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Patients with advanced Parkinson's disease mainly have the following symptoms: 1The phenomenon of the end of the agent, the phenomenon of switching, the phenomenon of morning stiffness.
2.dyskinesia. Manifests as involuntary or chorea-like movements or abnormalities in muscle tone of the trunk and limbs.
3.Psychiatric symptoms: Psychiatric symptoms occur in about 30% of people with Parkinson's disease. It may be a nightmare at first, followed by disorientation, hallucinations, and delusions. There will also be varying degrees of depression and anxiety symptoms.
4.Sleep disturbances and cognitive dysfunction.
5.In severe cases, patients will be bedridden and unable to take care of themselves. At this time, it is important to take good care to prevent lung infections, urinary tract infections and pressure sores.
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Parkinson's disease cannot be used because Parkinson's disease is a degenerative disease of the nervous system in the elderly, which is one of the physiological signals that represent the aging process of human beings. After the onset of Parkinson's disease, there will be autonomic dysfunction, abnormal muscle tone of the limbs, and with the development of the disease, the brain dysfunction will gradually worsen, and the patient's substantia nigra dopamine neurons will irreversibly die, so this disease can not **.
Although it cannot be **, it can be effectively relieved by drugs and other methods, so as to improve the quality of life. Patients with Parkinson's disease need to take anti-Parkinson's drugs for life, and if the medication is stopped, symptoms may recur or even worsen.
Patients with early Parkinson's disease should be prompted**, which has a great impact on improving the quality of life of patients. In the early stage of Parkinson's disease, compound levodopa can be used, which can be converted into dopamine after entering the brain to supplement the deficiency of dopamine in the striatum nigra, so that dopamine and cholinergic neurotransmitter acetylcholine can be balanced, and the purpose of replacing ** can be improved, thereby improving Parkinson's disease. In the middle stage of Parkinson's disease, the focus is on improving motor complications, and the combination of drugs and surgery can be used, and traditional Chinese medicine can be carried out at the same time to delay the progression of the disease.
In the advanced stage of Parkinson's disease, the main focus is to actively prevent complications of the disease and prolong the life of patients through effective care.
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Parkinson's disease, this disease is a chronic progressive disease, although some drugs can improve its progression, but so far, there is no drug that can completely ** Parkinson's disease, so Parkinson's disease, generally speaking, after 3 to 5 years, will gradually worsen, advanced Parkinson's disease, what are the clinical manifestations?
Then there are mainly the following aspects::
First, there will be mental decline, many patients with Parkinson's disease, after the advanced stage, his memory, including the cognition of higher cortical functions, including finding the way home, will have functional decline, so this kind of higher cortical dysfunction is often called dementia caused by Parkinson's disease, or dementia caused by PD.
Second, there will be emotional changes, many Parkinson's disease patients in the later stage, he will be apathetic, depressed, slow to react, and then poor self-control, and some patients will lack self-esteem, pessimistic and misanthropy, and even some patients, sensitive and suspicious, full of suspicion, anxiety, fear, and easy to accumulate heat and other bad emotions, a small number of paroxysmal sexual impulses, aggressive behavior. In addition, in the later stages of Parkinson's disease, due to nutritional dysfunction, including eating dysfunction, he may be emaciated.
In addition, patients with Parkinson's disease will also have a low sense of smell, and patients with Parkinson's disease are prone to salivation due to his swallowing dysfunction, that is, he keeps drooling, and this drooling is not due to the increased saliva secretion, but due to the dysfunction of saliva swallowing.
So his saliva was all coming out of his mouth, so he kept needing a towel to wipe his sleepy rent. In addition, patients with Parkinson's disease, in the advanced stage, will have severe motor dysfunction. So basically, it is slow movement, and even some patients are unable to move and stay in bed for a long time, at this time we need to strengthen nursing to prevent the occurrence of bedsores and lung infections.
Of course, in the later stages of Parkinson's disease, sleep dysfunction will also occur, so because you can't sleep at night and your muscles are stiff, you will feel sleepy during the day.
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What is the condition of late Parkinson's disease? Zuo felt that if Parkinson's was in the late stage of excavation, he must be relatively unable to take care of himself, and he needed the help of others to live and scatter hail. So when we have early symptoms, it's your stones**.
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In the late stages of Parkinson's, the patient is confined to bed because the patient is getting weaker and weaker, and the limbs become stiff.
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The late stage of Parkinson's syndrome is generally manifested as dizziness and hand trembling, which makes it a little inconvenient to move.
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The symptoms of late Parkinson's disease are inability to control the hands and feet, trembling, and then mental retardation and decreased motor ability until they are unable to move independently.
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Patients with advanced Parkinson's disease will have generalized muscle rigidity, which can lead to dysphagia and difficulty breathing. In addition to the manuscript of the spring stool, the patient will also show difficulty turning over and sitting up. Patients with severe conditions will also have pneumonia, malnutrition, and bedsores.
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Parkinson's disease is a common neurodegenerative disease in middle-aged and elderly people, with the development of the disease, there may be unsteady walking, easy to fall, easy to fracture, difficulty in eating and drinking, difficulty in turning over, complete loss of self-living ability, sometimes there will be involuntary dancing of limbs or trunk, due to decreased immunity and suffering from upper respiratory tract infection, lung infection, urinary system infection and other infectious diseases, and it is not easy to heal, in severe cases, there will be complete loss of memory, mental decline, Emotional instability.
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1. The body is stiff, and some patients rely entirely on wheelchairs.
2. Hallucinations, similar to the symptoms of psychosis;
3. Mood changes, often anxious or depressed, or becoming timid, fearful, or short-tempered and easy to get angry;
4. Decreased intelligence, dementia, slow response, similar symptoms to Alzheimer's syndrome;
5. Loss of sense of smell, difficulty swallowing, stiffness of joints, severe lung infection, and even osteoporosis, fractures, bedsores, etc.
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In the late stage of Parkinson's disease, there will be severe abnormal posture and gait, and even long-term bed rest. It is recommended to go to the neurology department of the hospital for further treatment. so as not to delay the condition. Be careful not to choke on the booklet to avoid respiratory suffocation.
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Symptoms of late Parkinson's disease.
1. Parasomnias: This phenomenon is very common in patients with Parkinson's disease, such as rapid eye movement sleep behavior disorder, periodic leg movements, nightmares, etc. REM sleep behavior disorder refers to the relaxation of muscles during the patient's rapid staring and slow eye movement sleep, and also produces dream-related motor behavior disorders, which have a certain lethality, including self-harm and threats to surrounding people.
2. Very sleepy and sleep attacks during the day: According to relevant data, almost half of the patients will be very sleepy during the day, especially after noon, and the phenomenon of dozing off is the most. If insomnia is more severe at night, the degree of sleepiness during the day will increase.
However, there is also a distinction between this sleepiness and sleep episodes. Sleep episodes usually indicate sudden, irresistible sleep that usually lasts only a few seconds.
3. Muscle rigidity: It is one of the typical symptoms of Parkinson's disease, which is usually formed by the increased tone of agonist muscles and antagonistic muscles. Because of the increase in muscle tone, the patient also has some abnormal conditions, such as chewing, walking and other movements become less.
4. Insomnia at night: mood is affected, nocturia is more rotten, it is difficult to turn over, lower limb convulsions, dreaming, etc. are all phenomena that will lead to insomnia at night. In addition, some medications can also cause insomnia in patients.
If the patient has insomnia and Parkinson's disease, the symptoms of insomnia will gradually worsen due to the presence of various factors.
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Advanced Parkinson's disease:
1. Hyposmia: This is a late symptom of Parkinson's disease, and many patients with Parkinson's disease have a reduced or lack of sense of smell.
2. Autonomic nerve dysfunction: Generally, there will be a certain degree of neurological disorder in the later stage of Parkinson's disease, which directly affects the patient's various systems. Patients often have dyskinesia and dysphagia in the esophagus, stomach and small intestine, and esophageal spasm.
3. Gradual loss of physical motor function: It is extremely obvious in this point, and the normal motor function of patients with severe damage to Parkinson's disease in the later stage until the complete loss of motor ability, often accompanied by muscle contractures, joint rigidity and other symptoms.
4. Mental depression, mostly suicidal tendencies: Parkinson's patients will have different degrees of depression, anxiety and other diseases, which will be especially obvious in the later stage, and most of them have suicidal tendencies, short tempers, and difficult to contact.
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The symptoms of advanced Parkinson's disease are: 1. Movement disorders, such as bradykinesia, resting tremor, hypertonia, and abnormal posture; 2. Depression and anxiety are aggravated, and even patients have hallucinations after taking medicine, such as feeling that there are flies, mosquitoes, rats, bad guys, etc. 3. Autonomic dysfunction, such as obvious sweating, dyspepsia, intractable constipation, restless sleep at night, and some patients are complicated by restless leg syndrome. Precautions for home care of Parkinson's disease should be based on two points: 1. Avoid lung infection caused by late aspiration; 2. Avoid fractures caused by falling.
Therefore, nursing needs to start from these two points, such as laying carpets at home, installing guardrails at the bedside, and providing patients with simple and convenient daily necessities.
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The symptoms of Parkinson's disease in the later stages are as follows: falling, difficulty swallowing, choking on water, lung infection, inability to take care of oneself, long-term bed rest, bedsores, venous thrombosis of the lower limbs, constipation, hallucinations, severe anxiety, etc. It is mainly manifested in the following aspects:
1. Balance disorders, frozen gait, easy to fall. After a fall, fractures, head injuries, etc., will occur, which will seriously affect the quality of life of patients. Not even able to stand alone, walk, stay in bed for a long time.
2. Swallowing dysfunction, the patient has difficulty swallowing, choking on drinking water, malnutrition, emaciation, food or saliva aspiration to the lungs, lung infection, etc. 3. Some patients are bedridden after the middle and late stages, and are prone to complications such as bedsores and deep vein thrombosis of the lower limbs, long-term bed rest or wheelchair sitting, joint deformity, and contracture deformity. Fourth, the development of the disease itself and the drug ***, in the middle and late stages, there are often hallucinations, seeing things that are not actually there, and most patients with differential chain division will have mental symptoms such as anxiety and depression.
5. A small number of patients will have cognitive dysfunction, such as decreased speech function, difficulty in cooperating, slow response, decreased calculation, memory loss, drowsiness, or insomnia, and even dementia.
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The late symptoms of Parkinson's disease are motor complications, and the symptoms of walking and tremor can be significantly relieved after medication in the early stage of the disease, but with the decline of efficacy in the later stage, Parkinson's patients will first have motor complications. Symptoms such as unsteadiness, stiffness, tremors, etc. and dyskinesia syndrome, including involuntary body shaking, chorea-like forward movements, and later can also lead to urinary retention, cognitive impairment, osteoporosis, peripheral nerve damage and other corresponding complications.
Parkinson's patients have a panicked gait and are prone to falling, often due to fractures that affect the quality of life, and even combined with lung infection and urinary tract infection, which is an important cause of later death in Parkinson's patients.
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Tremor: Commonly seen in the head and limbs, especially in the fingers. As the disease progresses, the tremor gradually affects all the limbs and even the trunk.
Posture and gait: dull face, stiff expression; The head is tilted forward, the torso is tilted forward, the elbows, knees are slightly bent; The walking distance is small, it starts slowly and gets faster and faster, showing a nervous gait.
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It is very serious for Parkinson's disease to progress to an advanced stage.
On the one hand, Parkinson's disease develops to an advanced stage and presents a flexion posture, which is manifested as spinal prodroma, elbow flexion, wrist joint straightening, head tilt forward, severe mandibular area will be close to the forechest, etc., and symptoms such as inability to turn over involuntarily, difficulty swallowing, and easy choking after eating. In addition, due to the patient's long-term bed rest, it is easy to lead to complications such as lung infection, bedsores, urinary tract infection, and intestinal obstruction. In addition, patients will experience mental symptoms such as anxiety, depression, pessimism and hopelessness, loss of confidence in life, and life is very painful.
Therefore, for Parkinson's disease, it is necessary to achieve early detection, early diagnosis and early treatment, and at the same time of taking drugs, it is necessary to strengthen functional exercises to prevent serious consequences such as muscle contractures.
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Late Parkinson's symptoms.
1. Parkinson's patients cannot move freely like normal people because of motor nerve disorders. Then Parkinson's patients are prone to symptoms of hyposmia in the advanced stage: Parkinson's disease will have a loss of smell in the advanced stage, which is a common manifestation of Parkinson's symptoms in the advanced stage, and many Parkinson's disease patients have hyposmia or lack of smell.
These defects appear early and do not appear to be related to the duration of the disease. 2. Mood and intelligence changes are also symptoms of Parkinson's disease: Mood and intelligence changes are common manifestations of late Parkinson's symptoms.
People with Parkinson's disease can also have psychiatric symptoms, which manifest as symptoms of depression and dementia. Some patients have apathetic expressions, depressed mood, slow response, poor self-control, lack of self-confidence, pessimism and misanthropy, suspiciousness, stubbornness, fear, irritation, etc., which is one of the late symptoms of Parkinson's. 3. Autonomic nerve dysfunction:
Patients with Parkinson's disease reach an advanced stage, and most patients will cause some degree of neurological disorder, which directly affects the patient's various systems. 4. The symptoms of Parkinson's disease also include patients often have intractable constipation, rarely intestinal obstruction, and movement disorders of the esophagus, stomach and small intestine can cause dysphagia, esophageal spasm and gastric-esophageal reflux.
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