Late Parkinson s Disease Symptoms, What Are the Symptoms of Advanced Parkinson s Disease?

Hello, when Parkinson's disease progresses to an advanced stage, there will be the following symptoms.

1. Drooling.

There are many patients with symptoms of advanced Parkinson's disease who often drool, and in severe cases, they need to be wiped constantly with a handkerchief. The study found that the patient's saliva secretion did not increase, but because Parkinson's patients had difficulty swallowing reflex, the reduction of automatic swallowing action caused saliva to accumulate in the oral cavity, and the amount of saliva would flow out automatically.

2. Pain Many patients will experience pain, although it is not severe enough to have to take painkillers, but the pain can sometimes be very distressing to patients. The manifestations of pain are multifaceted, and can be manifested as shoulder and neck pain, headache, low back pain, and the most common symptom is soreness in the arms or legs, and local muscle stiffness is the main cause. This is also very evident in the symptoms of advanced Parkinson's disease.

3. Constipation Some Parkinson's patients will have constipation in the late stage of the disease, in fact, constipation is a complication of Parkinson's disease, when the patient has severe constipation, the patient can go to the gastroenterology department of the hospital to do a comprehensive intestinal examination, under the guidance of the doctor, the appropriate amount of medication can be used**, but do not take the medicine without authorization. Patients can also change their diet to eat enough foods containing dietary fiber and drink enough water every day. Slows down the likelihood of constipation.

Paralysis of late symptoms of Parkinson's!

Late symptoms of Parkinson's disease? Hello, Parkinson's disease is not an incurable disease, it can be **! Moreover, early and systematic ** can greatly alleviate symptoms and improve the quality of life of patients!

But to choose a scientific method is key, now cell penetration repair has certain advantages in the field of the disease, and I hope that patients can try**.

1. The tremor will gradually worsen in the later stage of the patient, and at the beginning of the disease, it may be a limb tremor, and as the disease progresses, all four limbs can tremble, and even the head will swing in severe cases, and the tongue will also tremble, and the shaking amplitude will increase. Therefore, the daily life of such patients will be greatly affected, such as when eating and drinking soup, the soup is easy to spill due to the shaking of the limbs, or the rice is easy to fall out;

2. Patients with muscle rigidity will be unable to get out of bed slowly due to the gradual decline in exercise ability and worsening muscle activity due to the gradual decline of muscle ability, so it is basically a bedridden state, which is a final state, so Parkinson's disease itself will not be fatal, but such patients will eventually die due to long-term bed rest, secondary lung infection or pressure ulcers, pneumonia, etc.

Late symptoms of Parkinson's disease are resting tremor, clumsiness, bradykinesia, rigidity, and gait disturbances. Resting tremor may lessen or stop with voluntary movement or sleep. Hand movements become slower, initiation is difficult, and active movements are lost.

Facial expressions and movements are reduced, blinking eyes are reduced, it is difficult to maintain body balance, walking is unable to stop, and falls frequently. Other accompanying symptoms such as anxiety, sleep and cognitive impairment, poor memory, and unresponsiveness may also occur.

Hello, Parkinson's disease is a relatively common senile disease, most of them in the middle and late stages of the disease, there will be a significant decline in the patient's self-care ability, the quality of life is relatively poor, at this time it is necessary to strengthen the escort to prevent some secondary damage.

The late symptoms of Parkinson's disease are characterized by motor symptoms, psychiatric symptoms, and autonomic symptoms that gradually worsen

First, motor symptoms are manifested as dyskinesia or akinesia, difficulty initiating voluntary movements, decreased movement, decreased spontaneous automatic movements, decreased motor amplitude, and patients in the terminal stage can only be paralyzed in bed. Due to the decline in muscle function, it is easy to develop pneumonia, bedsores, etc.

Second, patients with psychiatric symptoms have aggravated depression and anxiety, and even patients have hallucinations after taking medication, mainly visual hallucinations, and will see vivid phantoms that do not exist in life, and patients are easy to hurt themselves or their families.

Third, autonomic dysfunction, such as obvious sweating, dyspepsia, intractable constipation, restless sleep at night, and some patients are complicated by restless legs syndrome. In addition to early symptoms such as resting tremor, muscle rigidity, and bradykinesia, patients with advanced Parkinson's disease may experience postural gait disturbances, loss of postural reflexes, difficulty maintaining balance, and slight uneven pavements that may fall down faster and faster, and cannot be stopped. People with advanced Parkinson's disease cannot walk, and their feet feel as if they are standing on the ground.

In addition to dyskinesia, they also have difficulty swallowing and may choke when eating and drinking. In addition, depression, anxiety, sleep disturbances, cognitive impairment, fatigue, and other non-motor disorders can occur in the advanced stages of Parkinson's disease.

Parkinson's disease is a group of unspecified diseases, and there is currently no definite way to deal with this disease, after which symptoms can be improved and discomfort can be delayed through relevant measures. The symptoms of patients with advanced Parkinson's disease will become more and more severe, and when they reach the advanced stage, they will have the following very serious symptoms and manifestations.

1. Patients will have strong tremor and shaking, and patients in advanced stages will not only have strong tremor and shaking of limbs, but also the swing amplitude of the tongue and head will also increase significantly.

2. Patients will have severe impairment of motor nerve function, and muscle stiffness will be more serious in patients with advanced Parkinson's disease.

3. Patients with advanced stage will have severe damage to the nervous system.

4. It can cause brain lesions, such as cerebral cardiovascular and cerebrovascular diseases, cerebral arteriosclerosis and atherosclerosis.

5. Patients in the advanced stage of Parkinson's disease will be bedridden, which is also the final state of this disease, and patients who have been bedridden for a long time are prone to form pressure ulcers.

6. Lung infections and lung diseases will occur in advanced patients, which will seriously affect the quality of life of patients.

The late symptoms of Parkinson's disease include the following: 1. Muscle stiffness and rigidity throughout the body, and the stiffness and rigidity of the muscles of the whole body, including the throat and respiratory muscles, in the later stage of Parkinson's disease, and the efficacy of the drug at this time is gradually decreasing, so patients will have difficulty swallowing, respiratory restriction and turning over disorder, which often leads to complications such as pneumonia and malnutrition. 2. Dementia, 15%-30% of Parkinson's patients will have a general decline in cognitive function or even dementia in the late stage, in addition to the decline in memory, calculation, language ability and executive ability, the patient's ability to take care of himself is also completely lost, unable to complete the basic living, washing and toileting, and needs to be taken care of by others.

3. Psychiatric symptoms, some patients may have psychiatric symptoms such as hallucinations and delusions in the advanced stage of the disease. 4. Dyskinesia is due to the reduced efficacy of drugs in the advanced stage of the disease and the excessive dose of levodopa, and the patient may have whole body chorea-like movements. In addition, sleep disturbances, anxiety, depression, restless legs syndrome are also common symptoms in the advanced stages of Parkinson's disease.

If Parkinson's disease does not go through a regular **, the course of the disease progresses rapidly, that is, the patient does not exceed three years from the onset to the advanced stage, and the patient with advanced Parkinson's disease is completely unable to move, and basically bed rest is the mainstay. The main symptoms of the patient are limb stiffness, difficulty turning over, and inability to eat independently. Some patients may even induce aspiration pneumonia due to aspiration of ingestion, which can lead to the death of Parkinson's patients.

Late symptoms of Parkinson's disease include:

1. Dyskinesia or inability to move, difficulty in initiating voluntary movements, reduced spontaneous and automatic movements, and reduced range of movements.

2. Ankylosis is muscle stiffness, resulting in stiffness of the muscles of the limbs, neck and face, and a sense of labor, heaviness and weakness during limb movement.

3. Tremor is manifested as a slow rhythmic tremor, which often starts from one finger and spreads to the entire upper limbs, lower limbs, jaw, lips and head.

In the late stage of Parkinson's disease, neuronal damage in the brain is more severe, and in many patients, in addition to difficulty in movement, the isoaxial symptoms of postural balance disorders may be more obvious, and patients are prone to falls, trauma, fractures, and then continue to stay in bed.

The symptoms of advanced Parkinson's disease are mainly manifested in the almost complete loss of self-care ability, difficulty swallowing, and unclear speech.

Tremor symptoms will appear obvious at the beginning, and tremor will be more severe in the later stages of the disease, first appearing in the distal upper limbs, and with the onset of the disease, the ipsilateral lower limbs will also develop, and there will be symptoms of muscle rigidity, muscle tone will be significantly increased, facial muscle rigidity, expressionlessness, and slow movement will be reduced. Patients blink infrequently, speak in a low voice, and have impaired posture and gait, and the shape looks a bit like a hunched back, all of which are late symptoms of Parkinson's disease.

The four main symptoms of people with Parkinson's disease are tremor, muscle rigidity, bradykinesia, and postural gait abnormalities. Tremor and muscle rigidity are more important features, so there are generally two main types of late symptoms, as follows:1

In people with tremors, tremors gradually worsen later in life. At first, one limb may tremble. As the disease progresses, the limbs may tremble throughout.

In severe cases, even the head will swing, the tongue will vibrate, and the amplitude of the vibration will increase. 2.In advanced stages, patients with muscle rigidity will not be able to get out of bed slowly due to the gradual decline in exercise capacity and the deterioration of muscle mobility, so they are basically in a state of ambulation, which is an advanced state, so Parkinson's disease itself is not fatal, but such patients will eventually die due to prolonged bed rest, secondary lung infections or pressure ulcers, etc.

The late manifestations of Parkinson's disease are mainly as follows:

Late manifestations of Parkinson's disease.

1. Parasomnias: Parasomnias are also common in patients with Parkinson's disease, including rapid eye movement sleep behavior disorder, restless legs syndrome, periodic leg movements, nocturnal myoclonus, and familiar nightmares, sleep terrors, etc. Among them, REM sleep behavior disorder refers to the patient's muscle relaxation during REM sleep, and spontaneous motor behavior disorder related to dream content, which can cause harmful behaviors, including self-harm or harm to the partner.

Late manifestations of Parkinson's disease.

2. Excessive sleepiness and sleep attacks during the day: Studies have shown that patients with Parkinson's disease will experience excessive sleepiness during the day, especially in the afternoon. If insomnia is more severe at night, the level of sleepiness during the day will be significantly worse.

However, there is a difference between this excessive sleepiness and sleep episodes. Sleep episodes are sudden, irresistible sleep phenomena that last from a few seconds to tens of seconds.

Late manifestations of Parkinson's disease.

3. Muscle rigidity: Muscle rigidity is one of the main symptoms of Parkinson's, mainly due to the increased equilibrium tone of the agonist and antagonist muscles. Due to the increase in muscle tone, it can bring a series of abnormal symptoms to the patient, such as blinking, chewing, swallowing, walking and other movements.

Late manifestations of Parkinson's disease.

4. Nighttime insomnia: emotional distress, nocturia, difficulty turning over, lower limb spasms, nightmares, etc., are important causes of nighttime insomnia. In addition, some ** medications can also cause nighttime insomnia.

If the patient already has insomnia, it may be further aggravated by Parkinson's disease for a variety of reasons.

Late symptoms: 1Emotional and intellectual changes:

Patients with Parkinson's disease may also present with psychiatric symptoms, which manifest as symptoms of depression and/or dementia. Some patients have indifferent expressions, depressed moods, slow responses, poor self-control, no self-confidence, pessimistic and misanthropic; Some show emotional anxiety, suspiciousness, suspicion, stubbornness, fear, anger, etc. 2.

Hyposmia: Many people with Parkinson's disease have a reduced or absent sense of smell. The odor resolution test score showed that 90% of patients had a score below the normal range for distinguishing different odors, and 75% of patients had decreased sensitivity to the acute threshold.

These defects appear early and do not appear to be related to the duration of the disease. 3.Salivating:

Patients with advanced symptoms of Parkinson's disease who have lips that cannot be completely closed. Improving body posture can relieve salivation. When sitting, you can hold your chin with your hands and prop your head up.

Symptoms of advanced Parkinson's diseaseWhen walking, special equipment is needed to keep the lips closed. 4.Weight loss:

Weight loss, which is a more common symptom of late parkinson's disease, is caused by reduced food intake, but sometimes the cause is unknown. Weight loss usually occurs gradually, usually over several years. In a small number of patients, symptoms of advanced Parkinson's disease may occur for months or even weeks.

The adverse consequences of significant weight loss are weakness, decreased immunity, and susceptibility to diseases.

The most serious symptoms in the late stage of Parkinson's disease include muscle stiffness and dementia all over the body. Parkinson's disease is a degenerative disease of the central nervous system, which mainly involves the degeneration of dopamine nerve cells in the substantia nigra, mainly the degeneration of some cells that manage movement, sometimes it is difficult to turn around, and in severe cases, it will cause difficulty in turning over. The clinical symptoms are mainly characterized by resting tremor, bradykinesia, muscle rigidity and postural balance disorders, and the onset may be related to genetics, environment, advanced age, and oxidative stress.

It is recommended to give trihexyphenidyl, propiconide, scopolamine and other drugs**, which can effectively alleviate the condition. Get enough sleep, do more aerobic exercise, and take proper vitamin supplements.