What causes restless legs syndrome

The causes of restless legs syndrome are as follows:1Anemia:

Such as iron deficiency anemia; 2. Diabetes: It can cause peripheral neuropathy, especially peripheral neuropathy, and patients have discomfort in both lower limbs; 3.Uremia:

After kidney failure, toxins in the blood cannot be excreted through the kidneys and accumulate in the body, which will also lead to peripheral neuropathy and restless legs syndrome; 4.Neoplastic diseases: the immune response of the tumor leads to peripheral nerve damage; 5. Thyroid dysfunction, poisoning, certain drugs, etc.

It usually refers to an unbearable and uncomfortable feeling in the deep calf at rest, which can be relieved by exercise and rubbing. The cause of restless legs syndrome is currently considered to be a disease of the central nervous system, and the specific ** is not well understood. It is generally divided into primary and secondary.

Patients with primary restless legs syndrome often have a family history, and secondary restless legs syndrome usually includes pernicious anemia, maternal or maternal syndrome, renal syndrome, rheumatic disorders, Parkinson's disease, hereditary motor sensory peripheral neuropathy, and spinocerebellar ataxia.

The cause and pathogenesis of the disease are not particularly clear, and it is believed that this disease has a certain relationship with the nerves and spirit, and the disorder of blood circulation in the soles of the feet or the accumulation of tissue metabolites may lead to the onset of the disease.

The cause of restless legs syndrome is not well understood, but may be due to iron deficiency anemia, rheumatic disorders, and Parkinson's disease. Patients should follow the doctor's instructions to use dopaminergic drugs, and it is best to find out the active primary disease in time.

The cause of primary restless legs syndrome is often unclear and may be genetic; Secondary restless legs syndrome is often associated with a variety of disorders or drug use.

What are the causes of restless legs syndrome?

Primary restless legs syndrome.

May be related to genetics, abnormal dopamine function in the brain.

Secondary restless legs syndrome.

Many disorders predispose to restless legs syndrome, such as chronic renal failure.

Polyneuritis, rheumatoid arthritis.

Parkinson's disease. Sjögren's syndrome.

Iron deficiency anemia.

Folic acid. and vitamin B12 deficiency, in addition, hemodialysis, history of use of special drugs, etc. can also lead to the disease.

** of restless legs syndrome is currently unknown. It is currently classified as a sleep disorder, and some people classify it as an extrapyramidal disease. Because several drugs for restless legs syndrome are dystonia drugs for extrapyramidal diseases, it is also attributed to extrapyramidal movement disorders.

The symptoms of restless legs syndrome are mainly normal during the day, and when you are resting quietly, there is an indescribable soreness, numbness, swelling, pain, and indescribable uncomfortable feeling in the deep part of your calves, and sometimes you must massage with your hands, or hammer, get out of bed and walk to reduce the symptoms, so it will seriously affect the patient's sleep. **At present, drugs are mainly used dopamine receptor agonists, monoamine oxidase B inhibitors or antiepileptic drugs, as well as some sedative and sleeping drugs**.

1. Hereditary causes: Restless legs syndrome has a certain genetic predisposition, so patients should pay special attention to familial genetic diseases. If someone in the family suffers from a movement disorder or other disease, the probability of their close relatives suffering from restless legs syndrome is relatively high, so it should be treated in time to effectively prevent the disease and eliminate hidden dangers.

2. Symptoms caused by diseases: some systemic diseases will also lead to the occurrence of restless leg syndrome in patients, if patients have iron deficiency anemia or chronic renal failure and other diseases, they will cause restless legs syndrome, which will also have a great impact on the health of patients.

3. Other reasons: If there is abnormal dopamine function in the brain, polyneuritis and other diseases, there may be restless leg syndrome, patients due to Sjogren's syndrome, will lead to low body immunity, will also cause symptoms of malnutrition, if you do not pay attention to dietary conditioning long-term trace element deficiency, it will also cause restless leg syndrome, so you should check your body regularly and do a good job of prevention.

Restless legs syndrome has a greater impact on people's health, so we should choose a suitable method, through drugs or daily physical health care can effectively improve the condition, patients with restless legs syndrome should often go to the hospital for physical examination, through drugs or self-massage methods, can effectively improve the symptoms of physical discomfort, alleviate the condition, usually should have a good life and diet rules, effectively improve human immunity, to avoid the emergence of diseases.

The onset of restless legs syndrome may be caused by abnormal dopamine function in the brain, or it may be caused by low immunity in the body, and it can also lead to the onset of the disease if you live in poor conditions for a long time. During the onset of the disease, there will be discomfort in the lower limbs, itching in the lower limbs, and as the condition worsens, it may lead to movement disorders.

There are many causes of restless legs syndrome, and numerous studies have shown that the disease is related to dopaminergic neuronal damage in the central nervous system, and the deficiency is also an important cause because iron in the blood affects dopamine synthesis and leads to the formation of the disease.

At present, the causes of restless legs syndrome are mainly believed to be related to the following causes:

1. Caused by the imbalance of the brain neurotransmitters dopamine and acetylcholine;

2. Due to the lack of trace elements, iron and zinc;

3. Metabolic factors may cause liver and kidney insufficiency and electrolyte imbalances;

4. Due to psychological factors, psychological disorders can lead to restless legs syndrome.

At present, it is believed that restless legs syndrome is the result of a combination of various causes, ** is also to give adjustment of dopamine, and supplement trace elements, adjust psychology**, etc., to improve symptoms.

(1) The cause of the disease.

The cause and pathogenesis of this syndrome are not well understood, but it is believed to be related to various factors such as nerves and psychiatry, and some people speculate that it is related to the accumulation of tissue metabolites caused by blood circulation disorders in the feet based on the characteristics of the onset of the disease at rest and the relief of symptoms after exercise. It is also believed that this syndrome is more common in peripheral neuropathy caused by anemia, diabetes, alcoholism, and vitamin deficiencies, so it is speculated to be related to metabolic disorders.

Traditional Chinese medicine believes that this disease is caused by the stagnation of the skin, stagnation of the veins, or the deficiency of yin and blood, and the loss of nourishment of the meridians and skin. Its disease location is mainly in the meridians and skin, and is related to the heart, liver and kidney; Its pathology is based on false standards.

ii) Pathogenesis.

The pathogenesis of this syndrome is not well understood, but it has been speculated that it is related to the accumulation of tissue metabolites caused by impaired blood circulation in the feet. It is also believed that this syndrome is more common in anemia, diabetes, alcoholism, and vitamin deficiencies, so it is considered to be a metabolic disorder.

Clause. 1. The occurrence of restless legs syndrome will cause pain in the legs of patients, and the cause of its occurrence is related to the primary genetic abnormality, which is in the embryonic stage, and this disease is related to genetic factors. Genetic testing is needed to find out after the disease, especially if both parents have restless legs syndrome, and the likelihood of children suffering from restless legs syndrome is greatly increased.

Clause. 2. If restless legs syndrome is related to secondary diseases, it is related to iron deficiency anemia, pregnant women, maternal, kidney diseases, rheumatic diseases, diabetes, Parkinson's and other diseases. Therefore, the congenital and acquired factors of restless legs syndrome are different, and after the occurrence of the disease, what should be done, there should be a correct and effective stage, and patients should also know more about the understanding of restless legs syndrome.

The above we have made a brief introduction to the two causes of restless legs syndrome, after the occurrence of the disease, it can be improved according to the patient's **, if it is a congenital disease, the process will be more difficult, and it can only be controlled by drugs first, if it is caused by acquired diseases, you can choose dopamine drugs to carry out**, such as macazepine drugs, which can effectively ** restless legs syndrome, but it is necessary to deal with it according to the patient's different conditions. This can help patients recover more quickly from restless legs syndrome.

The cause of restless legs syndrome may be hereditary, and may be related to drugs or a variety of diseases, such as chronic kidney failure, iron deficiency anemia, Sjogren's syndrome, Parkinson's disease, rheumatoid arthritis, and polyneuritis. Unbearable pain occurs at rest, but it will be relieved after massage or a little exercise.

Primary restless legs syndrome.

The specific cause of primary restless legs syndrome is not well understood, but it may be related to genetics and abnormal dopamine function in the brain.

Secondary restless legs syndrome.

Secondary restless legs syndrome has a variety of causes, including spinocerebellar ataxia, peroneal muscular atrophy, Parkinson's disease, rheumatic diseases, iron deficiency anemia, uremia, pregnancy, etc.

**。The pathogenesis of restless legs syndrome is still unclear, and it is generally related to genetics, other diseases, drugs, substance deficiencies and other factors, and can occur in all ages, but it is more common in middle-aged and elderly people.

Restless legs syndrome is a common sensorimotor disorder that mainly affects the legs, its clinical manifestations are indescribable paresthesias and discomfort in the lower limbs at rest, a strong desire to move the legs, the patient is constantly forced to knock the lower limbs to relieve the pain, often aggravated at night rest, it is not completely clear, there are several theories.

Primary restless legs syndrome may be related to genetic, abnormal dopamine function in the brain.

Many diseases predispose to secondary restless legs syndrome, such as chronic renal failure, polyneuritis, rheumatoid arthritis, Parkinson's disease, Sjogren's syndrome, etc.

Restless legs syndrome is a disease of the central nervous system, and the specifics have not been fully elucidated. It is mainly divided into primary and secondary, and patients with primary restless legs syndrome often have a family history

Restless legs syndrome is a sleep-related movement disorder, the main clinical manifestation is in the evening or night, in the state of rest or inactivity, the patient feels uncomfortable in the legs, has a strong spike Zen imitation of the urge to move the legs, and the symptoms can be partially or completely relieved after getting out of bed and walking and other activities. Prolonged restless legs syndrome can lead to a decrease in sleep quality, anxiety, worry, distress, forgetfulness, lack of concentration and other uncomfortable symptoms, thus affecting normal study, work and life. The status of restless legs syndrome is currently unclear, but it is thought to be related to genetics, iron deficiency in the brain, and abnormal dopamine regulation in the central nervous system, which is common during pregnancy and chronic renal failure, and when taking certain medications such as antidepressants.

Restless legs syndrome is a sleep-related movement disorder, the main clinical manifestation is in the evening or night, in the state of rest or inactivity, the patient feels uncomfortable in the legs, has a strong urge to move the legs, and the symptoms can be partially or completely relieved after getting out of bed and walking.

Restless legs syndrome has been found to be mainly due to iron deficiency.

Restless legs syndrome has been found to be mainly due to iron deficiency. Iron deficiency can lead to anemia and can also lead to restless legs. Because iron is an important raw material for the synthesis of a neurotransmitter, or coenzyme.

When iron is deficient, there is a lack of synthesis of neurotransmitters and a disorder of brain function. This disorder is usually more pronounced at night, when the patient has limb tremors.

The cause of restless legs is likely to be neurological diseases, mental and psychological factors, and if you have a bad mood, it is likely to cause restless legs syndrome, or it may be a disease caused by physical abnormalities. During the onset of the disease, it is likely to cause paresthesia in both lower limbs, and the movement of the legs is restricted, which will affect the normal life, mainly through exercise and massage and other methods to reduce local pain, and can usually promote blood circulation and reduce the pain of both lower limbs by constantly patting.

The ** of restless legs syndrome may have 1, genetic inheritance, the disease has familial aggregation phenomenon 2, neurosubstance, patients may have nerve fiber lesions, nerve conduction abnormalities, spinal cord lesions, etc. 3, neurotransmitter dysfunction, dopaminergic neurological abnormalities, opioid system dysfunction, etc. 4, iron deficiency, iron deficiency anemia patients often develop restless legs syndrome, in addition to iron deficiency caused by advanced kidney disease and gastric cancer surgery, there will also be secondary restless legs syndrome.

The clinical symptoms of restless legs syndrome are as follows:

First, the patient has a strong desire to move the legs, and the lower extremities are often accompanied by very uncomfortable paresthesias. Symptoms are evident during quiet rest, prolonged sitting, lying down, and at night. Symptoms may be relieved by activity or by thrashing both lower limbs.

Second, the distal limbs of the patient will have numbness, ant walking, burning pain, and a small number of patients have very obvious pain. Sensory symptoms can involve the ankles, knees, and even the entire lower extremities, with nearly half of patients affecting the upper extremities.

Third, most patients have periodic limb movements, which manifest as repetitive triple flexion of the hip, knee, and ankle during sleep, resulting in dorsal extension of the toes.

Fourth, 95% of patients experience insomnia because they are very uncomfortable at night.