What are the causes of elevated rheumatoid factor?

Women with weak constitution and poor immunity. These women are very susceptible to the invasion of bacteria and viruses, which are the most important agents of some rheumatic diseases, so they have a much greater chance of developing rheumatism than normal female friends.

Stressed, overworked women. Modern women "go to the hall and go down to the kitchen", engage in housework at home, and work hard outside the home, women face huge mental pressure, lack of exercise, and insufficient protection of joints, which also makes the prevalence of rheumatism continue to increase.

Females during childbearing and menopause. Pregnancy, lactation and menopause occur dramatically in women's body functions and sex hormone levels, and the body's immune function is reduced or even disordered, and related rheumatic diseases are prone to occur.

Rheumatoid arthritis is a type of rheumatism that is mainly caused by prolonged exposure to cool water or wind. Internal rheumatic activity usually lasts for 3 to 6 months, and dysplasia is pain in the joints of the body, sometimes in the shoulder, sometimes in the elbow, and sometimes in the upper extremities.

Suggestions: If you have internal rheumatoid arthritis, you should minimize the activity of the affected joint and help the affected area recover. Fixing the joint with a bracket avoids tenderness and inflammation.

The main causes are synovial lining cell proliferation, interstitial massive inflammatory cell infiltration, as well as the regeneration of microvessels, the formation of vascular pannus, and the destruction of cartilage and bone tissue.

Rheumatoid factor is mostly IgM antibodies that bind to the Fc segment of anti-IgC, which bind primarily to the immune complex rather than monomeric Igc, and promote the clearance of the immune complex in the blood and the deposition of the immune complex in tissues through this mode of action of the immune complex. Rheumatoid factor can exacerbate the deposition of immune complexes in the glomeruli, but the properties of antigens and primary antibodies determine the ability of complexes to be deposited in the kidneys.

Rheumatoid factor is a commonly used clinical indicator, and high values are related to the following conditions:

1. Rheumatoid arthritis.

2. Viral and bacterial infections will cause an increase in rheumatoid factor.

3. Some congenital diseases can also be elevated to a certain extent.

Elevated rheumatoid factor can indicate rheumatoid arthritis, but it is not a specific indicator, and only the elevated rheumatoid factor cannot be diagnosed as rheumatoid arthritis.

Causes of elevated rheumatoid factor include: bacterial factors; genetic factors; Viral factors: Rheumatoid factor is ubiquitous in the human body and has certain physiological effects:

It can regulate the body's immune response; Activates complement and accelerates the clearance of microbial infections; Removes immune complexes, protecting the body from damage from circulatory complexes. Rheumatoid factor is said to be positive only when the amount of rheumatoid factor exceeds a certain titer.

Before leaving, I am afraid that I will return late.

There are many diseases that cause elevated rheumatoid factor, and RF positivity can also appear in other connective tissue diseases, other chronic inflammation and malignant tumors, such as rheumatic fever, systemic lupus erythematosus, dermatomyositis, psoriasis, sarcoidosis, chronic hepatitis, liver cirrhosis, tuberculosis, chronic bronchitis, subacute bacterial endocarditis, syphilis, leprosy, silicosis, bladder tumors, leukemia, etc.; The positive rate of rheumatoid factor in the normal population is about 5%, and the positive rate in the elderly can reach about 20%; Therefore, the diagnosis should be made in a clinical setting. It can be repeated in 1-2 months.

The internal causes of rheumatism are mainly the weakness of righteous qi and the dysfunction of the internal organs, which leads to the entry of external evils. The lack of righteousness is mostly related to physical weakness and loss of work and rest, so it is recommended that you should be better in time. Wishing you good health.