Which is better, Chinese medicine ultrafine powder or Chinese medicine extract?

The extraction is the so-called purification of the active ingredients, and the ultrafine powder is the fine production of the original medicinal materials, which relatively retains the original appearance of the original medicine. As for the former, the ingredients are relatively single, and the structural formula of drug resistance is easy to form, but after all, the purity of the active ingredients is high; The latter is in its original state, with complex composition, and the drug-resistant structure is not easy to produce or destroy.

The efficacy of traditional Chinese medicine itself is the result of the joint action of many aspects, and people want to know the mechanism of action, so they analyze its composition and extract appears. The extract has an effect, but it does not reach the original drug. The original drug is difficult to quantify, but the extract can be quantified.

It's actually a matter of testing. The difficulty of the modern production of traditional Chinese medicine is that it cannot be accurately quantified, while Western medicine can. Traditional Chinese medicine is vague, Western medicine is clear (the ancestor of many Western medicines is Chinese medicine, such as aspirin).

Therefore, things that cannot be solved by Western medicine, which can be solved or alleviated by Chinese medicine.

Not necessarily. For example, several of our company's products are ultra-fine powder. It has been burned like human medicine. The effect is better than the extract.

I don't know what the concept of so-called ultrafine powder is, but if traditional Chinese medicine wants to break the wall, the fineness should reach about 200-240 mesh.

In addition, the current veterinary drug sales, which manufacturer can afford the cost of producing this fineness?

So I personally think that it is still an extract at present.

Reply. #

Traditional Chinese medicine ultrafine powder is a fine powder of medicinal materials for better absorption.

The extract is the main ingredient that is effective in extracting Chinese medicine.

For example, there are other substances in astragalus powder in addition to astragalus polysaccharides.

Astragalus polysaccharides are extracts of Astragalus membranaceus.

Contains only polysaccharides.

In the early years, some people hyped up the concept of ultrafine powder of traditional Chinese medicine, but the traditional Chinese medicine was generally crushed and grinded, although it was also a fine powder state, but it did not meet the standard in the concept of ultrafine powder, and could not be called ultrafine powder in the real sense.

Traditional Chinese medicine ultrafine powder is a powder powder made by using the world's leading ultrafine grinding technology to process the cell wall of traditional Chinese medicine. 80% of Chinese herbal medicines are based on botanicals, and the active ingredients of plant medicinal materials are mostly stored in the cells, and ultrafine grinding technology (ultrafine grinding technology of traditional Chinese medicine refers to the process of using mechanical or fluid power to crush more than 3mm material particles to a particle size of less than 30um) can break the cell wall of plant medicinal materials, so that the active ingredients in the cells are fully released, thereby improving the bioavailability of medicinal materials, which is conducive to the absorption and utilization of drugs by livestock and poultry bodies, and makes a qualitative leap in the clinical effect of Chinese herbal medicine. The ultra-fine grinding technology has broken the "medicine jar" that has been used for thousands of years, and is known as a landmark revolution in the history of traditional Chinese medicine decoction pieces.

The dissolution rate of the drug is generally proportional to the specific surface area of the drug particles, and the specific surface area is inversely proportional to the particle size. The ultrafine powder has a small particle size, an increase in the specific surface area, a larger contact area with the gastrointestinal mucosa, and enhanced adhesion, which makes the drug stay in the digestive tract for a long time and makes the drug more fully absorbed, thereby improving the bioavailability of the drug.

After the cell wall is broken, the effective ingredients in the broken wall cells can all be directly absorbed by the animal, and most of the cells are complete in the general crushed granules and decoction pieces, and the particles are composed of several, dozens or even more cells, the dissolution of the effective medicinal ingredients in the cell needs to pass through several or even dozens of cell walls to enter the animal body, and then be absorbed by the animal, and a considerable part of the cell components can not pass through the cell wall into the animal body, this part can only be thrown away in vain.

The dissolution rate of the drug is generally proportional to the specific surface area of the drug particles, and the specific surface area is inversely proportional to the particle size. The ultrafine powder has a small particle size, an increase in the specific surface area, a larger contact area with the gastrointestinal mucosa, and enhanced adhesion, which makes the drug stay in the digestive tract for a long time and makes the drug more fully absorbed, thereby improving the bioavailability of the drug.

Therefore, the amount and speed of the release of the active ingredients of ultrafine powder Chinese medicine, the amount of active ingredients absorbed in a unit time will be higher than that of the traditional Chinese medicine powder obtained by the ordinary crushing method, and the types of active ingredients released will be more complete than that of the ordinary crushing method, and the onset time of the drug will be significantly shortened, the effect will be more comprehensive, and the intensity of action will be higher.

After the drug enters the animal body, it must first go through the action of beneficial bacteria in the body, due to the small particles of ultrafine powder of traditional Chinese medicine, the effect of beneficial bacteria will be faster and stronger, and the amount and concentration of products produced by the effect of bacteria will be significantly increased, which is also beneficial to the absorption of animals and improve the absorption intensity.

Due to the small particles, the adhesion of the cell fragments of traditional Chinese medicine ultrafine powder to the intestinal wall is strengthened, and the residence time of traditional Chinese medicine particles in the intestine will increase, which is conducive to drug absorption. Traditional Chinese medicine itself is a natural substance that coexists with humans, many of which have also entered the human food chain, and the vast majority of them do not have toxic and drug residues, and some can effectively reduce drug residues in livestock and poultry products, which are suitable for safe and green food production; The multi-target effect of traditional Chinese medicine makes pathogenic microorganisms not easy to produce drug resistance and resistance, and the production process of breeding enterprises does not need to change drug regimens frequently.

Concept: Many Chinese herbal medicines can be ultra-fine pulverized to become ultra-fine powder of Chinese herbal medicines. It is generally believed that its particle size is not between 1 and 75um, and the average particle size of most traditional Chinese medicine ultrafine powders is 15um.

Features: Ultra-fine grinding of medicinal materials, with the characteristics of controllable quality, saving medicinal materials, enhancing efficacy, promoting absorption, convenient blending, and easy to take.

Controllable quality: The particle size range of ultra-fine Chinese herbal medicine granules is 1-75um, and compared with traditional Chinese medicine decoction pieces and traditional Chinese medicine preparations, the pharmacodynamic material base of granules in this range will not occur obvious changes in molecular structure, and will not lead to changes in the attributes, pharmacodynamic characteristics and functional indications of traditional Chinese medicine, providing a basic guarantee for the efficacy and stability of traditional Chinese medicine.

Traditional Chinese medicine ultrafine grinding technology in the mid-to-late 90s of the 20th century, it follows the theory of traditional Chinese medicine under the premise, combined with the characteristics of traditional Chinese medicine materials, the use of modern powder technology, Chinese herbal medicines, Chinese medicine extracts and Chinese medicine preparations micronized, the technology is a very rapid development of a new technology at home and abroad in recent years, is one of the important directions of the modernization of traditional Chinese medicine.

Ultrafine grinding technology is used in medicine, food, cosmetics and ceramics and other industries, and its domestic application started late, but with the application advantages of this technology in the traditional Chinese medicine industry gradually emerging, people are paying more and more attention to it. This technology has been more and more widely used in other related industries, such as traditional Chinese medicine health care products industry, food deep processing industry, etc., and has achieved good results, becoming a huge driving force for the development of new products.

The cell diameter of Chinese herbal medicines (plants) is usually about 10-200 m, and the particle size of Chinese herbal medicine ultrafine powder can generally be crushed to a powder with a cell particle size of 48 m (300 mesh) and 25 m (500 mesh), and it can even be soluble in water for drinking. The ultra-fine powder mentioned in the national pharmacopoeia is about 200 mesh powder, and the fineness is about that the ultrafine powder of Chinese herbal medicine is much finer than this.