What are the reasons for the rare patients in the world, who have had dwarfism and gigantism?

This man is Raynal. Since he was a child, his height was abnormal, his hands and feet were very large, and later the doctor diagnosed him with dwarfism, and when he became an adult, he suffered from gigantism, and later examined that he had a pituitary tumor, excessive secretion of growth hormone, and too fast growth.

The reason is that I have been diagnosed with these two symptoms since I was a child, but when I was young, it was dwarfism that started the effect first, and when I grew up, it became good because of the effect of gigantism.

Answer]: A growth hormone and thyroid hormone have an important role in the growth and development of the body, the former can promote the liver and many other organs to secrete growth factors, but also promote the growth of long bones, the latter not only promotes the growth of the body, but also has a great impact on the development of the central nervous system, so if the lack of thyroid hormone is stimulated in embryonic and early childhood, resulting in disorders of nervous system and bone development, it will cause short stature and mental retardation, which is called cretinism, so choose B for 2 questions. Lack of growth hormone in childhood, only short stature will appear, and intelligence is staring at the trousers, calling it dwarfism, so 1 question choose A.

He has passed away. Since the age of 21, his dwarf problem has not existed, and gigantism has caused damage to his spine and he will eventually be bedridden.

Because he was riddled with illness, he unfortunately passed away in the end, but what happened to him is worthy of people's sympathy.

Later, the situation was not very good, the person's physical illness was very serious, ** was also very troublesome, and he endured a lot of pain, which was not easy.

Like dwarfism and gigantism are now very rare, but it is not non-existent on the earth, according to historical records, a boy born in Austria in 1899 went through two particularly strange stages, when experts investigated the boy's family, and found that the boy's family is normal, and the height is also normal, but the child's development has been much slower than his peers since he was a child, and his height did not exceed 1.5 meters when he was 18 years old, but when he was 21 years old, His height suddenly grew to 2.1 meters, what is going on?

At that time, the little boy wanted to join the army, but the physical examination did not pass, because his height was only 122 cm at the time, but the little boy did not give up, and when he went to participate in the physical examination in the second year, the height of the test showed that it was only 127 cm, and later the experts found a data from the boy's physical examination report, this data is very abnormal, that is, this little boy, the ratio of his foot length and height is not normal, the ratio of normal people is 7:1, but the ratio of this child is 41. Many people think that such an exaggerated proportion, however, it is not normal to have dwarfism.

Later, when the little boy was 21 years old, his body changed dramatically, that is, his height suddenly soared, according to records, at the age of 21, the little boy's height has grown from the original 127 cm to 215 cm, a length of nearly a meter or so, of course, the sudden growth in height is definitely not suitable for the little boy, and the body can not bear it, which caused his spine to bend, and later the little boy was unable to walk upright normally, Generally speaking, it is unlikely that a person wants to grow taller after adulthood, but why can he grow so tall?

Because the height is very tall, the little boy is also very painful, so the little boy sought the help of experts, and later in the research of relevant scientists, the little boy found that there is a benign tumor in the pituitary gland, and the key to the rapid increase in the height of the little boy is on this tumor, and his continuous growth leads to the little boy's pituitary gland is constantly squeezed.

It causes the pituitary gland to secrete abnormal growth hormone at a normal age, so this can explain why the little boy was very short at the beginning, but then suddenly grew taller, but in human history, the example of this little boy who was very short before and then suddenly grew taller is too rare, I am afraid that there is only one such case in the entire human history.

And later, because the little boy died, his body was also buried, and scientists had no way to study his body, so this also became a very magical case in history. Since then, there have been no examples of dwarfism and gigantism at the same time.

Because his physique is very special, and some of his things are very sensitive, eating these things will change his physiological structure.

For dwarfism and gigantism, I believe everyone is familiar with it, after all, these are two very extreme conditions, dwarfism can make a person extremely short, and gigantism can make a person very tall. In general, it is not possible for these two conditions to occur in one person at the same time. But, you know what?

How is it that a man grows from a "dwarf" to a "giant", that is, he suffers from both diseases?

The man's name was Adam Raynal and he was born in 1899 in the Austro-Hungarian Empire. It is understood that his parents' height is normal, and neither of them is sick. However, Adam Rennal has been stunted since birth and is significantly shorter than his peers.

When Adam Renard was 18 years old, he wanted to sign up for the army, but he was turned away for the simple reason that he was not the height standard to join the army. Adam Raynal's medical check-up form clearly reads: 122 centimeters.

Raynald was not convinced, and a year later, he signed up for the army again.

Dwarfism is characterized by growth retardation and short stature, but intelligence is normal. In this way, Renard is indeed suffering from dwarfism. However, there is an extremely "abnormal" data on the physical examination form submitted by Rennal when he joined the army, and the physical examination form for his first year in the army reads:

The length of the foot is 28cm. However, his second year's physical examination form stated: the length of the foot is 33cm.

Obviously, Raynal's foot length did not match the length of his foot, and even exceeded the foot length of many tall people. Sure enough, when Raynal was 21 years old, he began to grow like crazy, and by the time he was 31, he had reached 219cm tall. Later, Raynal suffered from complications such as diabetes, and eventually he died in 1950 at the age of 51.

First dwarfism, and then gigantism, the pain of these two diseases is inflicted on a person at the same time, and you can imagine how painful Rennal must be.

In the sci-fi ** "Gulliver's Travels", the protagonist is both a giant in Lilliputian and a dwarf in the land of giants, and we all know that in real life, dwarfs and giants are two completely opposite sides.

So, is there a special situation that can make one be both a dwarf and a giant? This strange thing happened to a patient named Adam Rainer.

Adam was born in Graz, Austro-Hungarian Empire in 1899, to normal parents, but Adam not only grew slower than other children, but was also very short, and given the limited medical technology at the time, it was not known that Adam was actually suffering from dwarfism.

It wasn't until the outbreak of World War I that Adam wanted to join the army, and during the medical examination, Adam was diagnosed with dwarfism, when Adam was 18 years old, but he was only 122 centimeters tall.

In real life, dwarfism is also known as short stature, which is a disease caused by genetic abnormalities, insufficient secretion of growth hormone, skeletal system, etc., usually manifested by slow body development, short stature, and so on.

Although dwarfism does not cause intellectual deficits, it can lead to problems such as disproportionate body development and naïve facial appearance.

But the strange thing is that Adam's foot length and height are not proportional, and the ratio of normal people's foot length to height is one to seven, but Adam has reached one to four.

What's even more incredible is that Adam's height suddenly broke the limit, and his height grew from 122 centimeters to centimeters at once.

Although I was happy to suddenly grow to a centimeter, Adam also had problems, his body looked obviously uncoordinated, and his spine was severely scoliosis, which also made Adam unable to walk normally.

After an examination at the hospital, the doctor found that Adam had a benign tumor on his pituitary gland, and the compression of the tumor caused the pituitary gland to secrete excessive growth hormone, causing Adam to eventually suffer from gigantism.

Although Adam eventually underwent surgery to remove the tumor, sadly, doctors found that Adam's gigantism had not gone away, only slowed the rate of growth.

On March 4, 1950, at the age of 51, Adam died at the age of 234 centimeters, and Adam was the first person in the world to suffer from both dwarfism and gigantism.

In the sci-fi ** "Gulliver's Travels", the protagonist is both a giant in a small country and a dwarf in a large country. We all know that in real life, dwarves and giants are the complete opposite.

In order to alleviate the pressure on his bones caused by his height growth, he also underwent several surgeries, but doctors could not completely help him eradicate the lesions, after all, medical technology was not so advanced at that time.

Because of these two diseases, Adam's health was very poor, he was inconvenient, he had a large tumor, and he also suffered from high blood pressure, and he died suddenly in his sleep.