What are the side effects of Nimisul granules?

Generally speaking, the known adverse reactions of a drug or other *** will be described in the drug instructions, please carefully read the instructions under the [adverse reactions] [contraindications] [precautions] [children's drugs] [elderly patients] [women and lactating women] and other contents. The following is the relevant content of the instruction manual of Nimishu granules:

Adverse reactions] The main ones are: heartburn, nausea, and stomach pain, but the symptoms are all mild and short, and rarely need to be interrupted**. Rarely, people develop an allergic rash after taking the drug.

Even if the use of nimesulide does not produce the above***, it should be noted that this product, like other non-steroidal anti-inflammatory drugs, may cause dizziness, drowsiness, gastric ulcers or gastrointestinal bleeding and Stevens Johnson syndrome.

Contraindications] It is forbidden for those who are allergic to this product, acetylsalicylic acid or other non-steroidal drugs. Patients with active gastrointestinal bleeding and active peptic ulcer are contraindicated. Contraindicated in patients with severe hepatic insufficiency, severe renal dysfunction (creatinine clearance 30 mL min )

Precautions】 Nimesulide should be used with caution in the following patients: patients with a history of bleeding; Patients with gastrointestinal disorders; Patients receiving anticoagulants** or taking antiplatelet aggregation medications. Because this product is mainly excreted through the renal system, if renal insufficiency, the dose of the drug should be reduced according to the glomerular filtration rate.

It should be contraindicated in patients with renal failure. If vision loss occurs after concomitant use of other NSAIDs, the ophthalmologic examination should be discontinued** and an eye examination should be performed.

Please read the instructions carefully and use as directed by your healthcare professional.

Children] For children over 1 year of age only, the dose is 5 mg kg body weight per day, divided into 2 to 3 doses, the maximum dose does not exceed 100 mg, 2 times a day. For antipyretic, the course of treatment does not exceed 3 days. For rheumatism, the course of treatment should be as directed by a doctor.

Medication for elderly patients] The annual medication dose of patients should be strictly in accordance with the doctor's regulations, and the doctor can appropriately reduce the dosage according to the situation.

Pregnant and lactating women] Nimesulide, like all new drugs, is not recommended for use during pregnancy if it has not been tested to confirm whether nimesulide is toxic to the fetus. In cases where it is not clear whether nimesulide is possible to be excreted from the body through breast milk, it is also not recommended to use this drug during breastfeeding.

Drug Interactions] This product may cross-react with aspirin and other non-steroidal anti-inflammatory drugs, so it is forbidden for patients who are allergic to these drugs; This product is a highly protein-binding drug, so it may replace other protein-binding drugs; If vision loss occurs after taking other non-steroidal anti-inflammatory drugs, it should be stopped** and an eye examination should be performed.

Generally, *** are gastrointestinal, nausea, vomiting, this kind of thing.

Summary. Hello, dear. Your questionThe efficacy and effect of Nimesulide Granules, as follows the effect of Mesulide is a non-systemic anti-inflammatory drug, which exerts anti-inflammatory, analgesic and antipyretic effects by selectively inhibiting cyclooxygenase-2 (COX-2) and inhibiting the release of mediators in the inflammatory process.

Nimesulide is generally used for anti-inflammatory, anti-rheumatism, analgesia, and antipyretic, such as osteoarthritis, rheumatoid arthritis, toothache, rhinitis, tonsillitis and respiratory tract infections. Indications: This product has a strong anti-inflammatory effect, which can be used for joint and connective tissue diseases such as osteoarthritis, rheumatoid arthritis and other inflammatory arthritis, and can also be used for bursitis, myophylitis, synovitis, frozen shoulder and other soft tissue rheumatism. This product has antipyretic and analgesic effects, and can be used for toothache, dysmenorrhea, postoperative pain and cancer pain, etc., and can also be used for rhinitis, laryngitis, otitis, tonsillitis and respiratory tract infections, suitable for pain caused by joint and connective tissue diseases, articular and soft tissue injury symptoms related to toothache, dysmenorrhea, postoperative pain and cancer pain.

Fever due to rhinitis, laryngitis, otitis, tonsillitis, and respiratory tract infections.

Hello, dear. Your questionThe efficacy and effect of Nimesulide Granules, as follows the effect of Mesulide is a non-systemic anti-inflammatory drug, which exerts anti-inflammatory, analgesic and antipyretic effects by selectively inhibiting cyclooxygenase-2 (COX-2) and inhibiting the release of mediators in the inflammatory process. Nimesulide is generally used for anti-inflammatory, anti-rheumatism, analgesia, and antipyretic, such as osteoarthritis, rheumatoid arthritis, toothache, rhinitis, tonsillitis and respiratory tract infections.

Indications: This product has a strong anti-inflammatory effect, which can be used for joint and connective tissue diseases such as osteoarthritis, rheumatoid arthritis and other inflammatory arthritis, and can also be used for bursitis, myophylitis, synovitis, frozen shoulder and other soft tissue rheumatism. This product has antipyretic and analgesic effects, and can be used for toothache, dysmenorrhea, postoperative pain and cancer pain, etc., and can also be used for rhinitis, laryngitis, otitis, tonsillitis and respiratory tract infections, suitable for pain caused by joint and connective tissue diseases, articular and soft tissue injury symptoms related to toothache, dysmenorrhea, postoperative pain and cancer pain. Fever due to rhinitis, laryngitis, otitis, tonsillitis, and respiratory tract infections.

Other effectsNimesulide is a selective inhibitor of COX-2, and studies have confirmed that the drug can enhance the effect of chemoradiotherapy, and when used in combination with anti-tumor drugs, it can inhibit the growth, invasion and metastasis of gastric cancer and esophageal cancer cells. Keep it away from children and do not recommend medication to others based on their experience. Nimesulide may have contraindications or risk of serious adverse reactions when used in special populations, and can interact with some drugs and interact with each other, please be sure to inform your doctor before taking the drug, and consult the doctor whether you can use the drug and how to use it.

Summary. Hello dear, Nimesulide has antipyretic, analgesic and anti-inflammatory effects, and can be used for chronic arthritis-related pain, such as rheumatoid arthritis and osteoarthritis.

Hello dear, Nimesulide has antipyretic, analgesic and anti-inflammatory effects, and can be used for chronic arthritis-related pain, such as rheumatoid arthritis and osteoarthritis.

When applying Nimesulide granules, there are some precautions: 1. Do not overdose, can not be used too frequently. Because excessive use and too frequent use can lead to a significantly increased risk of adverse reactions in patients.

2. It is necessary to know what are the adverse reactions of the drug, as for the common adverse reactions, including kidney damage, liver damage, and even adverse effects of heart function.

Suggestion: Analysis: Hello, Nimesulide granules are antipyretic analgesics. It has anti-inflammatory, analgesic and antipyretic effects.

Guidance: For chronic arthritis, pain and inflammation after surgery and acute trauma, pain caused by inflammation of the ear, nose and pharynx, dysmenorrhea, fever caused by upper respiratory tract infection and other symptoms.

Nimesu granules have a long antipyretic duration of up to 12 hours, and many parents like to use them, but it is relatively large. Many doctors also like to use it (because it is larger, European and American countries are not used as antipyretics for children. Commonly used antipyretic options in pediatrics:

Ibuprofen suspension or acetaminophen dropsTrade name : Motrin; or "Tylenolin" is relatively safe and effective Nimesulide can cause damage to the central nervous system and liver in children, so it must be used with caution. Generally, tertiary hospitals do not use it for children.

Cases of damage to the central nervous system and liver caused by the drug are not uncommon.

According to the report of the Adverse Drug Reaction Monitoring Center, there have been thousands of adverse events and even several deaths in the use of nimesulibib erection for analgesic fever in children. After the CCTV warning, the relevant people of the Shanxi Provincial Adverse Drug Reaction Monitoring Center also confirmed that since 2004, the center has received more than 3,300 reports of adverse reactions to antipyretic and analgesic drugs, and many cases of adverse reactions involve children. Among them, there were 86 cases of nimesulide, a children's antipyretic drug, which was the focus of attention, and the dosage forms were mainly tablets and granules.

The new edition of Pharmacology contains a note on nimesulide: it is mainly used for rheumatoid arthritis and osteoarthritis, dysmenorrhea, postoperative pain and fever, and it is not marked that it can be used in children. It is not known why Nimesulide is available for children in China.

Hello, are Nimesu granules antibacterial?

It is not suitable for young children. For the time being, it is not available in China and is forbidden to be taken by children under the age of 12 abroad.

This drug has been banned for more than half a year, you only know now.