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I'm sorry I don't know much about this question. However, the disease seems to be related to selenium deficiency.
Hope it helps.
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KBD is a common condition that can cause symptoms such as joint swelling and effusion, and most patients will be very interested in the common knowledge of KBD, so the following article will analyze what KBD is.
1.First of all: large bone joint disease refers to an endemic and deformed osteoarthrosis, which is also called dwarf disease and abacus bead disease in China, and is called Kaschin-Beck disease in the international medical community.
2.Secondly: KBD is mainly distributed in eastern Siberia and northern North Korea abroad, and has a large distribution range in China, from northeast to southwest in a wide area, mainly in Hei, Kyrgyzstan, Liao, Shaanxi, Jin and other provinces, mostly distributed in mountainous and semi-mountainous areas, and rare in plains.
3.Finally, KBD can occur in people of all ages in life, and it is most common in people such as teenagers and children.
Precautions. After understanding what KBD is, you should also pay attention to eating more sulfur-containing foods such as asparagus, eggs and garlic after discovering that you have KBD, because sulfur is used for the repair and reconstruction of bones, cartilage and connective tissues, and sulfur also helps calcium absorption.
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KBD is an endemic disease that causes bone and joint deformity, also known as dwarf disease. If the disease occurs in adolescence, there can be some early ossification of the bone fix, resulting in some of the appearance of this dwarfism, if it occurs before puberty, it will be manifested as the disease of osteoarthritis, including the bone friction, some joint pain, swelling and effusion, and some noose symptoms, and this disease, if there are pain or swelling symptoms, we should focus on anti-inflammatory and analgesic, if there are some joint deformities, then we use some surgical procedures**.
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In fact, it is the crane knee wind in traditional Chinese medicine.
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The occurrence and development of X-ray signs of KBD are specifically related to the age and location of onset. Therefore, the differential diagnosis should be differentiated from diseases such as achondroplasia, rheumatoid arthritis, traumatic or degenerative arthritis, etc.
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The ** of KBD is still unknown. Chronic oral poisoning was suspected but not confirmed. Most people think it may be related to pathogenic molds in grains.
Animal Experiment: Animals fed with grains with pathogenic molds have pathological changes similar to those of macroarthropathy. The causative mold may be Fusarium retention, but it has not been fully proven.
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