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Behcet's syndrome (Behcet's disease)** is uncertain and may be related to genetic factors and pathogen infection, and some people believe that it is related to autoimmunity.
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1.Immune abnormalities: This disease is a common manifestation of humoral and cellular immunity, but it is generally believed that abnormal cellular immunity is closely related to the disease.
2.Viral infection: Viruses are thought to be the cause of Behcet's disease in the early stages. However, immunofluorescence was not further confirmed by tissue culture and serological animal inoculation.
3.Streptococcus: Some patients may also develop a range of diseases such as tonsillitis, pharyngitis, and periodontitis, so it is thought that the onset of Behcet's disease is related to the bacteria in these lesions.
4.Tuberculosis bacteria: Anti-tuberculosis** will not only have a significant effect on the primary lesion, but also improve the damage related to Behcet's disease, so it is considered to be a type of tuberculosis bacteria.
5.Trace elements: These can cause Behcet's disease, and a small number of patients have high levels of trace elements in diseased tissues such as vascular endothelial cells, macrophages, and aqueous humor, serum, and neutrophils, often more organochlorine, organophosphorus, and copper ions.
In general, the ** of Behcet's disease is not clear, but the onset is related to immune abnormalities, so in the process of immune regulation and inflammatory response, cellular components will also change, and a variety of active substances will be produced, such as plasmin inhibitors will cause the activity of plasmin to lyse fibrin is greatly reduced, resulting in an increase in fibrinogen content.
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1. Infection.
This is a relatively common cause of Behcet's disease, which can be divided into viral infection and bacterial infection, but research suggests that the occurrence of Behcet's disease is more related to the occurrence of chronic viral infection. In addition, it is also related to diseases such as tonsillitis, pharyngitis and periodontitis that often occur in patients.
2. Trace elements.
Some researchers have found that a variety of trace elements were found in the diseased tissues of patients, such as aqueous humor, sural nerves, macrophages and neutrophils, and the content in them exceeded normal values, mainly organic phosphorus and copper ions, which researchers speculated that this was related to the patient's occupation or environment.
3. Genetic factors.
The incidence of Behcet's disease is actually high in a certain area, especially in some Mediterranean countries, its incidence is higher, in addition, the incidence is also higher in some blood families, that is, people often say heredity, and mainly male patients.
4. Abnormal immunity.
Blood tests in patients with Behcet's disease can detect the presence of anti-oral mucosal antibodies and anti-arterial wall antibodies in the serum; In addition, a complex was found in the serum, which was positive for 60%, suggesting a relationship with Behcet's disease activity.
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Behcet's disease is an immune disease, everyone can suffer from immune diseases, and Behcet's disease is also known as Silk Road disease, it can be seen that it is more likely to occur along the Silk Road, the main dietary habits of this group of people are to eat more meat, drink more alcohol, rent less food, eat less lead ears of vegetables and fruits, etc. In addition, people who have been in a state of anxiety for a long time, have excessive work pressure, and have poor physical fitness are also prone to the occurrence of Behcet's disease. In addition, people with comorbid immune system disorders or long-term use of certain medications are also prone to Behcet's disease.
There are also some people who have settled in damp cold and smoke for a long time, and they may also be prone to Behcet's disease.
The general symptoms of Behcet's disease include mild fatigue and discomfort, and a small number of patients may also have dizziness, headache, joint pain, weight loss, etc. There are two types of onset: acute and chronic. Acute is rare, but the symptoms are more significant, and some may be accompanied by fever, and low-grade fever is more common. >>>More
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