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This is not an infectious disease, it is a type of blood disease, myelofibrosis is divided into primary and secondary, primary myelofibrosis, also known as idiopathic myelofibrosis. **Unspecified. Animal experiments have found that certain chemicals, drugs and viruses can induce the disease, and people who are exposed to toluene, benzene, and ionizing radiation environmental pollution are prone to disease.
Secondary cases may be seen in chronic myeloid leukemia, polycythemia vera, essential thrombocythemia, myelodysplastic syndromes, and multiple myeloma. In general, secondary cases are caused by a definite disease. What we usually call myelofibrosis is primary myelofibrosis.
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Myelofibrosis, referred to as bone fiber, is a fibroproliferative disease caused by collagen hyperplasia in the hematopoietic tissue of the bone marrow, which seriously affects the hematopoietic function.
After the disease, patients will have left upper quadrant pain and upper abdominal distension, myelofibrosis will also appear tachycardia and low-grade fever sweating due to increased metabolism, in the first myelofibrosis is mainly to improve the hematopoietic function of the bone marrow, patients with severe anemia can be transfused**, conditional patients can also undergo bone marrow transplantation, but bone marrow transplantation has certain adverse reactions, so patients should also choose carefully.
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Myelofibrosis refers to the replacement of bone marrow hematopoietic tissue with fibrous tissue, which affects hematopoietic function, accompanied by extramedullary hematopoiesis of spleen, liver and other organs. The pathogenesis of the disease has not been elucidated, and fibroblast proliferation is presumed to be reactive and secondary lesions with increased cytokine sensitivity, while hematopoietic cells develop clonal or neoplastic proliferation.
Guidance: Myelofibrosis has a certain relationship with genetic production, but it can only be said that there is a certain genetic probability. Hope it helps.
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Hello, according to what you said, myelofibrosis is first divided into primary myelofibrosis and secondary myelofibrosis, primary myelofibrosis generally has a median survival of about 15 years in the low-risk group, and about 3 years in the high-risk group.
Generally aggressive integrative medicine** can prolong survival. The specific survival time of secondary myelofibrosis depends on the detailed primary disease.
However, the specific situation depends on the patient's individual constitution and the best effect.
I wish the patient a speedy **!
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Primary myelofibrosis is a chronic blood disease, and it is often difficult for patients to use Western medicine, and the disease can only be controlled for a short time.
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Myelofibrosis, referred to as "bone fiber" or "myeloid fiber", is a myeloproliferative disease caused by the proliferation of collagen fibers in the hematopoietic tissue of the bone marrow, and its fibrous tissue seriously affects the hematopoietic function. Bone fiber often has a slow onset, and there may be no symptoms in the early stage, and then gradually appear weakness symptoms such as fatigue, night sweats, palpitation, paleness, shortness of breath, abdominal pain, abdominal mass (splenomegaly), bone pain, etc.; Laboratory tests showed that most patients showed mild to moderate anemia, and advanced anemia could be severe, and teardrop-like red blood cells, young granules, and erythrocytes could be seen in peripheral blood; Bone marrow aspiration, because the bone is hard, often unable to extract bone marrow fluid, is called "dry pumping".
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Fibrosis is a myeloproliferative disease of the blood system, mainly originating from hematopoietic stem cells, which can lead to diffuse fibrous tissue proliferation in the bone marrow. And it can appear extramedullary hematopoiesis in the spleen, liver, and lymph nodes, causing anemia, enlargement of the spleen, and sclerosis of bones. There is no specific approach, and most patients are given symptomatic support.
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Myelofibrosis (MF) is abbreviated as myeloid fiber. It is a myeloproliferative disease caused by collagen hyperplasia in bone marrow hematopoietic tissue, and its fibrous tissue seriously affects hematopoietic function. The disease has different degrees of bone marrow fibrous tissue hyperplasia, as well as extramedullary hematopoiesis that mainly occurs in the spleen, followed by the liver and lymph nodes, the typical clinical manifestations are erythrocyte and myelocytic anemia, and there are more teardrop-shaped red blood cells, bone marrow aspiration often appears dry pumping, the spleen is often obviously enlarged, and has different degrees of bone sclerosis.
This disease is a rare disease with an incidence. The age of onset is usually between 50 and 70 years, but it can also occur in infants and young children, and is slightly higher in males than in females.
There is a genetic predisposition to any disease, but the chance of being actually inherited is very small, so it is better to worry less. Less anxiety and a happy mindset are the magic weapons to prevent cancer!