What causes Down syndrome? Is Down syndrome really that scary?

Down syndrome is a congenital disease, so pregnant women usually try to be screened in advance when they are pregnant, in order to prevent themselves from giving birth to a child with Down syndrome. Down syndrome refers to the congenital malformation of the child, and the probability of the disease is quite high, so it is very scary, if a child with Down syndrome is born, it is a pain for both parents and children. The onset of Down syndrome is usually due to the advanced maternal age or the damage to the embryo at an early stage, which may also be affected by genetics.

Down syndrome is indeed a very terrible disease, because the patient has an extra 21 sets of chromosomes in the body, which is indeed more common in humans, and it is a chromosomal disease. After the child with Down syndrome is born, the muscle tension of the body is relatively low, and the child is easy to open his mouth and stick out his tongue, the head shape is flat, the distance between the two eyes will be relatively large, and the ** will be relatively loose, including the palms are broken palm lines, which are all problems with a high probability. Moreover, children with Down syndrome generally have low intelligence, congenital heart disease, abnormal overall appearance, slow development, and shorter life expectancy than normal children.

Generally, pregnant women who are over 35 years old are considered to be elderly pregnant women, and the risk of pregnant women with Down syndrome is higher than that of ordinary pregnant women. And if the embryo is affected in some way in the early stages of pregnancy, it may also induce a Down syndrome. If the family has had the experience of having a Down child before, then the chance of a pregnant woman being pregnant with a Down child is also higher.

The best way to prevent children living at the same time is to get a comprehensive screening early in pregnancy. Because this is a disease caused by chromosomal abnormalities, it is necessary to check the baby's chromosomes, there is no good way to find this disease, only to detect it early, and then see if the pregnant woman is willing to keep it. Therefore, this also fully illustrates the importance of prenatal examination, and you must not stop doing it because you save money or are too troublesome.

It may be that there is a problem with the parents' genes, ovarian malformations, and genetic factors can lead to Down syndrome. Down syndrome is indeed very scary, it will affect the child's development, it will affect the child's IQ, this disease is not good, it will affect the child for a lifetime.

There are many causes of Down syndrome, and the common pathogenic genes are complex, and children with Down syndrome can have lifelong disabilities, which is very scary.

It may be because the maternal age is too old, there is a hereditary, chromosomal disease, so it will lead to Down syndrome; Yes, Down syndrome is very scared and can cause the child to have a deformity.

Special features: dull expression, dull eyes, small eye fissures, wide eye distance, upward slanted eyes, flat face, low and flat nose bridge, small outer ears, small head and short and wide neck.

Mental retardation: This is the most prominent manifestation of Down syndrome. It usually manifests as different degrees of intellectual developmental disability, and it becomes more and more obvious with age.

Language disorders: language development is delayed, and most of them have pronunciation defects, slurred speech, stuttering, and low voice.

Behavioural disorders: Most of the children with Down's family are mild and like to giggle. You can imitate and perform some simple actions.

Bradykinesia: poor motor function, clumsiness, and unsteady walking.

Introduction to Down syndrome.

Down syndrome or trisomy 21, also known as congenital stupidity in China, is one of the most common serious birth defects. The clinical manifestations are: the patient's face is special, the corners of the eyes are upturned, the bridge of the nose is flattened, the tongue is often sticking out, muscle weakness and penetrating the hands.

The vast majority of patients have severe intellectual disability accompanied by abnormalities of various organs, such as congenital heart disease, leukemia, gastrointestinal malformations, etc. The disease occurs almost everywhere in the world, and there are few racial differences. According to statistics, the incidence of chromosomal abnormalities in neonates is 5-6 1000, and the incidence of Down syndrome is about 1 750, and the vast majority of patients occur randomly, but the incidence increases with the age of the mother, and the birth rate of the child can be as high as 1 350 when the mother is over 35 years old.

In the past, the only way to diagnose these diseases was to do amniotic fluid or chorionic villus tests, but these methods were limited to some high-risk pregnant women because they were time-consuming, costly, and troublesome to operate. In addition, about 80% of fetal chromosomal diseases occur in ordinary pregnant women, because the absolute value of fertility in this group exceeds that of high-risk groups, so prenatal diagnosis from the perspective of eugenics cannot be ignored. The actual situation is that the prenatal diagnosis department for this group of people has so far been unable to bear it, and eventually this group of people has become a blind spot for eugenics.

In 1988, the emergence of serum marker screening methods fundamentally changed the passive situation of prenatal prevention of the above-mentioned diseases.

Down syndrome is caused by chromosomal abnormalities, which means that children with Down syndrome have one more chromosome 21 than healthy children. There are several reasons for its occurrence: the first is genetic factors, that is, one of the parents of the child is a carrier of this 21-trisomy and contains this disease-causing gene, but it does not develop the disease, but it becomes the disease in the child.

The second is a high-risk pregnancy. Even if the mother's pregnancy age is relatively old, more than 35 years old, it will also lead to an increase in the chance of chromosomal abnormalities. In addition, the mother takes some special drugs orally during pregnancy, or is exposed to special radioactive substances or some chemical agents, which can also lead to the occurrence of chromosomal abnormalities.