What are the main causes of vitiligo?

The condition of vitiligo is now unclear and may be related to immune dysfunction in the body. Therefore, it is necessary to pay attention to adhere to the local ** cleansing, and together with a clear diagnosis, ultraviolet light therapy can be actively used in the future, which is the best treatment.

The main causes of vitiligo are generally related to immunity, malnutrition, trauma, living environment, etc.

Vitiligo is depigmented plaques caused by the absence or reduction of melanocytes. At present, the cause of the disease is not clear, and clinical studies have shown that it is often related to the following factors: genetic factors, psychiatric and neurological factors, autoimmune factors, melanocyte self-destruction, endocrine factors, poor utilization of trace elements, exposure to chemicals and infections.

**Don't be blind**, find out where the root cause is**. It is recommended not to use drugs blindly, **There are many drugs for vitiligo, but they all have certain indications, not necessarily suitable for every patient, if the medication is not right, it will lead to the aggravation of vitiligo, if it is used for a long time, it may cause some damage to liver and kidney function, and it will aggravate the condition.

The condition of vitiligo is unclear and may be related to genetics, autoimmune disorders, environmental and disease factors. The basic change is the loss of melanin in the epidermis leading to vitiligo, so any cause of the decrease in melanin can be considered directly related to melanin.

Direct cause. Decreased melanin production.

Autoimmune disorders cause immune cells to attack their own melanocytes, resulting in a decrease in melanin production, so vitiligo can coexist with a variety of autoimmune diseases such as hyperthyroidism. In addition, certain neurological diseases, such as viral encephalitis and multiple sclerosis with Horner syndrome, lead to an increase in the release of biochemicals from nerve endings, which have a destructive effect on melanocytes, resulting in a decrease in melanin production and vitiligo.

Increased melanin destruction.

In the process of melanin synthesis, if toxic phenolic compounds are formed, it can cause increased destruction of melanin, resulting in vitiligo. Long-term use of chemical products such as hair dyes, detergents, etc., may induce vitiligo.

Other factors. **Injury: Severe sunburn or trauma directly leads to **injury, or contact with certain chemicals in life, resulting in **barrier destruction, promoting the body's oxidation should be stimulated, and inducing the occurrence of vitiligo.

Psychiatric factors: Overwork, anxiety or stress may induce immune system disorders, leading to autoimmune dysfunction and inducing vitiligo.

Family history: Studies have shown that vitiligo has a familial predisposition, so having a vitiligo presence in a Grade 1 relative (parents, siblings, children, etc.) is also a risk factor.

Trauma: Trauma can induce immune dysfunction and is one of the risk factors for vitiligo.

The specific ** of vitiligo is unknown, and it may be related to the following factors: 1. Genetic theory, about 25%-30% of patients have familial, and studies have shown that vitiligo is a polygenic genetic disease. Second, the theory of melanocyte self-destruction, when melanocytes are hyperfunctional, the intermediate products of melanocyte synthesis accumulate excessively, destroying the synthesis of melanocytes, and other external substances such as phenols, catecholamine compounds, etc. can also destroy melanocytes, and people who are exposed to such substances may also develop diseases.

3. Neurochemical factors, skin lesions occur and expand during stress, and vitiligo can be neurosegmental, which indicates that the onset of vitiligo is related to mental factors. Fourth, the theory of autoimmunity, vitiligo may be complicated by many autoimmune diseases, such as thyroid disease, pernicious anemia, ulcerative colitis, etc. 5. The relative deficiency of trace elements such as tyrosine and copper ions is also one of the causes of vitiligo.

The rate of vitiligo cannot reach 100%, but with the gradual increase of the current means, the rate is gradually increasing. At present, various methods such as oral and topical drugs, phototherapy, depigmentation**, masking**, vitiligo epidermal transplantation, melanocyte transplantation, etc.

1 All causes of vitiligo may be due to these factors:

1. Suffered mental trauma before illness, or severe psychological pressure.

2. Traumatic infection, chilblains, scalds, etc. before illness.

3. The climate of the place of residence is humid.

4. Excessive fatigue and serious lack of sleep.

5. Have had other ** diseases before the onset of the disease.

6. Immediate family members have this disease.

7. Onset in spring and summer and aggravation in this season.

8. Have other immune diseases, endocrine diseases (such as: hyperthyroidism, diabetes, etc.) 9. Serious pollution in the city or pesticide pollution in the countryside.

10. Partial eating.

11. Hair dyeing.

12.Just renovated the house and lived in.

13.Low immunity and frequent colds.

14. Military training, exposure to the sun.

There are many factors that cause vitiligo, and so far the following factors have been summarized:

1.genetic factors; Vitiligo has a certain genetic probability, and only a few cases of vitiligo are related to heredity, so the genetic probability of vitiligo patients is relatively small, and the genetic probability will generally be reduced later. Although it is genetic, it does not affect the ** of vitiligo.

From a genetic point of view, heredity is only one factor in the onset of vitiligo, and most patients with vitiligo are caused by acquired factors.

2.psychiatric neurological factors; With the increase of social pressure, although some people have a strong psychological tolerance, they will also fall into depression when they encounter a huge blow from emergencies and exceed the psychological tolerance limit. Long-term psychological stress and excessive mental stress can lead to endocrine disorders, immune dysfunction and induce vitiligo.

3.chemical factors; In recent years, it has been found that large amounts of fluorine refrigerants are emitted to damage the ozone layer in the atmosphere, causing excessive ultraviolet rays to reach the earth's surface, which can cause harm to the human body. Excessive use of chemicals in crops, such as pesticides, fungicides and ripening agents, and excessive feeding of carnivorous poultry to growth hormone residues after slaughter will cause adverse effects on human health.

4.Tyrosinase and copper ions are relatively deficient factors; Lack of tyrosine in the diet will also affect the synthesis of melanin, so vitiligo patients should eat more foods rich in tyrosine, zinc, iron and other substances, such as lean meat, eggs, various animal offal, milk, loofah, eggplant, carrots and other fresh vegetables and soy products.

The factors that cause vitiligo are related to many factors in our lives, as well as infectious factors; traumatic factors and so on. Due to the influence of bad environment, bad diet, and bad mood, our body's immunity decreases, viscera metabolic dysfunction, and many other factors.

Vitiligo is an acquired disease caused by depigmentation. It is mainly related to the following factors: genetic, chemical, traumatic, endocrine, autoimmune, neuropsychiatric, melanocyte self-destruction and other factors.

Heredity does not account for a very high proportion of the incidence of vitiligo, and heredity occurs under the influence of environmental factors. Endocrine disorders and immune imbalances will affect the production of melanin, which can easily induce vitiligo. When people are depressed, depressed and nervous, they are prone to damage melanocytes, inhibit the production of melanin, and cause vitiligo.

Melanocytes are highly susceptible to damage in the chemical or traumatic environment, affecting the production of melanin, which in turn leads to vitiligo. Only by going to a regular hospital to receive a professional examination can we identify the causative elements and carry out effective symptomatic treatment.

The cause of vitiligo is extremely complex, whether we want to prevent or want to prevent such a disease, of course, there are many difficulties, for patients with vitiligo disease, we must pay attention to early detection and early detection, so it is the key to the effectiveness of the disease, so it is necessary to pay attention to what is the cause of vitiligo disease?

What causes vitiligo.

1. Industrial pollution: The pollution caused by industrial sewage to the environment is one of the reasons for the increase in incidence in recent years. In recent years, it has been found that a large number of fluorine refrigerants emitted by large amounts of fluorine refrigerants have damaged the ozone layer in the atmosphere, resulting in excessive ultraviolet radiation to the surface, which will cause harm.

2. Neuropsychiatric factors: The pace of modern life makes some people psychologically overburdened, and they are anxious every time they encounter poor business. sometimes worry about losing your job; Government workers are overly concerned about interpersonal relationships and promotions.

Although some people are broad-minded and have a strong psychological tolerance, they will also fall into depression when they encounter a huge blow from an unexpected event, exceeding the limit of psychological tolerance. Long-term psychological stress and excessive mental stress can lead to endocrine disorders and immune dysfunction.

3. Traumatic infection: burns, scalds, and white spots form after infection. Trauma is the precipitating factor, and the disease occurs on the basis of disharmony between the body's qi and blood.

4. Agricultural pollution: excessive use of chemicals on crops, such as pesticides, fungicides and ripening agents, etc., and the residues in the body after overfeeding growth hormone slaughter of meat and poultry will have adverse effects on health.

5. Genetic factors: clinical observation, only a few cases are related to heredity, but do not affect the disease of the disease.

6. Deficiency of trace elements: trace elements are active substances involved in the intermediate links of body metabolism, such as copper, selenium, zinc, iodine, etc., which directly participate in the synthesis of melanocytes and protect melanocytes from heavy metal poison damage. Studies have shown that both trace element deficiencies and imbalances can lead to impaired melanocyte synthesis.

When suffering from the disease of vitiligo, we cannot blindly carry out the disease, we must take the best measures according to the symptoms of the disease, and only in this way can we effectively control the development of the disease and avoid causing too much harm to the patients with vitiligo.

Speaking of vitiligo, many people have heard of it, and the reason why everyone is so afraid of vitiligo is mainly because vitiligo is difficult, and it may also face diffusion, ** and other phenomena. There are many factors in life that can cause vitiligo. So let's briefly talk about what are the causes of vitiligo?

1. The lack of trace elements in the body, the lack of trace elements is often closely related to the daily diet, and the main factor leading to the deficiency of this element is partial eating. Partial eating is a big problem in people's diet, especially in children, and people's long-term partial eating will lead to malnutrition, resulting in a lack of trace elements in the body, resulting in a decrease or even disappearance of melanin, which leads to the onset of vitiligo, causing great physical and mental harm to patients.

2. The destruction of melanocytes themselves, vitiligo patients can produce antibodies and T lymphocytes, indicating that the immune response may lead to the destruction of melanocytes. The toxic melanin precursors synthesized by the cells themselves and some chemicals that cause ** decolorization may also have a selective destructive effect on melanocytes.

3. Industrial pollution in life, at present, industrial pollution is also one of the onset of vitiligo, and the exhaust gas, waste water and exhaust gas emitted by vehicles caused by industrial production have great harm to the human body. In recent years, excessive ultraviolet radiation has been applied to the earth's surface due to the destruction of the ozone layer in the atmosphere, and large amounts of ultraviolet radiation can cause damage to the human body, thus causing vitiligo. In recent years, there has been an increasing number of cases of vitiligo caused by environmental influences.

4. Genetic factors, vitiligo can appear in twins and families, indicating that heredity plays an important role in the pathogenesis of vitiligo. Vitiligo has been suggested to have incomplete penetrance and multiple pathogenic loci in the gene.

The above is a simple introduction, if you want to prevent vitiligo, you should pay more attention to the above reasons, avoid it, so as to stay away from vitiligo.

Genetic factors: Vitiligo is a multifactorial hereditary disease, although heredity is caused by a variety of factors, the probability of inheritance is relatively small, but it still has a certain chance of inheritance. If there is a history of vitiligo within three generations, it is likely that the patient's vitiligo is due to genetic factors.

Immune system factors: The immune system has a very important impact on the function of all parts of the body. If the body's immune system is weak, it will receive a lot of invasions that cause many diseases, which will hinder the delivery of nutrients needed by melanocytes, and then cause vitiligo disease.

Trauma: In fact, when the body is subjected to mechanical trauma, such as frostbite, burns, surgery, etc., such injuries can not only make the local ** white, but also may cause white spots far from the injured part. This is mainly due to damage to melanocytes, which induces immune dysfunction and causes vitiligo.

1.Genetics says that vitiligo runs in families. Some studies have suggested that vitiligo has incomplete penetrance and multiple pathogenic loci in the gene.

2.Autoimmune theory Vitiligo can be combined with autoimmune diseases, such as thyroid disease, pernicious anemia, etc. Specific antibodies to various organs, such as anti-thyroid antibodies and anti-adrenal antibodies, can also be detected in serum.

3.The theory of neurochemical factors may be related to neuropsychiatry, overwork, anxiety, etc.

4.Melanocyte self-destruction theoryThis theory believes that the early decline of epidermal melanocytes due to their hyperfunction leads to the occurrence of vitiligo.

The incidence in our country is: , young women are a vulnerable group.