Please help analyze the immunohistochemistry results of breast cancer, thank you!

Immunohistochemistry is just a way to help determine what to follow. First of all, it is best to be surgically resected, if it cannot be cut, neoadjuvant chemotherapy should be done first, and then surgery, so that there is a chance**. This is followed by regular postoperative chemotherapy.

Endocrine** can be used for several years after chemotherapy (this is based on immunohistochemistry results). If economic conditions are good, targeted** can be added to postoperative chemotherapy (also based on immunohistochemistry results). There are many chemotherapy regimens for breast cancer, so let the oncologist determine the situation according to the situation, and the liver cyst has no effect.

Progress** is not based on your immunohistochemistry, but on the clinical stage after your surgery.

There are no specific sentinel lymph nodes, the situation you mentioned is indeed a common clinical problem, the lymph nodes taken are not enough, and the others that are not taken may be metastasized.

I basically agree with the opinion of the person upstairs "The current stage is pt1n0m0, the ia stage, which belongs to the early stage, but the degree of differentiation is poor, and the probability is relatively high. If the patient can be persuaded to do postoperative adjuvant chemotherapy, and then endocrine **, whether it is "tamoxifen" or "aromatase inhibitor" should be determined by the doctor according to the patient's condition. ”

Supplement: Patients who are 60 years old and are postmenopausal women should benefit more from aromatase inhibitors**. In addition, don't believe in any immunity**, biology**, there is no definite effect.

Low to moderately severe, sensitive to hormones, **low probability. Just use the usual chemotherapy regimen.

I wrote a sentence on the puncture pathology report about the right armpit slag This slag, it must be a mistake, take a good look and write it again.

My mom's FISH results are out, and HER2 is negative, which is a good sign, which means that you don't need to use the very expensive chemotherapy drug Herceptin. Only general chemotherapy is required.

The results of immunohistochemistry are relatively optimistic, estrogen and progesterone receptors are positive, oncogene receptors are also positive, chemotherapy can be used after surgery, or combined with endocrine**, and further FISH can be done to see if it is combined with Herceptin chemotherapy.

Bai Yongli Cancer Mo Zhizhu is full of confidence, and the immune tissue is a report on the diagnosis of breast cancer, and the blood picture and liver function are checked regularly. Because radiotherapy and chemotherapy have greater cytotoxicity, not only to tumor cells, but also to normal cells, which may cause bone marrow suppression and serious decline in white blood cells, and may also cause damage to liver cells. If there is a severe decrease in white blood cells and significant impairment of liver function, a change in protocol should be considered.

The decoction of traditional Chinese medicine is taken internally and externally, and the effect is very good.

1. First of all, it is necessary to clearly understand that chemotherapy is not the best way to cancer, and chemotherapy cannot guarantee that it will be effective for any cancer. Chemotherapy is only a way that can be considered to alleviate the damage of cancer disease to a certain extent when human beings seriously threaten the lives of patients with cancer, and chemotherapy may cause some harm to patients and even lead to new cancer diseases while effectively alleviating the disease.

So chemotherapy can be said to be a "last resort" option.

2. Secondly, the data (figures) of any single examination cannot be used as a basis for directly judging whether chemotherapy is necessary. Whether chemotherapy is needed or not must first consider whether the patient can afford the possible harm caused by the corresponding chemotherapy; Secondly, the necessity of chemotherapy (efficacy, efficacy, ......) should be consideredA single test can only be the "tip of the iceberg" of many bases for determining the need for chemotherapy.

The immunohistochemistry results of breast cancer are still relatively reliable, so what is the analysis of the immunohistochemistry results of breast cancer and the first time?

Immunohistochemistry of breast cancer is of great significance for the staging and prognosis of breast cancer. The analysis of the results of immunohistochemistry of breast cancer is mainly carried out from the following aspects, one is hormone receptors, including estrogen receptor ER and progesterone receptor PR. Receptor expressing (+) requires endocrine **, such as tamoxifen, letrozole, alatrozole, etc.

There is also the human epidermal growth factor-2 receptor, which is positively expressed, has a relatively poor prognosis and requires the use of targeting**. and ki-67, with high expression of ki-67, implying a poor prognosis.

Among them, patients with basal cell breast cancer are all negative for ER, PR, and HER2, and 75% of patients will have TP53 mutations, as well as BRCAI (tumor suppressor gene) mutations, and Ki-67 is negative for acorn. This type of breast cancer is 85% triple-negative breast cancer and has a shorter survival period than other types.

T2N0M0 stage IIA stage.

The first chemotherapy had white blood cells that were so low. Or a change of option should be considered.

The others basically agree with the professional views of Qishi 1983.

There are a lot of chemoradiotherapy, and it is necessary to do further to prevent the occurrence of complications or sequelae After understanding the situation in detail, I will help you analyze the relevant Q chat.

Hello, considering the situation described above, it is recommended that patients use the latest tumor technology specific anti-tumor immunity, which is non-toxic, non-invasive, effectively improves the patient's immunity, and can also control the metastasis of the disease. Hope it helps.

Question: Can you tell if it is highly differentiated or underdifferentiated?

Solid adenocarcinoma is poorly differentiated.

Acinar and adherent are highly differentiated.

Question: Is the problem of low differentiation more serious than the problem of high differentiation?

Spread faster, huh?

Question: In a case like the one I posted, I have undergone surgery, chemotherapy and radiotherapy, is it possible to follow up**?

Two metastases have been seen in 11 groups of lymph nodes.

Question: Is this early, middle, or late?

Wait a minute, I'll take a look.

According to the information you have given so far, the only regrettable thing is that the lump is larger, and the immunohistochemistry is quite ideal.

Immunohistochemistry of breast cancer mainly depends on the expression results of ER, PR, CEB-2 and KI67.

ER and PR are hormone receptor manifestations, with a high positive rate, good, with medicine to eat, sensitive to endocrine **.

CEB-2 anti-cancer gene test, negative. Good, low rate of transfers.

P53 negative, good, low metastasis** rate.

ki67, cancer cell proliferation effect detection, 15% is not bad.

Immunohistochemistry root lymph nodes have little to do with it.

ER and PR are estrogen and progesterone receptors, and positive results indicate that the tumor is hormone-dependent and sensitive to endocrine, that is, oral tamoxifen, anastrozole, letrozole, toremifene and so on.

CERBB-2, which is a genetic level test, is sensitive to biological ** when it is strong positive, and represents the drug, Herceptin, which is expensive and cannot be borne by ordinary families.

If there is nothing special in the patient's condition, it is recommended to insist on taking tamoxifen for 5 years, 10mg, 2 times a day; Endometrial ultrasound should be repeated every six months.

The condition of lymph nodes is in the macropathology, not in immunohistochemistry. So wonder no more!

It can be combined with traditional Chinese medicine**, on the one hand, conditioning, on the other hand**.

Immunohistochemistry is only an indicator of antigen and antibody response, did the patient do pathological examination after surgery? Add q to help you analyze the relevant inspection report in detail.