How much is docetaxel imported, and the reimbursement ratio of imported docetaxel

Docetaxel. It is a phase-m-phase specific drug, which can promote the polymerization of tubules into stable microtubules and inhibit their polymerization, so that the number of tubules is significantly reduced, and the microtubule network-like structure can be destroyed. Imported docetaxel drug** will be a little more expensive, but generally not more than 1,000 yuan.

Docetaxel is toxic and I recommend chemotherapy for patients.

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Drug**: Yuan.

Name of drug: Dopafil docetaxel.

Legal analysis: docetaxel needle (Tesotti) is included in the national health insurance list. However, the medical insurance list is different for each city and province, if you want to know whether the docetaxel needle wheel (Tesoti) is entered, you can consult the relevant department in your city.

Legal basis: Article 29 of the Social Insurance Law of the People's Republic of China Article 29 The part of the medical expenses of the insured persons that should be paid by the basic medical insurance** shall be directly settled by the social insurance agency and the medical institutions and drug business units. The administrative department of social insurance and the administrative department of health shall establish a settlement system for medical expenses for medical treatment in other places to facilitate the insured to enjoy basic medical insurance benefits.

There is no unified regulation on the reimbursement ratio of imported docetaxel, and the medical insurance catalogue of each city and the province with a wide cover is different. Docetaxel (Tesotti) is on the NHRD.

Proportion of import interest subsidy.

The proportion of import discount subsidy should be determined according to the type of imported goods, and the proportion of import discount is different for different goods, so it is recommended to consult the relevant departments directly. The amount of technology imports declared for import discount funds refers to the amount of technology fees paid for the introduction of technologies in the Catalogue from non-affiliated enterprises through transfer, licensing, entrusted development, cooperative development, technical consultation, etc.

The legal maximum proportion of liquidated damages for economic contracts.

The statutory maximum proportion of liquidated damages for economic contracts is 30% of the actual loss. The liquidated damages for economic contracts are generally calculated in accordance with the contract, which can be negotiated and agreed upon by both parties in the contract, and the actual losses can be judged according to the circumstances of the breach.

Do I need a quota for rapeseed oil imports.

No quotas are required for rapeseed oil imports. According to the relevant laws and regulations, the varieties of agricultural products subject to import tariff quota management are: wheat (including its flour and grains), corn (including its flour and grains), rice (including its flour and grains), sugar, cotton, wool and wool tops.

Does ilmenite require an import license.

An import license is required for ilmenite. Ilmenite import enterprises shall, in accordance with the relevant provisions of the state, be registered with the administrative department for industry and commerce, obtain import and export business qualifications or handle the filing and registration of foreign business operators, and have independent legal person qualifications; The product quality has reached the current national standards, and has obtained ISO quality certification.

Soybean imports are min, which does require a license.

A license is required for soybean imports. Soybean imports need to mention CIQ (entry-exit inspection and quarantine) certificates; Special documents required for customs declaration of soybean imports: automatic import license.

Soybean exports are now not subject to license management, nor are they subject to export taxes, but they are only legal products.

docetaxel: is a phase m-cycle-specific drug that promotes the polymerization of tubules into stable microtubules and inhibits their polymerization, thereby significantly reducing the number of tubules and destroying the micronetwork-like structure. In vitro experiments have shown that it has cytotoxic effects on a variety of mouse and human tumor cell lines, and the anti-tumor reputation spectrum is wider than that of PTX.

It has a good effect on advanced breast cancer, ovarian cancer and non-small cell lung cancer. It also has a certain effect on head and neck cancer, pancreatic cancer, small cell lung cancer, gastric cancer, melanoma, and soft tissue sarcoma.

Docetaxel can only be used for intravenous drips. All patients must take an oral corticosteroid, such as dexamethasone, 16 mg daily for at least 3 days before the docetaxel instillation for at least 3 days before receiving docetaxel** to prevent allergic reactions and fluid retention.

English name] docetaxel

Other Names] Tasodi, docetaxel, docetaxel, taxy, taxotere, txt

Product name] Tessodi, Aisu, Dopafi.

Generic name] docetaxel injection.

Indications] mainly advanced breast cancer, ovarian cancer, non-small cell lung cancer, head and neck cancer, small cell lung cancer; It is also effective for stomach cancer, pancreatic cancer, melanoma, etc.

Usage and dosage] intravenous infusion administration, the single dose is 75 100mg m2, 75mg m2 for domestic use, 60 75mg m2 for combination use, intravenous infusion for 1 hour, repeated every 3 weeks. In recent years, many scholars at home and abroad have adopted the use of weekly **, the general single dose is 35 40mg m2, once a week, for 6 weeks, and stop for 2 weeks. It is recommended to start oral dexamethasone 8 mg every day every 12 hours for 3 days before taking doceze, Zhengpei, and paclitaxel.

This product should be dissolved in the solvent provided, and then diluted with sodium chloride injection or 5% glucose to a final concentration.

Preparation and specifications] docetaxel for injection: 20 mg; ②80mg。

Drug classification] antineoplastic drugs - cytotoxic drugs - drugs acting on tubulin.

Dosing instructions] 1When instilling docetaxel, the instillation rate should be within 20 drops per minute for 10 minutes.

2.During the infusion of docetaxel, vital signs should be closely monitored within 10 minutes, blood pressure should be measured 4 times, and allergic reactions should also be noted thereafter.

3.In principle, this product should not be used when bilirubin exceeds the upper limit of normal value and ALT and AST exceed the upper limit of normal value, and the AKP exceeds 6 times the upper limit of normal value.

Storage] 2 8, airtight, shading preservation.

Packing] vials. 20mg bottles, 80mg bottles.

Validity] Tentatively set at 12 months.

The difference between the two is mainly in terms of specifications (including the effective content of each stick) and manufacturer.

Because the production process of different manufacturers is different, the purity of the extracted drugs is also different, and the final efficacy and quality are also very different. Generally speaking, the effect of joint ventures, import companies, and relatively large domestic brand enterprises producing prescription injections is relatively better, and the results are relatively smaller.

In addition, the factors that affect the drug are also related to various factors such as its guide price and sales intermediary.

The main ingredient of this product is docetaxel, and its chemical name is 2AR-(2A,4,4A,6,9,(R, S),11,12,12A,12B)-1,1-Dimethylethoxycarbonylamino-carbonylpropionic acid12B-acetoxy-12-benzoyloxy-2A,3,4,4A,5,6,9,10, 11,12,12A,12b-dodecahydro-4,6,11-trihydroxy-4A,8,13,13-tetramethyl-5-oxo-7, 11-Methylene-1H-cyclodecaeno3,4benzo1,2-bxabutane-9-yl ester.