What are the dangers of MND?

Motor neuron disease (MND) is a severe chronic progressive neurodegenerative disease, which is a progressive cause of harm to patients, seriously harming the physical and mental health of patients, and even leading to death, bringing great inconvenience to patients and their families.

Motor neuron disease is characterized by a combination of muscle weakness, muscle atrophy, bulbar palsy, and pyramidal tract signs due to upper and lower motor neuron damage. In the early stages of the disease, patients may present only with atrophy of the hand muscles and inflexibility. However, as the disease progresses, the symptoms of weakness and atrophy will gradually spread to all limbs, and eventually they will lose the ability to take care of themselves.

If respiratory muscles are involved, it can cause dyspnea; If the throat muscles are affected, it can make it difficult to swallow and eat. Patients are conscious, but unable to move independently, eat independently, and even have difficulty breathing, which can cause serious emotional and psychological problems, and at the same time, if the care is not thorough, it can produce complications such as ** infection, pressure ulcers, and lung infection.

In addition, the disease can affect the neurocognitive system, and patients often have symptoms such as executive dysfunction, inattention, personality mutations, irritability, and mental retardation, but the patient's memory is usually not affected. At present, there is no best way to treat the disease, and its overall prognosis is highly malignant, causing serious family burden and social burden.

Motor neurons are neurons that are responsible for transmitting messages from the spinal cord and brain to the muscles and endocrine glands that innervate organ activity. Motor neuron disease.

It is a rare disease, which is a series of chronic progressive neurodegenerative diseases characterized by motor neuron changes. At present, the cause of the disease is not clear, and patients present with muscle weakness, muscle atrophy, bulbar paralysis, etc., and usually have no paresthesias. The disease mostly occurs in middle-aged and elderly people, and the course of the disease is mostly 2 to 6 years, and most of them have a poor prognosis, and often die of respiratory muscle paralysis or lung infection due to respiratory muscle involvement.

Main**. Genetic factors.

MND is mostly sporadic, with a few family histories, and is inherited mainly in an autosomal dominant manner. The most common causative gene is the copper (zinc) superoxide dismutase (SOD-1) gene on chromosome 21.

Infection and immunity.

Some researchers believe that the onset of the disease may be related to poliovirus, enterovirus, and human immunodeficiency virus (HIV), and when the infection invades neurons, patients will have corresponding clinical manifestations.

Metallic elements. The onset of motor neuron disease may be related to certain metals, such as lead, mercury, aluminum, etc., and differences in the content of metal elements in the environment may also be responsible for the high incidence of geographical prevalence in some regions.

Nutritional disorders. Some researchers have found amyotrophic lateral sclerosis.

ALS) in the plasma of vitamin B1

and vitamin B1 monophosphate, which may lead to dystrophy of neurons, leading to amyotrophic lateral sclerosis.

Neurotransmitters. The level of the inhibitory neurotransmitter GABA in the cerebrospinal fluid of patients with ALS is significantly reduced, while norepinephrine.

Elevated, the more severe the disease, the more pronounced this change is, and there are also studies that show excitatory amino acids (mainly glutamate and aspartic acid.

The neurocytotoxic effects of ALS play an important role in the pathogenesis of ALS.

Symptom. Motor neuron disease usually has an insidious onset and a slow progression. Due to the different locations of injury, the clinical manifestations are different combinations of symptoms such as muscle weakness, muscle atrophy, and bulbar paralysis.

In many cases, one type of presentation is present, followed by another, and finally ALS. As a result, it can sometimes be difficult to determine which type it belongs to in the early stages of the disease.

**。There is still a lack of drugs that can effectively reverse or control the progression of the disease. The motor neuron disease pathogen is diverse and affects each other, so it must be a combination of multiple methods.

The ** of motor neuron disease includes **, symptomatic ** and various non-pharmacos**.

So so**. When patients develop muscle cramps, antispasmodic and analgesic drugs may be used symptomatically**.

When the patient progresses and respiratory failure develops, a noninvasive ventilator can be used as soon as possible to assist breathing, or tracheostomy and mechanical ventilation can be selected on a case-by-case basis.

Motor neuron disease is a disease that has a great impact on the motor function of the human body, and can cause paralysis in severe cases. Therefore, it is very important for patients to choose the best method at the best time, a good method can not only make the body less harmed, but also greatly reduce the cost, so patients must not delay the disease, timely treatment is the last word.

Motor neuron disease is a neurodegenerative disease that primarily affects the motor system and not the sensory system. Motor neuron disease (MND) also invades upper and lower motor neurons, and often begins with weakness of the small muscles in one hand, accompanied by atrophy, and gradually progresses to other limbs, eventually affecting the respiratory and swallowing muscles, causing dyspnea and swallowing.

Motor neuron disease often progressively worsens, the course of the disease is about 3-5 years, you can come to Beijing Renxuan TCM to find Sheng Jinqiangfu**, through Yiyuan Muscle Formula one-to-one conditioning, can improve the patient's symptoms.

MIN TCM belongs to the category of dysentery, and the soup of MIN Jin Quan Yuan can be used as a reference.

Motor neuron disease can manifest itself as weakness and atrophy of the limbs, clumsiness and weakness of finger movements, muscle weakness and atrophy as the disease progresses, extending to the trunk and neck, and finally involving the facial muscles and throat. Patients may have bulbar paralysis, mostly in the late stage, the tongue muscles are first involved, manifested as tongue muscle atrophy, fasciculation, and tongue protrusion weakness, followed by pharyngeal, laryngeal, and masticatory muscle atrophy and weakness, resulting in the patient's slurred arthria, dysphagia, chewing weakness, and the orbicularis oculi muscle in the facial muscle is more obviously involved. There is often a pattern of disease progression in MND, usually from the upper extremity that is first affected, then to the contralateral upper extremity, to the ipsilateral lower extremity, to the contralateral lower extremity, and finally to the bulb involvement.

Motor neuron disease can be life-threatening, mostly within 3 to 5 years, death from respiratory muscle paralysis or lung infection, so motor neuron disease is more harmful.

Motor neuropathy, commonly known as "ALS", is a chronic disease mainly of the locomotor system, which can cause progressive muscle weakness and atrophy of the limbs, and can also cause damage to respiratory muscles and throat muscles. Its main harm is to affect the patient's motor system, the patient has weakness in the limbs, with the prolongation of the disease, the patient gradually weakens, loses the ability to take care of himself, and finally can not get out of bed and move, unable to walk. If the pharyngeal muscles are involved, the patient has difficulty swallowing and eating, and if the respiratory muscles are involved, it can cause dyspnea and weakness of breathing, and a ventilator can be used to assist breathing.

Motor neuron disease (MND) is a series of chronic progressive neurodegenerative diseases characterized by upper and lower motor neuron damage. Motor neuron disease includes the following: damage is limited to lower motor neurons, and it is characterized by weakness and muscle atrophy without pyramidal tract signs, which is called progressive muscle atrophy; Patients who damage the motor nucleus of the medullary medulla alone and manifest as weak atrophy of the laryngeal and tongue muscles are called progressive bulbar palsy; Those who involve only the pyramidal tract and present with weakness and pyramidal signs are called primary lateral sclerosis.

1. It can cause muscle damage throughout the body.

Patients with motor neuron disease will have a generalized muscle injury closure judgment, and when muscle damage occurs, it will also affect the patient's motor system, which will cause the patient to have uncoordinated limb movements.

2. Muscle atrophy will occur when the patient is slippery.

Once the disease spreads after suffering from motor neuron disease, it will also cause great damage to the patient's body, which will cause muscle atrophy in the patient. When muscle atrophy occurs, it can also seriously affect the mental health of patients.

3. Cause quadriplegia.

Severe motor neuron disease can lead to quadriplegia and long-term bed confinement when paralysis occurs.

4. It will cause ventilator damage and dyspnea in patients.

Most patients with MND will experience ventilator damage and dyspnea, which may lead to respiratory failure and other complications.

Motor neuron disease is a very dangerous disease, after the diagnosis of this disease, do not delay the change, we must seize the first period, and take the best measures in time to prolong the survival period. Don't have too much emotional burden and stress after the illness, as bad emotions can also lead to aggravation of the disease. After the illness, it is necessary to strengthen the supplement of nutritious food, and reasonable supplementation of nutrients can improve the patient's immunity.

Motor neuron disease, commonly known as ALS, mainly affects the locomotor system, causing progressive muscle weakness and atrophy of the limbs, and can also affect the respiratory and throat muscles. The main harm lies in the impact on the patient's motor system, the patient has limb weakness, with the prolongation of the course of the disease, the patient's weakness gradually worsens, loses the ability to live independently, and finally lies in bed and cannot walk. If the laryngeal muscles are involved, the patient may have difficulty swallowing, eating, and if the respiratory muscles are involved, the patient may have difficulty breathing, weak breathing, and may need to be ventilated to assist breathing.

The main harm of motor neuron disease is muscle weakness, especially in the later stage of the disease, patients are manifested by muscle damage to various systems of the body, quadriplegia, etc., and even can only move one finger in the whole body, requiring long-term bed rest.

In addition, in advanced motor neuron disease, it can cause damage to the respiratory muscles, making it difficult to breathe, and most patients die from respiratory failure or other complications.

Therefore, MND is very dangerous and you should go to the hospital as soon as you develop symptoms**.

Motor neuron is also known as ALS, as the name of the disease suggests, patients will gradually appear as if they are "frozen", and the patient will gradually develop from limb weakness to muscle atrophy; The limbs gradually develop from the hands and feet, and eventually to the torso. Patients may experience dyspnea, dysphagia, and most eventually die of paralysis of the respiratory muscles. At present, Western medicine does not have a good method for motor neurons, but there is no way for motor neurons, and choosing the right professional method as soon as possible plays a vital role in motor neurons.

Motor neuron is an incurable disease, and the most important thing is to treat the symptoms**, so that it will slowly recover.

It usually occurs after the age of 40, and is more common in men than in women; Most patients begin with lower motor neuron damage in the unilateral upper extremity, characterized by inflexible and weak finger movements, and ipsilateral wrist extension.

Some patients present with whole or proximal upper extremity weakness; Subsequently, the small muscles of the hand, such as the thenar and vermiform muscles, atrophied and gradually developed into the forearm, upper arm and shoulder girdle muscles, and the extensor weakness was more significant than that of the flexor muscles. At the same time or later, spastic paralysis of the lower extremities, scissor gait, increased muscle tone, hyperreflexia, and positive Babinski sign occur, and a few cases begin in the lower extremities and gradually extend to both upper extremities.

The onset of the upper limb is about twice that of the onset of the lower limb. Distal muscle weakness is more common than proximal. Fasciculations are the most common symptom and can occur in multiple limbs and tongue.

Bulbar palsy usually develops late, but it can also occur soon after muscle atrophy in the hand. Rarely, it is the first symptom and presents with dysarthria, slurred speech, difficulty swallowing and chewing, and atrophy of the tongue muscles with tremor. Some patients may develop pseudobulbar paralytic affective disorder, such as forced crying and laughing.

Even if the brainstem is severely dysfunctional, the extraocular muscles are not affected and the sphincter is not involved.

Patients may have subjective paresthesias such as numbness and pain, but there is no objective sensory impairment even in the advanced stage of the disease; In some patients, paresthesias may be related to peripheral nerve impact.

The course of the disease continues to progress, eventually resulting in death due to respiratory muscle paralysis or concurrent respiratory tract infection; The survival time of the disease is as short as a few months, and the elderly are more than 10 years, with an average of 27-52 months.