What is the root cause of restless legs syndrome?

There are many reasons for this, and you still need to go to the hospital for examination. Restless legs often occur in the elderly, pregnant women, especially in the third trimester of pregnancy, diabetes, uremia patients. Some people believe that the reason why patients with restless legs syndrome have leg discomfort may be related to poor peripheral peripheral circulation, pregnant women, uremia patients, and diabetic patients may have a decline in peripheral vascular microcirculation, or peripheral nerve lesions, resulting in a decrease in their microcirculation ability and leg discomfort.

There is also an idea that restless legs syndrome is related to decreased ferritin utilization in the body, so people with anemia often have restless legs.

The main causes of restless legs syndrome are as follows: 1. Restless legs syndrome is mainly manifested by the patient's indescribable paresthesia or uncomfortable feeling in both lower limbs when he is quiet or sleeping at night, and has the desire to move his legs. At present, it is not very clear, and some patients have a certain relationship with heredity.

2. Some patients are prone to restless leg syndrome due to the lack of trace elements in the body, such as iron deficiency. 3. There is also a part related to the excitatory neurotransmitters of the central nervous system, such as the increase of excitatory amino acids, so restless legs syndrome is related to genetic factors, iron deficiency in the body, and the release of excitatory amino acids in the brain.

The cause of the disease is unknown. It is often complicated by gastric surgery, uremia, alcoholism, and psychiatric factors are of certain importance to the pathogenesis. In particular, symptoms occur when conceiving, watching movies, and plays.

It is thought to be autonomic dysfunction. Infectious diseases, vitamin deficiencies, diabetes mellitus and various anemias may be the most important factors. It is thought to be an autosomal dominant disorder that can occur in several people in the same family.

2] The use of phenylthiazide has been mentioned, and abrupt discontinuation of barbiturates can induce the disease. Some believe that the most likely cause is an abnormal build-up of metabolites in the muscles. It has also been reported to be related to inadequate CAPD (peritoneal dialysis) or impaired local circulation.

There are two types of disease: primary and secondary. Among them, the primary ** is unknown, and children often have a family history of heredity. Secondary is common due to the following causes:

Uremia, iron deficiency anemia, folate deficiency, pregnancy, rheumatoid arthritis, Parkinson's disease, multifocal neuropathy, metabolic disorders, and drugs.

Restless legs syndrome is complex and unknown in Western medicine, and the following factors are thought to be related to the onset.

1.Genetic factors.

Ekbom (1960) suggested that the pathogenesis of RLS was genetically related, with 43% of the reported patients having similar disorders in their relatives, and several families were dominantly inherited.

2.Doctrine of ischemia.

RLS usually occurs during quiet rest, but it can also occur during long-term work in cold environments, and symptoms are often relieved by activity, compression, thrashing of local muscles, or the use of vasodilators. In some patients, limb blood flow studies also show decreased blood flow. Based on the above facts, many scholars believe that this disease is caused by local tissue blood circulation disorders, resulting in tissue hypoxia and metabolite accumulation.

3.Endocrine factors.

RLS is also common in pregnant women. Retrospective diagnosis was made in 486 newly born women and the disease was found. Jolivet (1953) reported that 27% of pregnant women had RLS.

At present, restless legs syndrome is considered to be a central nervous system disorder, and the specifics have not been fully clarified. It is mainly divided into primary and secondary.

1.Primary It is thought that it may be related to genetics, abnormal dopamine function in the brain.

2.Secondary Many diseases are predisposed to be associated with restless legs syndrome, such as patients with advanced renal failure, hemodialysis patients, polyneuritis, rheumatoid arthritis, Parkinson's disease, Sjögren's syndrome, pregnant women, anemia, and iron deficiency. Some studies suggest that 65 patients have reduced cerebrospinal fluid iron levels and that symptoms improve with oral or injectable iron.

Restless legs syndrome is a condition in which the patient feels indescribably uncomfortable in both lower limbs when it is time to fall asleep at night, forcing the patient to walk on the ground to relieve the symptoms, and the patient may present with uncomfortable or burning sensation in the lower limbs. The reasons for its formation are not well understood, but they can be mitigated in several ways: Eggplant.

1. It is recommended to give patients some pre-drug flushing and closures, such as oral methylcobalamin and vitamin B1 to nourish the nerves**. Second, patients can be given anti-anxiety and antidepressant drugs, such as sertraline hydrochloride, which also has a certain relief for restless legs syndrome. 3. Use traditional Chinese medicine to alleviate symptoms, such as Huixi oral traditional Chinese medicine to promote blood circulation and remove blood stasis, such as Shuluo Ning leg soup or acupuncture and moxibustion to improve symptoms.