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Most secondary kidney diseases are caused by the primary disease, and kidney disease progresses as the disease progresses. When secondary kidney disease occurs, it is more serious and needs to be controlled for a long time, otherwise it will cause systemic pathologies and serious kidney damage.
Which secondary kidney diseases are common?
1. Henoch-Schonlein purpura nephritis.
Henoch-Schonlein purpura nephritis is mainly caused by the primary disease of Henoch-Schonlein purpura, which is also a relatively common blood disease, often occurring in adolescents, and ** purpura will appear in the early stage, which will cause symptoms such as joint pain and abdominal pain in patients.
During the attack of Henoch-Schonlein purpura, it will affect blood circulation and coagulation function, bleeding symptoms are more common, so it will affect kidney function, easy to cause hematuria and urine protein, and in severe cases, it will directly damage the kidneys and cause nephritis.
2. Systemic lupus erythematosus nephritis.
Lupus nephritis is a relatively common secondary nephritis, mainly caused by systemic lupus erythematosus, the early symptoms of lupus erythematosus are obvious, as the disease progresses, the patient's urinary function and urine will be abnormal, which means that lupus erythematosus affects kidney function. Once lupus nephritis occurs, it will cause damage to the body system and need to be controlled as soon as possible to avoid affecting the patient's life.
3. Diabetic nephropathy.
Diabetic nephropathy is also the most common kidney disease in the elderly and the most typical secondary kidney disease. Long-term diabetes will affect blood circulation, and high blood sugar in diabetic patients will also cause various complications in the body, and kidney lesions are also the most common condition.
Diabetic nephropathy is difficult to control, and diabetes needs to be controlled for a long time, and if it fluctuates greatly, it will affect kidney function, and when kidney function is problematic, it will increase the difficulty of blood sugar control, which is easy to form a vicious circle.
4. Myelomatous nephropathy.
Middle-aged and elderly people are more likely to develop myelomatous nephropathy, mainly due to kidney lesions caused by myeloma, most of which are features of multiple myeloma. In the early stage, patients may develop glomerular damage, which means that chronic nephritis has developed, and if it continues to develop, in addition to nephrotic syndrome, it may also cause kidney failure, uremia, etc. This is also a relatively serious secondary kidney disease, the primary disease is difficult to control, and the kidney problem will gradually worsen, which will also affect the whole body.
Tips: Secondary kidney disease may be more harmful to the body than primary kidney disease, according to the cause of kidney disease to judge, when the disease causes kidney problems, you need to actively control the primary disease, otherwise it will accelerate the aging of kidney function.
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First, congenital factors, some patients after birth, the body is extremely lacking in nutrients, resulting in malnutrition, so that in the long run, it is likely to lead to abnormalities in the body's functions, and at the same time, the kidneys will also be implicated, resulting in the onset of nephritis. 2. Unreasonable diet, picky eater, overeating. If the daily nutrition is insufficient, it will lead to the body's normal metabolism **, and in the long run, it will lead to weakness.
3. Infection, whether it is a respiratory tract infection or a gastrointestinal infection, will bring different degrees of damage to the body, increase the burden on the kidneys, and cause the onset of nephritis.
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There are four possibilities to cause nephritis, the first is uremia, the second is cast-type urine, the third is proteinuria, and the fourth is anemia, all of which can induce nephritis.
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Nephritis may cause Henoch-Schonlein purpura nephritis, diabetic nephropathy, lupus nephritis is a relatively common secondary nephritis, mainly caused by systemic lupus erythematosus, and the early lupus erythematosus symptoms are obvious
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What causes nephritis.
1. Glomerulonephritis caused by bacterial infection is mainly related to hemolytic streptococcal infections such as upper respiratory tract infection, ** infection, scarlet fever, etc., and other bacterial infections such as staphylococcus, pneumococcus, typhoid bacillus, diphtheria bacilli and other causes can also cause nephritis glomerulonephritis caused by viral infection, such as influenza virus, mumps virus, hepatitis virus, measles virus, chickenpox virus, etc.
What causes nephritis.
2. The virus can directly invade the kidney tissue, or it can use the virus as the antigen to cause immune complex nephritis. It can be seen that the prevention of infectious diseases is of great significance for the prevention and treatment of glomerulonephritis.
What causes nephritis.
3. Different types of glomerulonephritis can also be caused by parasitic infections (such as schistosomiasis), protozoan infections (such as malaria parasites), biotoxins invading the body (such as pollen, bee venom), drugs (such as penicillamine), heavy metals (such as gold, mercury, bismuth), endogenous antigens, malignant tumors, benign tumors, etc.
The above are the main causes of nephritis. No matter what causes nephritis, it must be detected early.
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Nephritis can be caused by a variety of causes, such as common infections, exertion, and autoimmune diseases such as lupus, Sjogren's syndrome, and more. In addition, hypertension, diabetes, hyperuricemia, multiple myeloma, viral hepatitis B and Henoch-Schonlein purpura, as well as hereditary diseases are also common causes of nephritis. In addition, the formation of related immune complexes caused by antineutrophil cytoplasmic antibodies and antiglomerular basement membrane antibodies is also a common cause of nephritis.
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There are many reasons for nephritis, including the following: 1. Pathogens, common bacteria, viruses, parasites, protozoa, etc., can cause acute infection of the kidney, and inflammation occurs, so that the kidney function declines sharply and manifests as nephritis; 2. Patients take some drugs orally, heavy metals, etc., which will reduce kidney function and cause damage to the kidneys, which is drug-induced damage; 3. Some tumors, common benign and malignant tumors can cause kidney involvement and nephritis; 4. Caused by other diseases, such as allergenic purpura, hepatitis, diabetes, systemic lupus erythematosus, etc.; 5. The patient's own immune dysfunction; 6. Genetic factors.
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Whether nephritis is inherited or not depends on what kind of nephritis is inherited. Some nephritis is hereditary, especially hereditary nephritis, which can be passed from parents to children, and is an autosomal dominant disorder that can be passed on to offspring. The cause of this hereditary nephritis is not well known to the medical community, but it is thought that it may be caused by a genetic defect in the synthesis of the glomerular basement membrane.
One of the characteristics of this disease is that there is a clear family history, often in several generations of a family member, multiple people have hematuria, hematuria is the most common manifestation of hereditary nephritis, especially in young men. Hereditary nephritis is a disease that usually begins with subtle symptoms and is often mild proteinuria and hematuria on urine tests only, often worsening after strenuous exercise or upper respiratory tract infection. Proteinuria generally worsens with age, and in some cases, proteinuria may be severe.
Elevated blood pressure rarely occurs, and it is often not mildly elevated until late in the process. The disease often continues to progress slowly, and the disease is more severe in men, often dying of chronic kidney failure in the prime of life, and women have milder disease and can have a normal life expectancy.
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Nephritis is divided into two types, one is pathological factors, which are related to the pathological changes of the excess kidney itself; The second is caused by the interference of external factors, which induces kidney tissue lesions.
Nephritis**1: Destruction of immune complexes.
Immune complex formation, i.e., the combination of antibodies and insoluble glomerular antigens inherent in the glomeruli or non-glomerular antigens implanted in the glomeruli to form immune complexes in situ. Due to the different nature of the antigen and the antibody response it causes, immune complexes can form at different sites of the glomeruli. The deposition of immune complexes in the glomeruli does not in itself directly cause glomerular damage.
Immune complexes are formed in situ or deposited in the glomeruli through the blood circulation and can activate various inflammatory mediator systems, causing glomerular injury. The major mediator systems include the complement system, inflammatory cells such as individual leukocytes and monocytes, and the coagulation system.
Glomerular progressive sclerosis is caused by changes in intraglomerular hemodynamics, including high intraglomerular perfusion, high basal membrane pressure, and high filtration pressure. Factors that cause hemodynamic changes in the glomerulus include the compensatory process of the preserved nephrons, some endocannabinoids that affect the expansion of the incoming and outgoing arterioles, and the excessive amount of protein, phosphorus, and fat in the diet.
Nephritis**2: External factors.
Bacterial infections, mainly streptococcus, but also staphylococcus, pneumococcus, typhoid bacillus, diphtheria bacillus, leprosy bacilli, Treponema pallidum and infections from rickettsia; Viral infections, including measles, chickenpox, hepatitis B virus, K-B virus, mumps, zoster, and certain neoplastic viruses; Infections of parasites, such as Plasmodium, Schistosoma montonia, Loa loa, Trypanosome, etc.; Mold infections, such as Candida albicans, etc.; Biotoxins invade the body, such as pollen, bee venom, snake venom, etc.; drugs, such as penicillamine; Heavy metals such as gold, mercury, lead, etc.
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Nephritis is an immune disease. Infection is often triggered.
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It is mostly caused by colds, fevers, tonsil inflammation, drug damage, allergies, etc., resulting in a decrease in the secretion of hormones in the patient's body, and the abnormal immune response of the kidneys cannot be inhibited.
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There are many kinds of diseases that lead to kidney disease, such as insufficient congenital hormone secretion, wind, cold, summer, dampness, dryness, fire, external organs, diet, work and rest, accidental injuries and other internal and external factors can cause disease. And in the process of the occurrence and evolution of the disease, ** and its pathological products often interact with each other, causing each other to cause and effect, resulting in aggravation of the disease.
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Immune disorders, usually associated with streptococcal infections.
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1. Some patients are extremely deficient in nutrients in the body after birth, resulting in malnutrition, which is likely to lead to abnormal functions of the body in the long run, and at the same time, the kidneys will also be implicated, resulting in the onset of nephritis. For such people, we must pay attention to the daily nutrition supplement and carry out effective ** in a timely manner.
2. Another reason for the onset of nephritis is unreasonable diet, including picky eating, overeating, etc. If the daily nutrition is insufficient, it will lead to the body's normal metabolism not being high, and in the long run, the body will be in a state of weakness and fatigue, and eventually cause nephritis.
3. If the patient has a variety of infections, it will also induce nephritis. Whether it is a respiratory tract infection or a gastrointestinal infection, it will bring different degrees of damage to the body, and eventually aggravate the negative osmosis of the kidneys, and Cong Songchun will cause the onset of nephritis.
4. Changes in the patient's genes (mainly referring to gene mutations here) may also cause the onset of nephritis. In general, gene mutations occur in the embryonic stage, because they are affected by various factors, which will cause changes in the patient's genes, which will lead to kidney lesions and nephritis.
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1. Urinary tract infection, the main one of pyelonephritis in urinary tract infection**2, blood infection. When bacteria circulate through the kidneys, cysts form in the renal cortex, which can spread to the renal pelvis, causing pyelonephritis. 3. Diabetes.
Patients with a history of diabetes for up to 10 years have a higher chance of contracting upper pyelonephritis3, high blood pressure, and long-term hypokalemia.
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