Is cancer hereditary? Can hereditary cancers be inherited?

Cancer is a terrible disease, in addition to cancer caused by abnormal cell function, there are also some people who have genes inherited from cancer, that is, the family cancer gene will be passed on to the next generationSo which cancers are hereditary.

1.Liver cancer – children are targeted for primary prevention

If the parents are diagnosed with liver cancer, the children can be the target of primary prevention, because the vertical transmission of hepatitis B virus tends to cause familial aggregation of liver cancer. In particular, mothers who carry the hepatitis B virus have a higher risk of developing liver cancer in their offspring. If there is a liver cancer patient in the family, the children should have a comprehensive liver examination regardless of whether they are in good health, such as liver function tests, B-ultrasound, etc.

2.Breast cancer - daughter risk 2 3 times higher

There is a clear genetic predisposition to breast cancer, especially between first-degree relatives. In general, mothers are 2 or 3 times more likely to develop breast cancer than daughters who have breast cancer.

3.Nasopharyngeal carcinoma – there is a clear familial genetic predisposition

The incidence of nasopharyngeal carcinoma has obvious racial susceptibility, regional clustering and familial tendencies.

4.Stomach cancer – has a lot to do with genetics

The appearance of gastric cancer has a lot to do with heredity, and there is an obvious phenomenon of family clustering. If at least two people in a family or two have the disease, and one of them is younger than 50 years old, and all patients are diffuse, it may be hereditary stomach cancer.

5.Bowel cancer – 20% to 30% of patients with bowel cancer have a family history

20%-30% of colorectal cancer patients have a family history of various cancers. If there is an immediate family member with familial intestinal polyposis, the family must go to the hospital for a check-up.

6. Thyroid cancer - more than 94% of first-degree relatives are hereditary

Clinically, it has been found that if there are 3 or more first-degree relatives (e.g., parents, children, and siblings) in the family, the probability of hereditary disease in the family is more than 94%. Therefore, if there are 2-3 relatives in the family who have had thyroid cancer, it is recommended to have early prevention and genetic screening.

Most patients have delayed their time to seek medical attention, that is, by the time the patient goes to the medical clinic to seek**, the cancer tissue has often advanced to the third or terminal stage. How**?

1. The first diagnosis and treatment of cancer is very important: the first mistake may affect the follow-up.

The timing and manner of the first time for cancer patients is crucial, and if the first time is missed, it may affect the follow-up. And the first time** doesn't just refer to the first surgery, or the first radiation or chemotherapy. First treatment refers to the overall strategy after the diagnosis of cancer, including surgery, radiotherapy, chemotherapy and other individualized integration**.

2. The selection of the first diagnosis and treatment is very important to the hospital: the surgical industry has the advantage of specialty

Unlike other diseases, this is a multidisciplinary process, covering multiple related disciplines, involving surgery, radiotherapy, chemotherapy, immunology, targeting and other methods.

Summary:If there is cancer in the family or there are cancer patients in the relatives, their descendants must have a physical examination in time and detect it early.

The vast majority of cancers are not inherited, and only a few tumors are genetically predisposed. For example, if there is a family history of breast cancer, there is a certain genetic predisposition between grandma, mother and daughter, and there is also a disease called familial multiple colon polyp history, so most of them have familial, familial multiple colon polyps This disease, more than 70 will become malignant, so since there is a familial nature, there is a familial cluster, so it has a certain genetic tendency. For example, tumors that are definitely genetically predisposed, such as multiple neurofibromas, multiple lipomas, retinoblastomas, Wilms tumors, familial breast cancer, etc.

A family history of cancer may be a risk factor for high morbidity in cancer patients.

Second, the presence of susceptibility genes in inherited genes will increase the risk of cancer.

There may be some defects in the genes that his parents have passed on to him, or there may be some predisposing genes. These people are very sensitive to or lack resistance to some carcinogens or factors, and when exposed to these substances, they are more likely to develop cancer. Therefore, this inherited factor is called genetic predisposition.

Many patients have genetic defects and are exposed to external carcinogenic factors, which leads to the occurrence of cancer. Of course, if there is no problem with the inherited genes, he may be exposed to some carcinogenic factors, and he is not prone to cancer, which can understand why some people smoke and develop lung cancer, while some people smoke for a long time without lung cancer.

3. Genetic predisposition does not mean that it must cause cancer.

Precancerous changes occur when up to 10 or more gene mutations are in a key gene before a cell becomes cancerous. If there is only a single inherited gene mutation, it does not necessarily cause cancer. However, cancer prevention should be strengthened in normal times.

Therefore, congenital genetic mutations can only make the offspring have a genetic predisposition, and the key is that the acquired environment is the biggest cause of cancer. If you want to keep your body away from cancer, you must avoid all environmental carcinogenic factors, which is the key to preventing cancer.

First of all, it is important to point out that cancer is not 100% heritable, and not all cancers will be passed on to the next generation. Different types of cancer have different genetic risks and therefore cannot be generalized.

For the purposes of current research, the following cancers have some genetic risk:

Breast cancer: Studies have shown that breast cancer has a certain family hereditary nature, especially hereditary breast cancer syndromes (BRCA1 and BRCA2). This genetic risk may increase the patient's risk of developing breast cancer.

Thyroid cancer: Although thyroid cancer is relatively heritable, there is still a certain familial genetic tendency. Some family studies have shown that the risk of thyroid cancer is related to genetic factors.

Lung cancer: Lung cancer also runs in families, especially smoking-related lung cancer. Studies have shown that smokers may have an increased risk of lung cancer, as well as their relatives.

Colorectal cancer: There is also a high genetic risk for colorectal cancer, especially some familial colorectal cancer syndromes. This genetic risk may increase the patient's risk of colorectal cancer.

It is important to note that although cancer is not 100% hereditary, genetic factors may increase a patient's risk of developing cancer. Therefore, the key to cancer prevention is to improve a healthy lifestyle, including a healthy diet, moderate exercise, weight control, smoking cessation, etc. In addition, vaccinations and regular medical checkups are also important measures to prevent cancer.

In addition to genetic factors, environmental factors can also play a role in the occurrence of cancer. For example, living in highly polluted areas, being exposed to harmful chemicals, etc., can increase the risk of cancer. Therefore, environmental factors should also be one of the important considerations for cancer prevention.

In conclusion, the heritability of cancer is not 100% per 100 per 100 per cent, and different types of cancer have different genetic risks. The key to cancer prevention is to improve a healthy lifestyle, including eating a healthy diet, exercising moderately, controlling weight, quitting smoking, etc., while being aware of the influence of environmental factors. For cancers that run in families, more attention should be paid to preventive measures to reduce the risk of cancer.

1.Hereditary breast cancer: Some breast cancer patients carry mutations in genes such as BRCA1 and BRCA2, which can be passed on to their children.

2.Hereditary ovarian cancer: Mutations in the BRCA1 and BRCA2 genes have also been associated with hereditary ovarian cancer.

5.Hereditary melanoma: People who carry a mutation in the CDKN2A gene may be at risk for hereditary melanoma.

6.Hereditary thyroid cancer: People with a mutation in the RET gene may inherit thyroid cancer.

Note that the occurrence of genetic cancers depends not only on the gene mutation itself, but also on interactions with other environmental and lifestyle factors. If someone in your family has one of the above types of genetic cancer, it is advisable to consult a genetic counselor or geneticist for genetic counseling and genetic testing to understand your personal risk and take appropriate precautions.

Not necessarily. The occurrence of carcinoma is the result of the joint action of internal and external factors, the internal causes are mainly genetic and immune function status, in tumorigenesis, internal factors are not dominant, and the real tumors that are directly related to heredity are only a small number of uncommon tumors.

The cancer most closely related to heredity is retinoblastoma in children, and half of the brothers and sisters of such patients are retinoblastoma, breast cancer, stomach cancer, and esophageal cancer, which are also related to heredity.

The role of genetic factors in most tumorigenesis is to increase the body's tendency to develop tumors and susceptibility to blind cancer factors, that is, the so-called genetic predisposition, mainly including chromosomal instability, genetic instability, etc., in short, cancer and heredity have a certain relationship, but not the main factor.

Breast cancer: Some breast cancers are caused by genetic mutations, such as those in the BRCA1 and BRCA2 genes. These genetic mutations can be passed on to their children, increasing their risk of breast cancer.

Ovarian cancer: Mutations in the BRCA1 and BRCA2 genes are also associated with ovarian cancer, so these gene mutations can also be passed on to the next generation, increasing their risk of ovarian cancer.

Colorectal cancer: Colorectal cancer can be hereditary, and about 5% of colorectal cancers are caused by genetic mutations, such as Lynch syndrome.

Thyroid cancer: Thyroid cancer can be hereditary, with about 5-10% of thyroid cancers caused by genetic mutations, such as multiple endocrine neoplasia types I and II.

It's important to note that even if you carry these gene mutations, you don't necessarily get cancer. However, these genetic mutations can increase the risk of cancer. If you have more than one member of your family with these cancers, or if you already have these cancers yourself, you should consult a doctor and consider genetic testing and screening to help identify and prevent cancer.