Why are premature babies more susceptible to necrotizing enterocolitis?

However, combined with the analysis of clinical experience, the reason why some premature infants have neonatal necrotizing enterocolitis may be directly related to ischemia, hypoxia, or chain reaction caused by infection, which causes damage to the immature intestine of premature infants.

Analysis: Neonatal necrotizing intestinal occult colitis is a serious disease of the neonatal gastrointestinal tract, characterized by intestinal avascular necrosis, inflammation and bacterial overgrowth. A**gens or predisposing factors:

Severe systemic infection, hypoxia, improper feeding, umbilical vein cannulation, patent ductus arteriosus, application of indomethacin**patent ductus arteriosus, polycythemia, etc. Suggestions:**Standard:

The symptoms of Xiaoxiang poisoning disappeared, the child responded well, there was no vomiting and gastric retention, and there was appetite. Abnormal abdominal signs are completely absent, bowel sounds are normal, a small amount of stool is passed spontaneously, and occult blood in the stool is negative. Improvement Criteria:

Symptoms of infection and poisoning have been reduced, response has improved, gastric retention has decreased, abdominal symptoms and signs have decreased or disappeared, bowel sounds have recovered but are not normal, and there is no large amount of blood in the stool. Unhealed criteria: The child is in a critical state, vomiting, abdominal distention, blood in the stool, systemic complications are serious, and unhealed or progressed, which can be life-threatening.

Life care: Delaying feedings for days or weeks in very small or diseased preterm infants, followed by slowly increasing enteral feeds over several weeks, reduces the incidence of necrotizing enteric fibrillation.

Nenatal necrotizing enterocolitis is a disease that causes diffuse or partial necrosis of the small intestine and colon due to a variety of factors that cause intestinal mucosal damage, ischemia and hypoxia.

Causes: The causes of necrotizing enterocolitis in neonatal necrotizing enterocolitis have not been fully elucidated, but it is generally believed to be caused by a combination of causes, with preterm birth and infection being the most important in the grandchildren. 1.

Preterm birth Preterm birth is an important element of NEC, due to poor immune function, poor intestinal peristalsis, and suffocation at birth, resulting in hypoxic damage to the intestinal wall and bacterial invasion. 2.Infection Infection is one of the main causes of NEC, and most of them are intestinal bacteria such as Klebsiella, Escherichia coli, and Pseudomonas aeruginosa.

3.Hypoxia and ischemia in neonatal asphyxia, respiratory diseases.

Clinical manifestations: male infants are more common than female infants, mainly sporadic cases, and there is no obvious seasonality. Meconium is normal after birth, and the onset usually occurs within 2 to 3 weeks after birth, with a peak of 2 to 10 days.

NEC can also be mini-epidemic in the prevalence of neonatal diarrhoea, with no differences in gender, age, or season. 1.Abdominal distension and decreased bowel sounds Children have delayed gastric emptying, gastric retention, and then abdominal distention.

In mild cases, only abdominal distension is present, and in severe cases, the symptoms worsen rapidly, abdominal distension is like a drum, bowel sounds are weakened or even disappear, and NEC abdominal distension in premature infants is atypical. Abdominal distension and decreased bowel sounds are early symptoms of NEC, and changes in the frequency of abdominal distension and bowel sounds should be observed at any time in high-risk children.