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PrionsPrions are protein viruses, viruses that have only proteins and no nucleic acids. The 1997 Nobel Prize in Medicine or Physiology was awarded to the American biologist S. S. Prushiner b.
prusiner) was awarded for his outstanding contribution to the study of prions. Prions are not only closely related to human health and livestock rearing, but also provide important information for the study of other diseases related to dementia. As far as biological theory is concerned, the replication of prions is not based on nucleic acids, but on proteins, which will have a significant impact on the exploration of the origin of life and the nature of life phenomena.
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It is a protein virus.
There are no nucleic acids. It replicates with a protein as a template.
It seems that there is a disease related to cattle that is this virus.
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Prion is the meaning of protein, Ruan virus is a virus that only contains protein, and mad cow virus is a prion, which will synthesize messenger RNA with protein as a template in the organism, and then reverse transcribed into DNA embedded in the chromosomes of the organism, and replicate with the replication of biological cells, so as to reproduce.
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is a variant protein.
It's not a virus, mad cow disease is caused by it, 7 on biology books have.
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Prions, also known as protein infection factors. Prions are a class of small molecules, non-immunophobic hydrophobic proteins that infect animals and replicate within host cells.
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Nguyen virus is a type of virus that only has proteins and no RNA or DNA as genetic material.
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Prions, also known as protein infecting factors, virulences, or infectious proteins, are a class of small molecule non-immunophobic hydrophobic proteins that can infect animals and replicate in host cells.
Prion is the old name for protein, prion means protein virus, prion virus is not strictly speaking a virus, it is a class of self-replicating and infectious factors that do not contain nucleic acids but are composed of only proteins.
Prions are a class of infectious agents that can cause central nervous system pathologies in mammals and humans, and the American biologist Squelli Prusiner believes that they are protein-infecting particles.
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Strictly speaking, viruses are abiotic. They are cell-free and tiny, and their composition is peculiar, consisting only of nucleic acids and proteins. Nucleic acids (DNA or RNA) play an important role in the genetics of viruses, while protein coats only play a protective role against nucleic acids and are not heritable in themselves.
This is the basic understanding of the virus. However, with the in-depth study of some diseases, scientists have found that there is another class of substances that is different from ordinary viruses, it only has proteins and no nucleic acids, but it is both infectious and hereditary, and has abnormal characteristics that are different from all known traditional pathogens. It's a prion.
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Whether prions are biological or not, this is something that the scientific community has not yet decided, and even scientists cannot argue, there is no right answer at all. Here's just my opinion:
Prions are nucleic acid-free protein infectious agents that can cause mammalian central nervous system lesions. It is made up of a normal form of protein (PRPC) misfolded into a pathogenic protein (PRPSC). Two structural heterotypic proteins** in the same gene.
Proliferation of prions is achieved by the conformational transformation of PRPC into PRPSC.
1. The virus itself is synthesized under the control of the genes of the organism itself, and follows the central law of DNA and protein. Only some higher animals have this related gene, such as cattle, sheep, humans, etc. Animals that do not have this gene will never produce this protein, i.e., they will never develop the disease.
But have you ever heard of a creature that appears under the control of another creature?
For example, cats are genetically controlled to produce sparrows. Do you think it's weird?
2. Its proliferation depends on the presence of isomorphic proteins, which change the structure of isomorphic proteins.
This is very similar to the role of an enzyme, which catalyzes a change in the structure of another protein, but does not change itself. It's just that the substrate it catalyzes is more special.
If copying is a living thing, do you think a photocopier is a living thing? It can also be replicated.
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Yes, prions are protein viruses, viruses that only have proteins and no nucleic acids.
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As a prion is a molecular organism that contains only proteins and no nucleic acids and can only survive inside the parasitic host cell. Therefore, it is possible that the information required to synthesize prions is present in the host cell, and the role of prions is only to activate the genes encoded for prions in the host cell, so that the prions can replicate and reproduce.
Another theory is that prion proteins encode genetic information for themselves. This hypothesis is contrary to the "central law" of traditional molecular biology, because prions do not have nucleic acids. Therefore, it is hypothesized that the possible methods of prion replication are shown in the figure, and it is thought that the RNA or DNA encoded by the prion (in the latter case, reverse transcription) must be produced through the reverse translation process, and even reverse transcriptase must be present.
The second is protein-guided protein synthesis, that is, the protein itself can be used as genetic information.
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I took a look at the information.
It is said that there is a gene for the Nguyen virus in the human body.
But it is not pathogenic.
Presumably, this gene is not transcribed.
But when exposed to foreign protein viruses.
This gene is activated.
Start producing the virus yourself.
In this way, it is transmitted in the cells of the human body.
Somewhat similar to pneumococcus.
No cure... This is suicide ...
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Nguyen virus is, of course, a virus, and it is a special kind of virus because it is a virus that only has proteins and no nucleic acids. So its replication is replicated in proteins. Needless to say, the Nguyen virus is also a living thing.
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Yes, living objects are called living things.
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