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Questions about penicillin skin test. As we all know, in order to prevent the occurrence of penicillin allergic reactions, especially anaphylactic shock, our pharmacopoeia stipulates that a skin test must be done before using penicillin. Penicillin skin test plays an important role in the occurrence of anaphylactic shock, but a negative skin test cannot rule out the possibility of an allergic reaction.
Penicillium thiazole-polylysine, benzylpenicillin thiazole sodium or penicillin may be used to detect antibodies to the size of the allergic reaction to the antigen of the epitope, which is highly accurate and safe, but the first two are currently lacking in China. We mostly take penicillin G sodium, dissolve it in sodium chloride injection, and prepare it into a 500 unit ml solution. Made aseptically and can be used for one week at 4 times and on the same day at room temperature.
Penicillin skin reagents produced by manufacturers can also be purchased directly. Commercially available penicillin skin reagent contains 2500 units of penicillin sodium per vial, when used, dissolved and diluted with 5ml of sterilized normal saline, and injected intradermally, if there is local redness and swelling after 20 minutes, pseudopodia, the diameter of the dermatom is more than 1cm, or symptoms such as dizziness, chest tightness and itching all over the body are positive. In addition, it is advisable to prescribe a skin test of which penicillin should be used (at an optional concentration of 300 g ml).
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Take 800,000 penicillin as an example:
Penicillin 800,000u bottle: 50u
800,000 penicillin plus normal saline dissolved to 4ml; (200,000 U ml) take the upper liquid normal saline to 1ml; (20,000 u ml).
Take the upper liquid normal saline to 1ml; (2 thousand U ml).
Take the upper liquid normal saline to 1ml; (500u ml) for skin test (i.e. 50u).
1.6 million penicillin plus normal saline dissolved to 4ml; (400,000 U ml) take the upper liquid normal saline to 2ml; (20,000 u ml).
Take the upper liquid normal saline to 1ml; (2 thousand U ml).
Take the upper liquid normal saline to 1ml; (500u ml) for skin test (i.e. 50u).
4,000,000 and so on.
The main thing is a matter of calculation.
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Penicillin skin test solution configuration: 400,000 units of penicillin bottle into 2ml of normal saline, diluted to 200,000 per milliliter of penicillin g.
1) Take the upper solution and add normal saline to 1ml, then each ml contains 20,000 units of penicillin g;
2) Lift water to 1ml before taking the liquid and adding normal salt, then each ml contains 2000 units of penicillin;
3) Take the liquid or add normal saline to 1ml, then each ml contains penicillin g 200 units or 500 units. The solution needs to be mixed well each time it is prepared.
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800,000 units of penicillin are configured into one milliliter containing 400 units of skin test solution.
Hello, first of all, the total amount of fibrous is 800,000 penicillin, and then the final prepared skin test solution contains 500 units of penicillin skin test solution, and one skin chuck is injected into milliliters, so the penicillin content in one skin chuck is 50 units. The first step is to take 800,000 units of penicillin, open it vertically, and then dissolve it with four milliliters of normal saline, at this time each milliliter is 200,000 units of penicillin. In the penicillin test, and then add milliliters of normal saline, which is equal to 20,000 units of skin test solution, and then draw milliliters, and then add milliliters of normal saline, which is equal to 2000 units, and then we pump milliliters and add milliliters of normal saline, which is equal to 500 units, at this time the penicillin skin test solution is prepared.
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The optimal concentration of penicillin skin test solution is 400 ml per mL, and the volume of each injection of the pichu is in mL, and the dose of 20 units is optimal.
Penicillin is a commonly used antibacterial drug, its biggest *** is allergic reaction to shock, in order to prevent the occurrence of allergic reactions, you must do a skin test before use, and the skin test result is negative before use. And the time of occurrence of allergic reactions varies from person to person, some will have allergic reactions immediately when using penicillin, and some will even appear after 2 to 20 days in the case of continuous medication.
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Penicillin skin test dosage: 100 500U per milliliter of penicillin G saline solution is the standard. i.e., intradermal injection, containing penicillin 10 50u
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Hello, the preparation of penicillin skin test solution is generally required at 200 units per milliliter to be normal. The specific method is recommended to follow the doctor's instructions in a timely manner, and I hope to help you.
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Penicillin skin test solution: 20 50U
Penicillin injection volume: 150 u
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Summary. 1.8 million units of penicillin bottles were filled with 4 milliliters of normal saline and diluted to 200,000 units of penicillin per milliliter. 2 Take a milliliter of the liquid and add normal saline to 2 milliliters, then each milliliter contains 20,000 units of penicillin.
3 Take the upper milliliter and add normal saline to 2 milliliters, then each milliliter contains 2000 units of penicillin. 4 Take the upper milliliter or milliliter plus normal saline to 2 milliliters, then contain 200 units of penicillin or 500 units per milliliter. 1
5ml syringe with 2ml penicillin skin test solution, how to mix it most accurately?
5ml syringe with 2ml penicillin skin test solution, how to mix it most accurately?
1.8 million units of penicillin were injected into 4 milliliters of normal saline and diluted to 200,000 units of penicillin per milliliter. 2 Take a milliliter of the liquid and add normal saline to 2 milliliters, then each milliliter contains 20,000 units of penicillin. 3 Take 2 ml of the upper liquid and add normal saline to 2 ml, then each ml contains 2000 units of penicillium phlogistin.
4 Take the upper milliliter or milliliter plus normal saline to 2 milliliters, then contain 200 units of penicillin or 500 units per milliliter. 1
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Preparation of penicillin skin test solution: (take 800,000 units as an example).
1. Add 4ml of normal saline (200,000U per ml) with 800,000 units of penicillin 2, take the upper solution and add normal saline to 1ml (Jingsen contains 20,000U per milliliter of Liangjiaomu) 3, take the upper solution and add normal saline to 1ml, that is, the skin test solution (500U per ml).
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a.Steamed open stove mu distilled water.
b.Glucose.
c.Water for injection.
d.Equilibrate the salt solution.
e.Saline.
Correct answer to the case of Tsui Sen: e
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