How to prevent thrombocytopenic purpura in pregnant women?

There are two forms of thrombocytopenic purpura, one is primary; One is secondary. Primary thrombocytopenic purpura is an autoimmune disease that occurs most often in pregnancy. The clinical manifestations are mainly mucosal and subcutaneous hemorrhage.

Secondary thrombocytopenic purpura is caused by infections, drug allergies, and blood disorders.

Pregnancy itself does not aggravate its condition, but it has a certain risk to the mother and child, and the pregnant mother may have bleeding tendency, miscarriage, placental abruption, intrauterine fetal death, birth canal bleeding and hematoma, postpartum hemorrhage, abdominal wound bleeding and hematoma, and in severe cases, visceral hemorrhage and life-threatening.

The fetus can enter the fetal blood circulation through the placenta due to the antiplatelet antibodies in the maternal blood circulation, so that the fetal platelets are rapidly destroyed, neonatal thrombocytopenia, and intracranial hemorrhage occurs, and the perinatal mortality rate is 10% to 30%. For example, if a pregnant woman has had thrombocytopenic purpura for many years, her condition is stable in the first trimester, and her platelets are greater than 50 109 liters. And the bleeding tendency is light, only the platelet value is low or slightly fluctuating, and there will be no obvious changes after pregnancy, often no special **, pregnancy will not be too much problem.

In the middle and late stages, the clinical symptoms are severe, there is a tendency to bleed, and hormones can be used**; If hormones** are ineffective and symptoms are significant, or even life-threatening, splenectomy can be performed before 6 months of pregnancy. If neither of these methods is effective, it is best to stop the pregnancy.

It is best to meet your own conditions, and the doctor will formulate a plan according to your actual situation. 0311-6750-2707-

There are several aspects to thrombocytopenic purpura prevention:

First, prevent it from happening. The main thing for children is to prevent infection.

Second, once infected, try to reduce the use of drugs that cause thrombocytopenia as much as possible. For example, antipyretic analgesics, and some antibiotics should be avoided if not indicated.

Third, if you have thrombocytopenic purpura, you need to normalize it. Be sure to follow the doctor's instructions, for example, some parents are particularly afraid of hormone drugs in the process, but some stages must be used, must be used, and must be used for a full course of treatment, and can not reduce the dose by themselves, if this is done, thrombocytopenia, **is very smooth, **is also very little.

Fourth, thrombocytopenic purpura, once it is aggravated, it is necessary to seek medical attention in time.

There are two forms of thrombocytopenic purpura, one is primary; One is secondary Primary thrombocytopenic purpura is an autoimmune disease, and the onset of pregnancy is mostly this clinical manifestation is mainly mucosal and subcutaneous hemorrhage Secondary thrombocytopenic purpura is caused by infection, drug allergies, and blood disorders

Pregnancy itself does not aggravate its condition, but it has a certain risk to the mother and child, and the pregnant mother may have bleeding tendency, miscarriage, placental abruption, intrauterine fetal death, birth canal bleeding and hematoma, postpartum hemorrhage, abdominal wound bleeding and hematoma, and in severe cases, visceral hemorrhage and life-threatening.

The fetus can enter the fetal blood circulation through the placenta due to the antiplatelet antibodies in the maternal blood circulation, so that the fetal platelets are quickly destroyed, neonatal thrombocytopenia, and intracranial hemorrhage occurs, and the perinatal mortality rate is 10% 30% If a pregnant woman has suffered from thrombocytopenic purpura for many years, her condition is stable in the first trimester, the platelets are greater than 50 10 9 l and the bleeding tendency is mild, and only the platelet value is low or slightly fluctuating, and there will be no obvious changes after pregnancy, and no special ** is often required. There won't be much of a problem with getting pregnant

In the middle and late stages, the clinical symptoms are severe, there is a tendency to bleed, and hormones can be used**; If hormones** are ineffective and the symptoms are obvious or even life-threatening, splenectomy can be performed before 6 months of pregnancy If neither of these methods is effective, it is best to stop the pregnancy During pregnancy, patients need to pay attention to the following problems:

1) During pregnancy, careful monitoring should be carried out, that is, frequent examinations, regular laboratory tests of platelet count When the condition is relieved, platelets greater than 50 10 9 L, generally do not need **

2) For the first onset of pregnancy, adrenal corticosteroids should be used for those who have not been controlled for thrombocytopenic purpura during pregnancy** during pregnancy

3) If the condition is severe, fresh blood or platelet suspension can be concentrated

4) Splenectomy should not be performed during pregnancy, with a mortality rate of 10% Splenectomy is only used when hormone failure is uncontrollable and life-threatening, and it is best to perform it before 6 months of pregnancy, because surgery in the third trimester of pregnancy is also difficult to expose, so it should not be used

5) When the fetus is delivered, attention should be paid to suturing to stop bleeding, carefully checking the wound for hematoma, and paying attention to the prevention and treatment of puerperal infection

6) Many drugs, such as thiazides, aspirin, penicillin, streptomycin, etc., can be used as antigens to induce thrombocytopenic purpura, so pregnant women should be cautious about taking drugs, and should stop the drug in time once it occurs

7) Newborn platelet count should be routinely checked, if platelets are less than 50 10 9 L, hormones should be given Neonates should be artificially fed, so as to avoid thrombocytopenia due to milk inhalation

There are two forms of thrombocytopenic purpura, one is primary; One is secondary Primary thrombocytopenic purpura is an autoimmune disease, and the onset of pregnancy is mostly this clinical manifestation is mainly mucosal and subcutaneous hemorrhage Secondary thrombocytopenic purpura is caused by infection, drug allergies, and blood disorders

Pregnancy itself does not aggravate its condition, but it has a certain risk to the mother and child, and the pregnant mother may have bleeding tendency, miscarriage, placental abruption, intrauterine fetal death, birth canal bleeding and hematoma, postpartum hemorrhage, abdominal wound bleeding and hematoma, and in severe cases, visceral hemorrhage and life-threatening.

The fetus can enter the fetal blood circulation through the placenta due to the antiplatelet antibodies in the maternal blood circulation, so that the fetal platelets are quickly destroyed, neonatal thrombocytopenia, and intracranial hemorrhage occurs, and the perinatal mortality rate is 10% 30% If a pregnant woman has suffered from thrombocytopenic purpura for many years, her condition is stable in the first trimester, the platelets are greater than 50 10 9 l and the bleeding tendency is mild, and only the platelet value is low or slightly fluctuating, and there will be no obvious changes after pregnancy, and no special ** is often required. There won't be much of a problem with getting pregnant

In the middle and late stages, the clinical symptoms are severe, there is a tendency to bleed, and hormones can be used**; If hormones** are ineffective and the symptoms are obvious or even life-threatening, splenectomy can be performed before 6 months of pregnancy If neither of these methods is effective, it is best to stop the pregnancy During pregnancy, patients need to pay attention to the following problems:

1) During pregnancy, careful monitoring should be carried out, that is, frequent examinations, regular laboratory tests of platelet count When the condition is relieved, platelets greater than 50 10 9 L, generally do not need **

2) For the first onset of pregnancy, adrenal corticosteroids should be used for those who have not been controlled for thrombocytopenic purpura during pregnancy** during pregnancy

3) If the condition is severe, fresh blood or platelet suspension can be concentrated

4) Splenectomy should not be performed during pregnancy, with a mortality rate of 10% Splenectomy is only used when hormone failure is uncontrollable and life-threatening, and it is best to perform it before 6 months of pregnancy, because surgery in the third trimester of pregnancy is also difficult to expose, so it should not be used

5) When the fetus is delivered, attention should be paid to suturing to stop bleeding, carefully checking the wound for hematoma, and paying attention to the prevention and treatment of puerperal infection

6) Many drugs, such as thiazides, aspirin, penicillin, streptomycin, etc., can be used as antigens to induce thrombocytopenic purpura, so pregnant women should be cautious about taking drugs, and should stop the drug in time once it occurs

7) Newborn platelet count should be routinely checked, if platelets are less than 50 10 9 L, hormones should be given Neonates should be artificially fed, so as to avoid thrombocytopenia due to milk inhalation

In the middle and late stages, the clinical symptoms are severe, there is a tendency to bleed, and hormones can be used**; If hormones** are ineffective and symptoms are significant, or even life-threatening, splenectomy can be performed before 6 months of pregnancy. If neither of these methods is effective, it is best to stop the pregnancy. During pregnancy, there are a few things to be aware of:

1) During pregnancy, careful monitoring should be carried out, that is, frequent check-ups and regular laboratory tests of platelet count. When the disease is in remission and platelets are greater than 50 10 9 L, ** is generally not required.

2) For the first onset of pregnancy, adrenal corticosteroids should be used for those who have not been controlled for thrombocytopenic purpura during pregnancy** during pregnancy

3) If the condition is severe, fresh blood or platelet suspension can be concentrated

4) Splenectomy is not suitable during pregnancy, and the mortality rate is 10%. Splenectomy is only used when hormone failure is uncontrollable and life-threatening bleeding is preferably performed before 6 months of pregnancy, but surgery is not suitable because of the difficulty of exposure in the third trimester.

5) When the fetus is delivered, attention should be paid to suturing to stop bleeding, carefully checking the wound for hematoma, and paying attention to the prevention and treatment of puerperal infection

6) Many drugs, such as thiazides, aspirin, penicillin, streptomycin, etc., can be used as antigens to induce thrombocytopenic purpura, so pregnant women should be cautious about taking drugs, and should stop the drug in time once it occurs

7) Newborn platelet count should be routinely checked, if platelets are less than 50 10 9 L, hormones should be given. Newborns should be artificially fed to avoid thrombocytopenia due to milk pumping.