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Stem cells are early, undifferentiated cells that have the ability to replicate and can differentiate into various tissues. Although the research of hematopoietic stem cells has a history of decades, the extensive and in-depth study of the biological characteristics and differentiation mechanisms of various stem cells, as well as the modification and modification of stem cells in vitro to use them for the most advanced diseases, "stem cell bioengineering" has only flourished in the last three years.
Hematopoietic stem cells are like human hematopoietic organs"Seeds"Our blood cells (red blood cells, white blood cells, platelets) are all differentiated and matured from it. Hematopoietic stem cell transplantation is currently the most effective method for leukemia, and many malignancies and genetic diseases, as well as aplastic anemia, can also be obtained through this method.
Hematopoietic stem cell transplantation works exactly the same as bone marrow transplantation, except that hematopoietic cells are collected differently. Most of the hematopoietic stem cells exist in the bone marrow, and bone marrow transplantation requires bone marrow to be extracted from the bone marrow cavity through bone marrow puncture, and then hematopoietic stem cells are collected and transfused into the patient's body. Stem cell transplantation involves the release of hematopoietic stem cells from the bone marrow into the bloodstream, and the collection of hematopoietic cells from the peripheral blood through a blood cell separator.
For bone marrow transplantation, the volunteer donor is given a local anesthetic and several holes in the ilium to extract hundreds of milliliters of bone marrow mixture. Stem cell transplantation only needs to collect blood from the volunteer's vein, and enrich it by a machine to infuse the blood back into the human body, only 50 ml of stem cells are needed, and due to the balance of the total amount of inflow and out, the donor will not produce circulatory disorders after collection, which is very safe for the human body.
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First of all, although leukemia is a refractory disease, with the current level of medical care, leukemia is no longer an incurable disease. Secondly, there are many types of leukemia, and bone marrow transplantation is now not the first choice at home and abroad. And many types of leukemia can be done without a transplant.
If accompanied by t(15; 17)(q22;Q12) or PML RAR-positive acute myeloid leukemia, childhood B-cell acute lymphoblastic leukemia (without BCR ABL, MALL genes), with T (8; 21) or AML1 ETO-positive acute myeloid leukemia with myelodyseosinophils and INV(16)(P13Q22) or T(16; 16)(p13;Q22), (CBF Myhii) and other types of leukemia, the first choice is no longer bone marrow transplantation, and the preferred method is conservative, including chemistry, traditional Chinese medicine, and cellular immunity, and its rate has far exceeded that of bone marrow transplantation.
It is best to stratify the syndrome according to the severity of the patient's condition**. You can refer to the episode of "Blood Cancer Life and Death" reported by CCTV, which is the first case of 2 leukemias, which can be referenced.
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Hello, bone marrow transplantation is only one of the methods of leukemia, not the only one, not all leukemia patients have to do bone marrow transplantation, the main types of leukemia programs: chemistry, radiation, traditional Chinese medicine, only some high-risk patients, bone marrow transplantation is required, and at the same time, most leukemia patients can survive without disease for a long time, or even be cured.
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omg。Total body exchange transfusion? Did you get it? The reason for the replacement of bone marrow is because the bone marrow is a hematopoietic organ, which can produce new and healthy blood, which is fundamentally cured, and the so-called exchange of blood is technically unrealistic, and if rejection occurs, people will definitely die.
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If leukemia patients have bone marrow transplantation, it is best to carry out holophase and bone marrow matching to improve the rate, but if there is no suitable bone marrow, the combination of Western medicine can be applied.
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If the hematopoietic stem cells are broken, even the whole body exchange blood will not work.
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Because bone marrow is responsible for making the body's blood cells!
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What do leukemia patients need to pay attention to after a bone marrow transplant? For people with certain types of leukemia, a bone marrow transplant may be used. However, after a bone marrow transplant, there are certain aspects that patients should pay special attention to.
Otherwise, it may affect the healing effect of the bone marrow transplant and lead to leukemia**, which is not conducive to the recovery of the body. Some people with leukemia opt for a bone marrow transplant**Leukemia, but after a bone marrow transplant, the patient's function and the body's own immune system are still weak.
<> if we don't do a good job of breastfeeding and ** work, leukemia may go down. When breastfeeding a leukemia patient after a bone marrow transplant, dietary regulation is very important. Patients with leukemia should pay attention to the following aspects after transplantation:
Yes, the bone marrow is suppressed for a period of time after a leukemia transplant. During myelosuppression, it is necessary to do a good job of the patient's **, requiring the patient to eat a clean diet and avoid eating in crowded places to avoid infection.
There are several problems after bone marrow transplantation because bone marrow transplantation, i.e., after stem cell transplantation, donor cells colonize, differentiate, and mature in the patient's body, so there are different aspects involved; We should focus on whether bone marrow and donor stem cells can**. Then we should regularly check his blood components, bone marrow, and some of his systemic indicators. The patient touches the doorknob and then touches the mouth, nose, or eyes, which is a big concern.
Post-transplant patients usually wash their hands every day, most commonly infections caused by hand contact. Many viruses and bacteria are transmitted from one person to another through many everyday contacts, such as doorknobs. If the patient touches the doorknob and then touches the mouth, nose, or eyes, this is a big concern.
Personal hygiene. Personal hygiene is very important after the transplant. You should bathe frequently with soap and shampoo.
Severe patients also experience gastrointestinal bleeding, including intracerebral hemorrhage, which can be life-threatening. Therefore, leukemia patients should take care to prevent infection and bleeding after transplantation.
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It's just a matter of whether you can be sick.
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