What causes gout? How gout is caused

Gout, also known as "hyperuricemia", is a type of arthritis caused by the accumulation of uric acid due to the impaired metabolism of purine substances in the human body.

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Generally speaking, gout can be caused by dietary habits, weather changes such as sudden changes in temperature and pressure, medications, trauma and other aspects. There are many causes of gout. Physiologically, the cause of gout is a disorder in the metabolism of a substance called purines in the body, and the synthesis of uric acid (increased or decreased excretion, resulting in hyperuricemia, when the blood uric acid concentration is too high, uric acid is deposited in the joints, soft tissues, cartilage and kidneys in the form of sodium salt, causing foreign body inflammation in the tissues to form gout.

Gout may be caused by eating too many high-purine foods, drinking alcohol for a long time, and abnormal purine metabolism.

1. Eating too much high-purine food: Gout is a rheumatic immune disease, if you eat too much high-purine food in your daily life, such as seafood or animal offal, etc., it will induce gout disease.

2. Long-term drinking: wine contains a large amount of alcohol and ethanol and other substances, after entering the body, the end products of ethanol metabolism will be discharged through the kidneys, and in the process of excretion, the number of uric acid excretion from the kidneys will be reduced to achieve the symptoms of elevated uric acid.

3. Abnormal purine metabolism: When there is more and more uric acid in the body, it will cause abnormal purine metabolism and induce gout disease.

It is necessary to use colchicine tablets, ibuprofen sustained-release capsules, bring western capsules and other drugs under the guidance of a doctor** disease. It is known that gout is mainly caused by abnormal purine metabolism, which can lead to local joint pain, swelling, etc., which can be relieved by drugs, but can not, colchicine, sodium bicarbonate tablets, diclofenac sodium** can be used to relieve symptoms during acute attacks, usually pay attention to a reasonable diet, avoid the intake of foods containing more purines, drink more water, and pay attention to keeping warm. Patients should go to the rheumatology and immunology department of a regular hospital in a timely manner.

Gouty arthritis is mainly due to the long-term increase of blood uric acid, which leads to the saturation and precipitation of uric acid to form urate crystals, which are deposited in the joint cavity. Of course, not all high blood uric acid will cause gout, as mentioned earlier, two conditions, the first is the long-term elevation of urine orange sakurate crystal deposition in the joint cavity, and the second is the activity of urate crystals to scratch the synovium. Of course, there are also some gout patients who do not have arthritis as the first symptom, and urate crystal deposition is caused by kidney damage.

The most common causes of gout (high blood uric acid) in patients are as follows:

1. Genetic factors: gout is a common metabolic disease, and family members have a certain genetic predisposition;

2. Dietary habits: gout, as a metabolic disease, is related to poor diet, early metabolism and lifestyle habits of patients. Most patients like to eat too much high-purine foods such as animal offal and seafood, and love beer and high-sugar drinks for a few minutes.

3. Other diseases: gout is mostly associated with long-term smoking, taking diuretics and other drugs, or chronic diseases such as diabetes, high blood, obesity and high blood lipids. Gout attacks occur when patients with hyperuricemia are affected by factors such as excessive exercise, trauma, low water intake, or even cold (more commonly after consuming more high-purine foods).

Therefore, whenever there is an acute attack of gout, it is necessary to analyze the specific cause and carry out targeted treatment. Void Sparrow.

1) Endogenous uric acid is generated by the catabolism of proteins in human cells and other purine compounds through the action of some enzymes.

2) Purine compounds, nucleic acids and nuclear deficiency sharp proteins contained in food, after digestion and absorption, are formed by the action of some enzymes to produce exogenous uric acid.

What is gout? Essentially, gout is sudden, acute joint swelling and pain caused by hyperuricemia. Long-term hyperuricemia leads to the deposition of uric acid crystals in the joint, and over time, more and more uric acid crystals in the joint are accumulated; In the case of certain triggers, it leads to gout attacks, redness, swelling, heat and pain in a single joint.

The treasure book of traditional Chinese medicine says: Qi is bloody, and blood is self-extinguishing. Therefore, in the treatment of gout, it should be mainly based on nourishing qi, blood circulation and strengthening the kidneys, so that the qi and blood are smooth, and uric acid will not accumulate.

Gout prevention diet.

1. Quit eating high-purine foods: animal offal (liver, intestines, kidneys, brain), seafood (abalone, crab, lobster, salmon, sardines, tuna, carp, sea bass, trout, cod), shell food, meat (beef, sheep, duck, goose, pigeon), soybean food, lentils, spinach, cauliflower, asparagus, mushrooms, soup, oatmeal.

2. Quit eating high-cholesterol foods: animal offal (liver, intestines, kidneys, brain), fatty meat, squid, fish, cuttlefish.

3. Quit alcohol: Do not drink alcohol, especially beer and Shaoxing wine.

Once the blood alcohol concentration is as high as 200mg dL, the lactic acid in the blood will increase with the oxidation process of ethanol, which will block the excretion of uric acid in the kidneys, resulting in an increase in uric acid in the blood.

4. Quit acidic foods, such as coffee, fried foods, and high-fat foods. The acid-alkaline imbalance will affect the body's functions and increase the burden on the liver and kidneys.

Dietary remedies for gout patients.

Barley porridge: Take an appropriate amount of barley and white rice, the ratio of the two is about three to one, and soak the barley in water first.

For four or five hours, soak the rice for 30 minutes, then mix the two and boil them together with water to make porridge.

Winter melon soup: take 300 grams of winter melon (without skin) and red dates.

Five or six, a little shredded ginger. Stir-fry the ginger shreds with oil until fragrant, then put them in a pot together with the sliced winter melon and red dates, add water and an appropriate amount of seasonings to cook into a soup.

It is generally believed that primary gout is mostly hereditary, but only 10% to 20% of people have a family history of gout. Hyperproduction of uric acid accounts for 10% of primary hyperuricemia**. The main reasons for this are purine metabolizing enzyme deficiency, hypoxanthine guanine phosphoribosyltransferase deficiency, and phosphoribopyrophosphate synthetase hyperactivity.

Decreased primary renal uric acid excretion accounts for about 90% of primary hyperuricemia, and the specific pathogenesis is unclear and may be polygenic genetic disorders, but renal organic disease should be excluded. Secondary gout can be caused by a variety of causes, including kidney disease, blood disorders, and medications. Most of the gouts we talk about on a daily basis are primary gout.

Gout is due to high uric acid, which has a lot to do with eating habits and water intake. Avoid foods that are high in purines. Drinking plenty of water can help.

Eating high-purine foods, drinking alcohol, and eating seafood can all lead to purine metabolism disorders.

The cause of gout is related to diet: gout is caused by ingested foods that are too high in purines, which leads to high levels of uric acid in the body. 2.

The causes of gout are occupation-related: many sedentary office people are more likely to get gout, and office workers have long-term irregular diet or lack of moderate exercise and gout according to the law. 3. Causes of goutBad lifestyle habits:

Common triggers include binge eating, alcoholism, infection, trauma, surgery, and emotional agitation. These unhealthy lifestyle habits are the direct cause of gout. 4. Causes of gout: hyperlipidemia:

About 75% and 84% of patients with gout have hypertriglyceridemia, and some have hypercholesterolemia. In order to reduce the condition, gout patients should lose weight, meet the physiological weight standard, properly control their diet, reduce hyperlipidemia, and achieve the purpose of gout prevention.

Gout is an acute and chronic inflammation and tissue damage caused by the deposition of monosodium urate in the bones and joints, kidneys and subcutaneous parts, which is directly related to hyperuricemia caused by purine metabolism disorders or decreased uric acid excretion, and belongs to the category of metabolic rheumatism. Gout is divided into two main categories: primary and secondary.

Primary gout is caused by both genetic and environmental factors. Most of them have impaired uric acid excretion, and a few have increased uric acid production, which has a certain familial predisposition. Except for a very small number of congenital purine metabolism enzyme deficiency, the vast majority of ** is unknown, and it is longer than obesity, glucose and lipid metabolism disorders, hypertension, arteriosclerosis and coronary heart disease.

Secondary gout is mainly caused by decreased uric acid excretion due to kidney disease, increased uric acid production caused by myeloproliferative diseases and radiotherapy, and inhibition of uric acid excretion by certain drugs.

The doctor of Guiyang Gout Hospital told everyone that gout is caused by abnormal purine metabolism in the human body, which causes the concentration of uric acid to rise excessively in the blood, and uric acid cannot be effectively excreted, causing systemic immunometabolic diseases. The details are as follows:

1. Mainly caused by overeating, intake of more high-protein, high-purine foods, exceeding the body's metabolic capacity;

2. Intake of more seafood, beer, meat, eggs, etc., exceeds the body's ability to metabolize protein and purines, causing an increase in blood uric acid concentration, and its excretion ability in the kidneys decreases, which can not be effectively excreted and causes uric acid nodules, which are deposited in the organs and tissues of the whole body, and cause pain, swelling and dysfunction throughout the body.

Therefore, gout is an immunometabolic disease, usually caused by poor lifestyle habits.

Gout should be carried out from several aspects**: 1. Generally**, you can avoid eating animal offal, seafood, beer, and eat less spinach, cauliflower, lentils, etc. through a low-purine diet. Drink plenty of water, the daily urine output should reach 2000-3000ml, you can use baking soda to alkalize the urine, and keep the pH value of the urine in between.

2. The use of drugs to promote the synthesis of uric acid and the excretion of uric acid, allopurinol is the first choice to promote the synthesis of uric acid, and the drug to promote the excretion of uric acid is benzbromarone. There are others**, if gout pain can be relieved by anti-inflammatory and analgesic drugs, you can also use traditional Chinese medicine or Chinese patent medicine**. Many elderly people are prone to gout, and there are many reasons for gout, first of all, it may be due to the lack of attention to diet and unhealthy daily life.

And once gout develops, the joints in the body will feel stiff and start to feel pain. In general, what do we do when we have gout?

1. How to ** gout.

1. Carry out activities.

When gout occurs, although the joints will feel painful, you need to move your joints more, exercise and stretch the joints to reduce the uric acid deposition in the joints and remove the uric acid precipitation in the body. Daily exercise is also necessary for patients suffering from gout, and it is not possible to give up exercising because of the feeling of pain, but it will allow more uric acid to precipitate in the body.

2. Adjust your diet.

Patients with gout often have gout due to improper diet. In an alkaline environment, the accumulation of uric acid is more soluble. Therefore, you should eat more fruits and vegetables in your daily life to make the body alkaline and dissolve the uric acid crystals in the body, so that uric acid can be excreted from the body and reduce the pain of the body.

3. Massage and soak your feet.

Patients with gout can also soak their feet and massage more often. For areas suffering from gout, more massage is needed to relieve joint pain, and 30 minutes of massage in daily life can relieve the pain in the body. In addition, you can also soak your feet more, which can relieve the condition of gout.

2. How to prevent gout.

1. Eat less seafood and beer.

Eating seafood and drinking beer often makes it very delicious, but it is easy for the uric acid in the body to be too high and accumulate in the body. Therefore, it is necessary to eat less seafood and drink less beer in the daily diet to reduce the uric acid crystals in the body.

2. Drink plenty of water.

Although in many diseases, it is necessary to drink more water. However, in the case of high uric acid, it is also necessary to drink more water to reduce the uric acid content in the body and reduce the crystallization of uric acid in the body, so that the gout situation can be relieved.

If you want to lower high uric acid, you only need to supplement an enzyme.

Why can't your uric acid go down?

Repeatedly rising, this is because you lack an enzyme in your body, uric acid is the product of purine metabolism in your body, if the human body lacks this enzyme, it will lead to a decrease in the ability to decompose uric acid, uric acid excretion will produce hyperuricemia, causing the deposition of urate crystals, and eventually, it will lead to gout attacks.

Now there is a technology that can supplement this enzyme, so as to promote blood circulation, regulate metabolism, and reduce uric acid.