What causes restless legs syndrome?

1) The cause of the disease.

The cause and pathogenesis of this syndrome are not well understood, but it is believed to be related to various factors such as nerves and psychiatry, and some people speculate that it is related to the accumulation of tissue metabolites caused by blood circulation disorders in the feet based on the characteristics of the onset of the disease at rest and the relief of symptoms after exercise. It is also believed that this syndrome is more common in peripheral neuropathy caused by anemia, diabetes, alcoholism, and vitamin deficiencies, so it is speculated to be related to metabolic disorders.

Traditional Chinese medicine believes that this disease is caused by the stagnation of the skin, stagnation of the veins, or the deficiency of yin and blood, and the loss of nourishment of the meridians and skin. Its disease location is mainly in the meridians and skin, and is related to the heart, liver and kidney; Its pathology is based on false standards.

ii) Pathogenesis.

The pathogenesis of this syndrome is not well understood, but it has been speculated that it is related to the accumulation of tissue metabolites caused by impaired blood circulation in the feet. It is also believed that this syndrome is more common in anemia, diabetes, alcoholism, and vitamin deficiencies, so it is considered to be a metabolic disorder.

Restless legs syndrome refers to a syndrome in which unbearable discomfort occurs in the deep part of the calf at rest, which can be temporarily relieved by exercise and massage, also known as "restless legs syndrome". The clinical manifestation is usually extreme discomfort in both lower limbs during sleep at night, forcing the patient to constantly move the lower limbs or walk on the ground, resulting in severe sleep disturbances. So, what causes restless legs syndrome?

Let's answer it for you.

1. Genetic and endocrine factors.

Restless legs syndrome may be a genetic factor, and in some patients, 43% of relatives have similar diseases, and there is also family recessive inheritance. In addition, it may be caused by endocrine factors, which is more common in pregnant women. A retrospective diagnosis of 486 women who had recently given birth was found to be present, and 27% of pregnant women had restless legs syndrome.

2. The doctrine of ischemia.

Restless legs syndrome can also be caused by ischemia, which can also occur at rest or when working in a cold environment for long periods of time. Massaging local muscles or moving local muscles, beating local muscles, using some vasodilators can relieve symptoms, and some patients have blood flow maps of the limbs showing a decrease in blood flow, many experts believe that this disease is caused by the blood circulation disorder of local tissues, resulting in the accumulation of metabolites and causing this disease.

3. Metabolic and nutritional disorders.

The cause of this disease may also be metabolic abnormalities or nutritional disorders, some patients with high cholesterol, hypercholesterolemia, uremia, diabetes will have metabolic peripheral nerve diseases that can cause restless legs syndrome, and physical defects, anemia, iron deficiency is also related, many patients in the examination of the body, serum iron is lower than normal.

Restless legs syndrome, also known as restless legs syndrome or Willis-ekbom disease, is a neurosensorimotor disorder that primarily affects the legs. Specifically, patients experience indescribable discomfort in the lower extremities at rest, forcing a strong desire to move their legs, and symptoms are often worse at night.

May be genetic; Secondary restless legs syndrome is often associated with a variety of disorders or drug use.

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Primary restless legs syndrome.

May be related to genetics, abnormal dopamine function in the brain.

Secondary restless legs syndrome.

Many disorders predispose to restless legs syndrome, such as chronic renal failure.

Polyneuritis, rheumatoid arthritis.

Parkinson's disease. Sjögren's syndrome.

Iron deficiency anemia.

Folic acid. and vitamin B12 deficiency, etc., in addition, hemodialysis.

A history of use of specific drugs can also lead to the disease.

What are the triggers for restless legs syndrome?

Poor living conditions and malnutrition.

Decreased immunity and pregnancy can induce restless legs syndrome.

The exact form of restless legs syndrome is unclear and may be related to iron deficiency.

The disease is a sleep disorder, generally patients present with indescribable paresthesias in both lower limbs during sleep or at rest, including worm wriggling, ant walking and swelling, which often forces patients to have a strong desire to move the lower limbs, and the symptoms may be temporarily relieved after the lower limbs are moved, and the symptoms can appear again after stopping activities, and in severe cases, it may affect the patient's sleep time and sleep quality. In mild cases, no special ** is generally required, and symptomatic ** can be carried out when the symptoms are severe, iron supplementation may improve the patient's symptoms, and oral levodopa or oral clonazepam may improve the symptoms, which generally occur in middle-aged and elderly people, and can occur at any age. Restless legs syndrome may have a certain relationship with genetic factors, some patients have a family history, autosomal dominant inheritance, lack of iron in the body, iron supplementation can also be **restless legs syndrome, iron deficiency may be a factor of restless legs syndrome, central nervous system, dopamine neuronal damage, too much endogenous opioid release, may cause restless legs syndrome.

Secondary factors such as Parkinsonism, multiple sclerosis, multiple system atrophy, iron deficiency anemia, spinocerebellar ataxia, cerebral infarction, cerebral thrombosis, uremia, and liver dysfunction may induce restless legs syndrome, which can also be caused by anxiety, depression, and irritability.

Restless legs syndrome is characterized by indescribable paresthesias and discomfort in the lower limbs at rest, a strong desire to move the legs, and patients are constantly forced to knock on the lower limbs to relieve pain, often aggravated at night rest. The ** of this disease divides restless legs syndrome into two types: primary and secondary, according to whether there is a primary disease. Secondary restless leg syndrome is mostly secondary to some diseases, according to the literature, 45% of patients are secondary to spinocerebellar ataxia type 3, perone-muscar-muscular atrophy is 37%, iron deficiency anemia is 24%, uremia is accounted for in pregnant women, after surgery, tremor paralysis accounts for 1%, and diabetes mellitus accounts for 1%.

Primary restless legs syndrome, the cause of which is unknown, is thought to be related to genetics and abnormal dopamine function in the brain.

At present, restless legs syndrome is considered to be a central nervous system disorder, and the specifics have not been fully clarified. It is mainly divided into primary and secondary.

1.Primary It is thought that it may be related to genetics, abnormal dopamine function in the brain.

2.Secondary Many diseases are predisposed to be associated with restless legs syndrome, such as patients with advanced renal failure, hemodialysis patients, polyneuritis, rheumatoid arthritis, Parkinson's disease, Sjögren's syndrome, pregnant women, anemia, and iron deficiency. Some studies suggest that 65 patients have reduced cerebrospinal fluid iron levels and that symptoms improve with oral or injectable iron.

Primary restless legs syndrome.

May be related to genetics, abnormal dopamine function in the brain.

Secondary restless legs syndrome.

Many disorders predispose to restless legs syndrome, such as chronic renal failure.

Polyneuritis, rheumatoid arthritis.

Parkinson's disease. Sjögren's syndrome.

Iron deficiency anemia.

Folic acid. and vitamin B12 deficiency, etc., in addition, hemodialysis.

A history of use of specific drugs can also lead to the disease.

What are the triggers for restless legs syndrome?

Poor living conditions and malnutrition.

Decreased immunity and pregnancy can induce restless legs syndrome.

The cause of restless legs syndrome has not been elucidated, and it is currently considered to be a disease of the central system. It is mainly divided into primary and secondary. Primary restless legs syndrome is thought to be related to genetic, abnormal dopamine function in the brain.

Secondary restless legs syndrome, many disorders tend to be comorbid. Such as patients with advanced kidney failure, renal dialysis patients, polyneuritis, rheumatoid arthritis, Parkinson's disease, Sjogren's syndrome, pregnant women, anemia, iron deficiency, etc. **Dopaminergic drugs such as pramipexole are preferred, but antiepileptic drugs such as gabapentin, carbamazepine, pregabalin, etc. may also be used.

Restless leg cleft syndrome is a disease of the central nervous system, the cause of which is not well known so far. It can be a primary or secondary two-sock rolling type, and primary restless legs syndrome may be related to genetic factors. Secondary restless legs syndrome can be seen in many diseases, such as rheumatic immune diseases that invade the central nervous system, degenerative diseases of the brain, diabetic central nervous system disease, etc.

Iron deficiency anemia can also cause symptoms of restless legs syndrome. It is recommended that you do further testing to see what kind of cause it belongs to, and then do it to target the good and bad behavior**.

In many cases, it may be excessive exercise, or it may be a herniated lumbar disc, and it is recommended to go to the hospital.

State**. Symptoms of medical attention** prognosis daily.

The cause of primary restless legs syndrome is often unclear and may be genetic; Secondary restless legs syndrome is often associated with a variety of disorders or drug use.

What are the causes of restless legs syndrome?

Primary bending stool restless legs syndrome.

May be related to genetics, abnormal dopamine function in the brain.

Secondary restless legs syndrome.

Many disorders predispose to the syndrome of restless legs, such as chronic renal failure.

Polyneuritis, rheumatoid arthritis.

Parkinson's disease. Sjögren's syndrome.

Iron deficiency anemia.

Folic acid. and vitamin B12 deficiency, etc., in addition, hemodialysis.

A history of use of specific drugs can also lead to the disease.

What is the cause of restless leg syndrome Restless leg syndrome and Bi Zheng are leg discomfort at rest, and the main causes of Lao Qin are as follows: 1. Genetics, excluding the family history of patients with Lunning leg syndrome. 2. Malnutrition, such as lack of folic acid and vitamin B12 deficiency, is more common in patients with digestive diseases and picky eaters.

The pathogenesis of restless legs syndrome is not well understood, and may be related to abnormalities in the dopamine system. Kidney failure, iron deficiency, antidopaminer, and anti-anxiety drugs can all cause secondary restless legs. Restless legs syndrome can occur in people of all ages, but it is more common in older people.

The main manifestation is that whenever the patient falls asleep at night, there will be an indescribable soreness, numbness, swelling, sleepiness, burning, worming, itching and other uncomfortable feelings in the deep muscles, which makes it difficult to fall asleep. Symptoms may be temporarily relieved and disappear after massage, thrashing, swinging limbs, or getting out of bed and walking around. Restless legs syndrome refers to an indescribable sensation in both lower limbs when the patient is about to fall asleep at night, forcing the patient to walk on the ground to relieve the symptoms, and the patient may present with discomfort in the lower limbs or a burning sensation in the car.

The reason for its formation is not very clear, but it can be alleviated in the following ways: 1. It is recommended to give the patient some drugs, such as oral methylcobalamin and vitamin B1 to nourish the nerves**. Second, patients can be given anti-anxiety and antidepressant drugs, such as sertraline hydrochloride, which also has a certain relief for restless legs syndrome.

3. Use traditional Chinese medicine to alleviate symptoms, such as oral traditional Chinese medicine to promote blood circulation and eliminate blood stasis, such as Shuluo Ning leg soup or acupuncture and moxibustion to improve symptoms. The above is a closed calendar advice on the question of "how is restless legs syndrome caused", I hope it will be helpful to you, and I wish you good health!