythmia, etc.

The early symptoms of scleroderma are mainly manifested as whitening, redness, purple, muscle tenderness, joint pain, numbness, swelling, erythema, muscle weakness, edema, itching, stereotyped face, inability to clench fists with both hands, morning stiffness of finger joints, cyanosis, finger movement disorders, unable to be lifted normally, hardening, texture fading and other symptoms, and if the situation is serious, it will also cause lesions of the kidneys, heart and lungs, and even life-threatening if it is not timely.

Scleroderma is generally caused by factors such as abnormal humoral immunity, congenital heredity, abnormal hormone secretion levels, environmental influences, etc., early scleroderma can be treated with some drugs that dilate blood vessels and improve microcirculation, such as aspirin, dipyridamole, etc., and can also be improved with some drugs such as glucocorticoids or immunosuppressants, such as methotrexate, cyclohorin, etc., and you can also eat some drugs that can increase nutrition and elasticity, such as penicillamine, Usually pay attention to keep the best clean and hygienic, but also do a good job of keeping yourself warm, which is helpful for diseases.

Scleroderma is a connective tissue disease characterized by inflammation, degeneration, thickening, and fibrosis leading to hardening and atrophy, and can cause multisystem damage. Among them, systemic sclerosis can also affect internal organs such as the digestive tract, lungs, heart and kidneys, in addition to degenerative lesions of the synovial membrane and digital (digital) arteries.

2.The first symptom of scleroderma is Raynaud's phenomenon, which is when the limbs are cold or emotional, the skin color turns white due to the rapid constriction of blood vessels, then turns purple due to the lack of oxygen in the blood, and finally turns red due to reflex dilation.